Project name: 5xhf:A
Status: done
submitted: 2019-03-21 14:58:06, status changed: 2019-03-21 15:08:21
Settings
Chain sequence(s)
|
A: DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6832
-
Maximal score value
-
2.4985
-
Average score
-
-0.8621
-
Total score value
-
-182.7604
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
A |
-2.2650 |
|
2 |
I |
A |
0.0000 |
|
3 |
Q |
A |
-1.9951 |
|
4 |
M |
A |
0.0000 |
|
5 |
T |
A |
-1.1909 |
|
6 |
Q |
A |
0.0000 |
|
7 |
S |
A |
-0.8007 |
|
8 |
P |
A |
-0.6253 |
|
9 |
S |
A |
-0.8613 |
|
10 |
S |
A |
-0.6848 |
|
11 |
L |
A |
-0.5087 |
|
12 |
S |
A |
-0.7687 |
|
13 |
A |
A |
0.0000 |
|
14 |
S |
A |
-0.7760 |
|
15 |
V |
A |
0.2972 |
|
16 |
G |
A |
-0.5406 |
|
17 |
D |
A |
-1.7009 |
|
18 |
R |
A |
-2.2322 |
|
19 |
V |
A |
0.0000 |
|
20 |
T |
A |
-0.6492 |
|
21 |
I |
A |
0.0000 |
|
22 |
T |
A |
-0.6512 |
|
23 |
C |
A |
0.0000 |
|
24 |
R |
A |
-2.5703 |
|
25 |
A |
A |
-2.1450 |
|
26 |
S |
A |
-2.0305 |
|
27 |
Q |
A |
-2.6008 |
|
28 |
D |
A |
-2.4331 |
|
29 |
V |
A |
0.0000 |
|
30 |
N |
A |
-1.7487 |
|
31 |
T |
A |
-1.0030 |
|
32 |
A |
A |
-0.5251 |
|
33 |
V |
A |
0.0000 |
|
34 |
A |
A |
0.6728 |
|
35 |
W |
A |
0.0000 |
|
36 |
Y |
A |
-0.1308 |
|
37 |
Q |
A |
-0.9576 |
|
38 |
Q |
A |
-1.7081 |
|
39 |
K |
A |
-2.0854 |
|
40 |
P |
A |
-1.6692 |
|
41 |
G |
A |
-1.5742 |
|
42 |
K |
A |
-2.4586 |
|
43 |
A |
A |
-1.6237 |
|
44 |
P |
A |
-1.6305 |
|
45 |
K |
A |
-1.9815 |
|
46 |
L |
A |
-0.2188 |
|
47 |
L |
A |
0.0000 |
|
48 |
I |
A |
0.0000 |
|
49 |
Y |
A |
1.6648 |
|
50 |
S |
A |
0.5045 |
|
51 |
A |
A |
0.0000 |
|
52 |
S |
A |
0.7407 |
|
53 |
F |
A |
2.4985 |
|
54 |
L |
A |
1.9016 |
|
55 |
Y |
A |
1.4771 |
|
56 |
S |
A |
0.2930 |
|
57 |
G |
A |
-0.3087 |
|
58 |
V |
A |
0.0000 |
|
59 |
P |
A |
-0.2787 |
|
60 |
S |
A |
-0.3418 |
|
61 |
R |
A |
-0.7059 |
|
62 |
F |
A |
0.0000 |
|
63 |
S |
A |
0.2938 |
|
64 |
G |
A |
0.0239 |
|
65 |
S |
A |
-0.8464 |
|
66 |
R |
A |
-2.1900 |
|
67 |
S |
A |
-1.5640 |
|
68 |
G |
A |
-1.8606 |
|
69 |
T |
A |
-2.1087 |
|
70 |
D |
A |
-2.0258 |
|
71 |
F |
A |
0.0000 |
|
72 |
T |
A |
-0.8703 |
|
73 |
L |
A |
0.0000 |
|
74 |
T |
A |
-0.6058 |
|
75 |
I |
A |
0.0000 |
|
76 |
S |
A |
-1.2796 |
|
77 |
S |
A |
-0.9920 |
|
78 |
L |
A |
0.0000 |
|
79 |
Q |
A |
-0.8266 |
|
80 |
P |
A |
-1.3890 |
|
81 |
E |
A |
-1.9739 |
|
82 |
D |
A |
0.0000 |
|
83 |
F |
A |
-1.3868 |
|
84 |
A |
A |
0.0000 |
|
85 |
T |
A |
-0.9148 |
|
86 |
Y |
A |
0.0000 |
|
87 |
Y |
A |
-0.0276 |
|
88 |
C |
A |
0.0000 |
|
89 |
Q |
A |
0.2815 |
|
90 |
Q |
A |
0.0000 |
|
91 |
H |
A |
-0.4990 |
|
92 |
Y |
A |
0.1602 |
|
93 |
T |
A |
-0.3554 |
|
94 |
T |
A |
-0.4825 |
|
95 |
P |
A |
-0.4907 |
|
96 |
P |
A |
-0.4019 |
|
97 |
T |
A |
-0.1766 |
|
98 |
F |
A |
0.8500 |
|
99 |
G |
A |
-0.3727 |
|
100 |
Q |
A |
-1.1675 |
|
101 |
G |
A |
0.0000 |
|
102 |
T |
A |
0.0000 |
|
103 |
K |
A |
-1.3593 |
|
104 |
V |
A |
0.0000 |
|
105 |
E |
A |
-1.3994 |
|
106 |
I |
A |
0.0000 |
|
107 |
K |
A |
-1.7123 |
|
108 |
R |
A |
-0.9943 |
|
109 |
T |
A |
-0.2326 |
|
110 |
V |
A |
0.1083 |
|
111 |
A |
A |
-0.1190 |
|
112 |
A |
A |
-0.2905 |
|
113 |
P |
A |
0.0000 |
|
114 |
S |
A |
-0.1858 |
|
115 |
V |
A |
0.0000 |
|
116 |
F |
A |
1.2618 |
|
117 |
I |
A |
1.1387 |
|
118 |
F |
A |
1.2700 |
|
119 |
P |
A |
-0.1036 |
|
120 |
P |
A |
-0.9298 |
|
121 |
S |
A |
-2.0467 |
|
122 |
D |
A |
-3.4405 |
|
123 |
E |
A |
-3.6832 |
|
124 |
Q |
A |
-3.2085 |
|
125 |
L |
A |
-2.8572 |
|
126 |
K |
A |
-3.2325 |
|
127 |
S |
A |
-2.1173 |
|
128 |
G |
A |
-1.7179 |
|
129 |
T |
A |
-1.6765 |
|
130 |
A |
A |
0.0000 |
|
131 |
S |
A |
-0.1453 |
|
132 |
V |
A |
0.0000 |
|
133 |
V |
A |
0.5808 |
|
134 |
C |
A |
0.0000 |
|
135 |
L |
A |
0.6388 |
|
136 |
L |
A |
0.0000 |
|
137 |
N |
A |
-0.8268 |
|
138 |
N |
A |
-1.8485 |
|
139 |
F |
A |
0.0000 |
|
140 |
Y |
A |
0.0000 |
|
141 |
P |
A |
-1.9147 |
|
142 |
R |
A |
-3.2076 |
|
143 |
E |
A |
-3.2604 |
|
144 |
A |
A |
-2.3760 |
|
145 |
K |
A |
-2.3049 |
|
146 |
V |
A |
-1.2225 |
|
147 |
Q |
A |
-0.6052 |
|
148 |
W |
A |
0.0000 |
|
149 |
K |
A |
-0.3392 |
|
150 |
V |
A |
-0.6822 |
|
151 |
D |
A |
-1.5841 |
|
152 |
N |
A |
-1.4017 |
|
153 |
A |
A |
-0.0583 |
|
154 |
L |
A |
0.9314 |
|
156 |
S |
A |
-0.5980 |
|
157 |
G |
A |
-1.4484 |
|
158 |
N |
A |
-1.8279 |
|
159 |
S |
A |
-1.8356 |
|
160 |
Q |
A |
-2.4991 |
|
161 |
E |
A |
-2.3822 |
|
162 |
S |
A |
-1.2305 |
|
163 |
V |
A |
-0.8920 |
|
164 |
T |
A |
-1.2551 |
|
165 |
E |
A |
-2.3597 |
|
166 |
Q |
A |
0.0000 |
|
167 |
D |
A |
-2.7910 |
|
168 |
S |
A |
-2.4218 |
|
169 |
K |
A |
-2.6194 |
|
170 |
D |
A |
-2.2679 |
|
171 |
S |
A |
-2.3093 |
|
172 |
T |
A |
0.0000 |
|
173 |
Y |
A |
0.0000 |
|
174 |
S |
A |
-1.2467 |
|
175 |
L |
A |
0.0000 |
|
176 |
S |
A |
-0.4935 |
|
177 |
S |
A |
0.0000 |
|
178 |
T |
A |
-0.7646 |
|
179 |
L |
A |
0.0000 |
|
180 |
T |
A |
-0.5445 |
|
181 |
L |
A |
-0.8773 |
|
182 |
S |
A |
-1.5919 |
|
183 |
K |
A |
-2.6738 |
|
184 |
A |
A |
-1.9641 |
|
185 |
D |
A |
-2.9472 |
|
186 |
Y |
A |
0.0000 |
|
187 |
E |
A |
-3.5414 |
|
188 |
K |
A |
-3.6032 |
|
189 |
H |
A |
-3.0145 |
|
190 |
K |
A |
-3.2743 |
|
191 |
V |
A |
-1.7185 |
|
192 |
Y |
A |
0.0000 |
|
193 |
A |
A |
0.0000 |
|
194 |
C |
A |
0.0000 |
|
195 |
E |
A |
-0.6295 |
|
196 |
V |
A |
0.0000 |
|
197 |
T |
A |
-1.1900 |
|
198 |
H |
A |
0.0000 |
|
199 |
Q |
A |
-1.6309 |
|
200 |
G |
A |
-0.4538 |
|
201 |
L |
A |
-0.2727 |
|
202 |
S |
A |
-0.4535 |
|
203 |
S |
A |
-0.4192 |
|
204 |
P |
A |
-0.4962 |
|
205 |
V |
A |
0.0462 |
|
206 |
T |
A |
-0.3041 |
|
207 |
K |
A |
-0.3217 |
|
208 |
S |
A |
-0.3508 |
|
209 |
F |
A |
-0.9102 |
|
210 |
N |
A |
-2.0650 |
|
211 |
R |
A |
-2.4782 |
|
212 |
G |
A |
-2.0204 |
|
213 |
E |
A |
-2.5333 |
|