Project name: 10%_pg_2osl

Chain sequence(s)	A: QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8395
• Maximal score value: 1.788
• Average score: -0.6938
• Total score value: -301.8079

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.0205
2	I	A	-0.0051
3	V	A	0.9208
4	L	A	0.0000
5	S	A	-0.7425
6	Q	A	-0.9587
7	S	A	-0.4239
8	P	A	0.2811
9	A	A	0.6522
10	I	A	1.7880
11	L	A	0.8603
12	S	A	0.0428
13	A	A	0.0000
14	S	A	-1.7928
15	P	A	-2.1251
16	G	A	-2.5206
17	E	A	-3.4702
18	K	A	-3.2835
19	V	A	-1.4517
20	T	A	-0.3681
21	M	A	0.0000
22	T	A	-0.7203
23	C	A	0.0000
24	R	A	-1.9318
25	A	A	-0.7714
26	S	A	-0.4110
27	S	A	-0.5487
28	S	A	-0.6250
29	V	A	0.0000
30	S	A	-0.0862
31	Y	A	0.3698
32	I	A	0.0000
33	H	A	0.0000
34	W	A	0.0000
35	F	A	0.0000
36	Q	A	0.0000
37	Q	A	-0.7081
38	K	A	-0.9313
39	P	A	-0.9465
40	G	A	-0.7545
41	S	A	-0.7347
42	S	A	-0.5621
43	P	A	0.0000
44	K	A	-1.2009
45	P	A	-0.5331
46	W	A	-0.2158
47	I	A	0.0000
48	Y	A	0.1953
49	A	A	0.0687
50	T	A	-0.1194
51	S	A	-0.3959
52	N	A	-0.4270
53	L	A	0.4364
54	A	A	0.0000
55	S	A	-0.6511
56	G	A	-0.2948
57	V	A	0.0000
58	P	A	0.5553
59	V	A	1.5350
60	R	A	-0.3130
61	F	A	0.0000
62	S	A	0.0143
63	G	A	-0.3721
64	S	A	-0.5454
65	G	A	-0.5339
66	S	A	-0.4862
67	G	A	-0.6965
68	T	A	-0.9983
69	S	A	-1.1975
70	Y	A	0.0000
71	S	A	-0.5824
72	L	A	0.0000
73	T	A	-0.7198
74	I	A	0.0000
75	S	A	-2.1561
76	R	A	-3.6215
77	V	A	0.0000
78	E	A	-2.8352
79	A	A	0.0000
80	E	A	-3.0078
81	D	A	-1.6269
82	A	A	-1.4253
83	A	A	0.0000
84	T	A	-0.1205
85	Y	A	0.0000
86	Y	A	-0.1762
87	C	A	0.0000
88	Q	A	0.0000
89	Q	A	0.0000
90	W	A	-0.1355
91	T	A	-0.3200
92	S	A	-0.9583
93	N	A	-1.6628
94	P	A	-1.0765
95	P	A	0.0000
96	T	A	-0.0794
97	F	A	0.0000
98	G	A	0.0000
99	G	A	-1.0198
100	G	A	-0.1853
101	T	A	0.0000
102	K	A	0.2943
103	L	A	0.0000
104	E	A	-0.2754
105	I	A	0.0000
106	K	A	-1.2018
107	R	A	-0.8801
108	T	A	0.3360
109	V	A	1.1931
110	A	A	0.4068
111	A	A	0.1447
112	P	A	0.0000
113	S	A	-0.1156
114	V	A	0.1224
115	F	A	0.2091
116	I	A	0.1751
117	F	A	0.0000
118	P	A	-0.6499
119	P	A	-0.5782
120	S	A	-1.4043
121	D	A	-2.6757
122	E	A	-2.3231
123	Q	A	0.0000
124	L	A	-2.0094
125	K	A	-2.3061
126	S	A	-1.4896
127	G	A	-1.4999
128	T	A	-1.1757
129	A	A	0.0000
130	S	A	0.0000
131	V	A	0.0000
132	V	A	0.0000
133	C	A	0.0000
134	L	A	0.0000
135	L	A	0.0000
136	N	A	0.0000
137	N	A	-0.8980
138	F	A	0.0000
139	Y	A	0.0000
140	P	A	-1.2328
141	R	A	-2.1164
142	E	A	-2.9780
143	A	A	-2.2331
144	K	A	-2.2336
145	V	A	-1.0554
146	Q	A	-0.4820
147	W	A	0.0000
148	K	A	-0.6695
149	V	A	0.0000
150	D	A	-2.5158
151	N	A	-1.8454
152	A	A	-0.4432
153	L	A	0.7125
154	Q	A	0.0966
155	S	A	-0.4037
156	G	A	-0.8272
157	N	A	-0.6530
158	S	A	-0.7624
159	Q	A	-1.5265
160	E	A	-2.0237
161	S	A	-1.0135
162	V	A	-0.7305
163	T	A	0.0000
164	E	A	-2.0133
165	Q	A	-2.1120
166	D	A	-2.2567
167	S	A	-2.7307
168	K	A	-3.3480
169	D	A	-3.0889
170	S	A	0.0000
171	T	A	0.0000
172	Y	A	-1.3072
173	S	A	0.0000
174	L	A	0.0000
175	S	A	0.0000
176	S	A	0.0000
177	T	A	-0.1443
178	L	A	0.7497
179	T	A	0.3679
180	L	A	-0.2640
181	S	A	-1.3451
182	K	A	-2.4370
183	A	A	-2.1069
184	D	A	-3.1486
185	Y	A	0.0000
186	E	A	-3.8395
187	K	A	-3.8136
188	H	A	-3.0899
189	K	A	-3.1527
190	V	A	0.0000
191	Y	A	0.0000
192	A	A	0.0000
193	C	A	0.0000
194	E	A	-0.8601
195	V	A	0.0000
196	T	A	-1.1341
197	H	A	0.0000
198	Q	A	-1.6061
199	G	A	-0.1237
200	L	A	0.0945
201	S	A	-0.3341
202	S	A	-0.3266
203	P	A	-0.4197
204	V	A	0.2112
205	T	A	-0.4025
206	K	A	-0.6786
207	S	A	-0.9727
208	F	A	-1.0505
209	N	A	-2.1819
210	R	A	-2.6244
211	G	A	-2.4152
212	E	A	-2.5588
1	Q	A	-1.0650
2	V	A	-0.2406
3	Q	A	-1.0643
4	L	A	0.0000
5	Q	A	-1.3692
6	Q	A	-0.9445
7	P	A	-1.1060
8	G	A	-1.4430
9	A	A	-1.0719
10	E	A	-0.8707
11	L	A	-0.5088
12	V	A	0.0000
13	K	A	-1.8575
14	P	A	-1.6192
15	G	A	-1.0354
16	A	A	-0.8613
17	S	A	-0.9707
18	V	A	-0.8692
19	K	A	-1.3117
20	M	A	0.0000
21	S	A	-0.8047
22	C	A	0.0000
23	K	A	-1.5801
24	A	A	-0.9200
25	S	A	-0.7862
26	G	A	-0.5358
27	Y	A	-0.0860
28	T	A	-0.2475
29	F	A	0.0000
30	T	A	-0.7985
31	S	A	-0.2383
32	Y	A	0.4957
33	N	A	-0.0915
34	M	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	K	A	-0.4403
39	Q	A	-0.6754
40	T	A	-1.0774
41	P	A	-1.1105
42	G	A	-1.5792
43	R	A	-2.3690
44	G	A	-1.4893
45	L	A	0.0000
46	E	A	-0.6794
47	W	A	0.0000
48	I	A	0.0000
49	G	A	0.0000
50	A	A	-0.2464
51	I	A	0.0000
52	Y	A	-0.9020
53	P	A	0.0000
54	G	A	-1.5670
55	N	A	-2.1052
56	G	A	-1.9574
57	D	A	-2.3891
58	T	A	-1.1555
59	S	A	-0.7617
60	Y	A	-1.1086
61	N	A	0.0000
62	Q	A	-2.6952
63	K	A	-2.8449
64	F	A	-2.2148
65	K	A	-2.9921
66	G	A	-2.3210
67	K	A	-2.1855
68	A	A	0.0000
69	T	A	-0.8494
70	L	A	0.0000
71	T	A	-0.2617
72	A	A	-0.7916
73	D	A	-1.5891
74	K	A	-2.1664
75	S	A	-1.2366
76	S	A	-1.0844
77	S	A	-1.2759
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.3326
81	M	A	0.0000
82	Q	A	-1.0359
83	L	A	0.0000
84	S	A	-0.9273
85	S	A	-0.8655
86	L	A	-1.1863
87	T	A	-1.5095
88	S	A	-1.8768
89	E	A	-2.5146
90	D	A	-2.1477
91	S	A	-1.1298
92	A	A	0.0000
93	V	A	0.1385
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	S	A	0.0000
100	T	A	0.4558
101	Y	A	0.8605
102	Y	A	1.1996
103	G	A	0.0235
104	G	A	-0.3018
105	D	A	-0.3416
106	W	A	0.4080
107	Y	A	0.0000
108	F	A	0.0000
109	N	A	-0.3900
110	V	A	0.0000
111	W	A	0.0000
112	G	A	0.0000
113	A	A	-0.6494
114	G	A	-0.3481
115	T	A	0.0000
116	T	A	-0.3880
117	V	A	0.0000
118	T	A	0.0000
119	V	A	0.0000
120	S	A	-1.2204
121	A	A	-0.7235
122	A	A	-0.5172
123	S	A	-0.6908
124	T	A	-0.8279
125	K	A	-1.5459
126	G	A	-1.5105
127	P	A	0.0000
128	S	A	-0.6342
129	V	A	-0.4801
130	F	A	-0.4684
131	P	A	-0.6344
132	L	A	0.0000
133	A	A	0.0000
134	P	A	-0.8810
135	S	A	-1.4769
136	S	A	-1.7956
137	K	A	-2.2294
138	S	A	-1.2391
139	T	A	-0.9542
140	S	A	-1.1908
141	G	A	-1.0801
142	G	A	-0.8728
143	T	A	-0.6243
144	A	A	0.0000
145	A	A	0.0000
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.0000
150	V	A	0.0000
151	K	A	0.0000
152	D	A	-0.5241
153	Y	A	0.0000
154	F	A	0.0000
155	P	A	0.0000
156	E	A	-0.5768
157	P	A	-0.7472
158	V	A	-0.7929
159	T	A	-0.7930
160	V	A	-0.2428
161	S	A	-0.4719
162	W	A	0.0000
163	N	A	-0.8940
164	S	A	-0.7711
165	G	A	-0.5951
166	A	A	-0.2651
167	L	A	0.0066
168	T	A	-0.1308
169	S	A	-0.1389
170	G	A	-0.1405
171	V	A	0.1486
172	H	A	-0.3915
173	T	A	-0.2254
174	F	A	0.0000
175	P	A	-0.4750
176	A	A	0.1914
177	V	A	0.5079
178	L	A	1.3844
179	Q	A	0.2808
180	S	A	-0.0817
181	S	A	-0.2028
182	G	A	0.0708
183	L	A	0.1277
184	Y	A	0.5010
185	S	A	0.0000
186	L	A	0.0844
187	S	A	0.0000
188	S	A	0.0000
189	V	A	0.0000
190	V	A	0.0000
191	T	A	-0.1749
192	V	A	0.0000
193	P	A	-0.5886
194	S	A	-0.9426
195	S	A	-0.9857
196	S	A	-0.8232
197	L	A	0.0000
198	G	A	-1.3570
199	T	A	-0.9289
200	Q	A	-1.6188
201	T	A	-1.2647
202	Y	A	0.0000
203	I	A	-1.2810
204	C	A	0.0000
205	N	A	-1.7724
206	V	A	0.0000
207	N	A	-1.9904
208	H	A	0.0000
209	K	A	-2.6080
210	P	A	-1.7325
211	S	A	-1.9350
212	N	A	-2.4640
213	T	A	-1.8438
214	K	A	-2.6005
215	V	A	-1.4158
216	D	A	-2.5235
217	K	A	-1.9832
218	K	A	-2.5112
219	V	A	0.0000
220	E	A	-2.7243
221	P	A	-1.8980
222	K	A	-2.0798
223	S	A	-1.3562