Project name: SOD1 mutations

Chain sequence(s)	B: ETCPIFYDVFFAVANGNELLLDLSLTKVNATEPERTAMKKIQDCYVENGLISRVLDGLVMTTISSSKDCMEICPAVKRDVDLFLTGTPDEYVEQVAQYKALPVVLENARILKNCVDAKMTEEDKENALSLLDKIYTSPLCLE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5415
• Maximal score value: 3.2063
• Average score: -0.6446
• Total score value: -91.5323

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
5	E	B	-2.0320
6	T	B	-1.3510
7	C	B	0.0000
8	P	B	-1.1203
9	I	B	0.0000
10	F	B	0.0000
11	Y	B	-0.2717
12	D	B	-0.6571
13	V	B	0.0000
14	F	B	0.4455
15	F	B	1.1337
16	A	B	0.0000
17	V	B	0.0000
18	A	B	0.0000
19	N	B	-0.4665
20	G	B	-0.7757
21	N	B	-0.8655
22	E	B	-1.4575
23	L	B	1.0466
24	L	B	1.0073
25	L	B	0.0000
26	D	B	-0.1366
27	L	B	0.7075
28	S	B	0.0000
29	L	B	0.0000
30	T	B	-1.1618
31	K	B	-1.8626
32	V	B	0.0000
33	N	B	-2.1185
34	A	B	-1.6935
35	T	B	-1.4422
36	E	B	-2.2398
37	P	B	-1.8770
38	E	B	0.0000
39	R	B	-1.6380
40	T	B	-1.1642
41	A	B	0.0000
42	M	B	0.0000
43	K	B	-1.8171
44	K	B	-1.3107
45	I	B	0.0000
46	Q	B	0.0000
47	D	B	-2.0975
48	C	B	0.0000
49	Y	B	0.0000
50	V	B	-0.0900
51	E	B	-1.4633
52	N	B	-0.2378
53	G	B	0.9215
54	L	B	2.5546
55	I	B	3.2063
56	S	B	0.0000
57	R	B	1.6736
58	V	B	2.6862
59	L	B	2.0122
60	D	B	0.0000
61	G	B	1.1696
62	L	B	0.9856
63	V	B	0.0000
64	M	B	0.0000
65	T	B	0.0919
66	T	B	-0.1733
67	I	B	0.0000
68	S	B	-0.5624
69	S	B	-0.7194
70	S	B	-1.2446
71	K	B	-2.2780
72	D	B	-2.3071
73	C	B	-0.9240
74	M	B	-0.0281
93	E	B	-1.9375
94	I	B	0.0000
95	C	B	0.0000
96	P	B	-1.6162
97	A	B	-1.5210
98	V	B	0.0000
99	K	B	-2.3914
100	R	B	-2.6729
101	D	B	0.0000
102	V	B	-1.1793
103	D	B	-1.6849
104	L	B	0.0000
105	F	B	0.0000
106	L	B	0.0000
107	T	B	-1.1107
108	G	B	-1.3760
109	T	B	-1.7476
110	P	B	-2.4916
111	D	B	-3.3980
112	E	B	-3.1046
113	Y	B	0.0000
114	V	B	0.0000
115	E	B	-3.2899
116	Q	B	0.0000
117	V	B	0.0000
118	A	B	-0.9523
119	Q	B	-1.5777
120	Y	B	-0.5327
121	K	B	-0.1659
122	A	B	0.0721
123	L	B	1.4661
124	P	B	0.5072
125	V	B	0.6062
126	V	B	0.0000
127	L	B	-0.6116
128	E	B	-1.4666
129	N	B	0.0000
130	A	B	0.0000
131	R	B	-2.3737
132	I	B	-0.7346
133	L	B	0.0000
134	K	B	0.0000
135	N	B	-1.8523
136	C	B	-1.5538
137	V	B	0.0000
138	D	B	-2.0269
139	A	B	-1.2524
140	K	B	-1.7952
141	M	B	0.0000
142	T	B	-2.3306
143	E	B	-3.5415
144	E	B	-3.5068
145	D	B	0.0000
146	K	B	-2.7321
147	E	B	-3.0845
148	N	B	-2.3809
149	A	B	0.0000
150	L	B	-1.0931
151	S	B	-1.2195
152	L	B	0.0000
153	L	B	0.0000
154	D	B	-2.0456
155	K	B	-1.6988
156	I	B	0.0000
157	Y	B	-0.9686
158	T	B	-0.8220
159	S	B	0.0000
160	P	B	-0.4227
161	L	B	0.0198
162	C	B	0.0000
163	L	B	-0.4852
164	E	B	-1.5118