Project name: 4ojf:H
Status: done
submitted: 2019-03-21 14:47:41, status changed: 2019-03-21 14:56:40
Settings
Chain sequence(s)
|
H: VQLLESGGGLVQPGGSLRLSCAASGFTFSNYGMSWVRQAPGKGLEWVASIRSGGGRTYYSDNVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCVRYDHYSGSSDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPQPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8406
-
Maximal score value
-
2.4201
-
Average score
-
-0.5746
-
Total score value
-
-125.8358
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
2 |
V |
H |
1.3523 |
|
3 |
Q |
H |
0.2054 |
|
4 |
L |
H |
0.0000 |
|
5 |
L |
H |
0.5613 |
|
6 |
E |
H |
0.0000 |
|
7 |
S |
H |
-0.5397 |
|
8 |
G |
H |
-0.9557 |
|
9 |
G |
H |
-0.7572 |
|
10 |
G |
H |
-0.5825 |
|
11 |
L |
H |
-0.1767 |
|
12 |
V |
H |
0.0000 |
|
13 |
Q |
H |
-1.6060 |
|
14 |
P |
H |
-1.6470 |
|
15 |
G |
H |
-1.3137 |
|
16 |
G |
H |
0.0000 |
|
17 |
S |
H |
-1.2520 |
|
18 |
L |
H |
-1.1618 |
|
19 |
R |
H |
-2.0736 |
|
20 |
L |
H |
0.0000 |
|
21 |
S |
H |
-0.4801 |
|
22 |
C |
H |
0.0000 |
|
23 |
A |
H |
-0.2416 |
|
24 |
A |
H |
0.0000 |
|
25 |
S |
H |
0.0085 |
|
26 |
G |
H |
0.1133 |
|
27 |
F |
H |
0.0800 |
|
28 |
T |
H |
-0.3973 |
|
29 |
F |
H |
0.0000 |
|
30 |
S |
H |
-1.3334 |
|
31 |
N |
H |
-1.6792 |
|
32 |
Y |
H |
-0.9917 |
|
33 |
G |
H |
0.0000 |
|
34 |
M |
H |
0.0000 |
|
35 |
S |
H |
0.1136 |
|
36 |
W |
H |
0.0000 |
|
37 |
V |
H |
0.6626 |
|
38 |
R |
H |
0.0000 |
|
39 |
Q |
H |
-0.3853 |
|
40 |
A |
H |
-1.0428 |
|
41 |
P |
H |
-1.0993 |
|
42 |
G |
H |
-1.5671 |
|
43 |
K |
H |
-2.0634 |
|
44 |
G |
H |
-0.9122 |
|
45 |
L |
H |
0.7555 |
|
46 |
E |
H |
0.0723 |
|
47 |
W |
H |
0.3142 |
|
48 |
V |
H |
0.0000 |
|
49 |
A |
H |
0.0000 |
|
50 |
S |
H |
-0.3836 |
|
51 |
I |
H |
0.0000 |
|
52 |
R |
H |
-2.8253 |
|
52A |
S |
H |
-2.0365 |
|
53 |
G |
H |
-1.9303 |
|
54 |
G |
H |
-1.8414 |
|
55 |
G |
H |
-2.2446 |
|
56 |
R |
H |
-2.7671 |
|
57 |
T |
H |
-1.2356 |
|
58 |
Y |
H |
-0.2801 |
|
59 |
Y |
H |
-0.6662 |
|
60 |
S |
H |
-1.5114 |
|
61 |
D |
H |
-2.8282 |
|
62 |
N |
H |
-2.8406 |
|
63 |
V |
H |
0.0000 |
|
64 |
K |
H |
-2.7919 |
|
65 |
G |
H |
-1.9200 |
|
66 |
R |
H |
-1.6534 |
|
67 |
F |
H |
0.0000 |
|
68 |
T |
H |
-0.7209 |
|
69 |
I |
H |
0.0000 |
|
70 |
S |
H |
-0.8735 |
|
71 |
R |
H |
-1.2482 |
|
72 |
D |
H |
-1.4949 |
|
73 |
N |
H |
-1.8357 |
|
74 |
A |
H |
-1.4088 |
|
75 |
K |
H |
-2.2814 |
|
76 |
N |
H |
-1.7080 |
|
77 |
S |
H |
0.0000 |
|
78 |
L |
H |
0.0000 |
|
79 |
Y |
H |
-0.4612 |
|
80 |
L |
H |
0.0000 |
|
81 |
Q |
H |
-1.1314 |
|
82 |
M |
H |
0.0000 |
|
82A |
N |
H |
-1.4602 |
|
82B |
S |
H |
-1.2217 |
|
82C |
L |
H |
0.0000 |
|
83 |
R |
H |
-2.2123 |
|
84 |
A |
H |
-1.6775 |
|
85 |
E |
H |
-2.3339 |
|
86 |
D |
H |
0.0000 |
|
87 |
T |
H |
-0.7671 |
|
88 |
A |
H |
0.0000 |
|
89 |
L |
H |
0.3101 |
|
90 |
Y |
H |
0.0000 |
|
91 |
Y |
H |
0.5299 |
|
92 |
C |
H |
0.0000 |
|
93 |
V |
H |
0.0000 |
|
94 |
R |
H |
0.0000 |
|
95 |
Y |
H |
-0.1586 |
|
96 |
D |
H |
0.0000 |
|
97 |
H |
H |
-0.5871 |
|
98 |
Y |
H |
0.7025 |
|
99 |
S |
H |
-0.1695 |
|
100 |
G |
H |
-0.5946 |
|
100A |
S |
H |
-0.4676 |
|
100B |
S |
H |
-0.3634 |
|
101 |
D |
H |
-0.3405 |
|
102 |
Y |
H |
0.9285 |
|
103 |
W |
H |
0.7375 |
|
104 |
G |
H |
0.1857 |
|
105 |
Q |
H |
-0.8664 |
|
106 |
G |
H |
0.0000 |
|
107 |
T |
H |
-0.1234 |
|
108 |
L |
H |
-0.0473 |
|
109 |
V |
H |
0.0000 |
|
110 |
T |
H |
-0.4859 |
|
111 |
V |
H |
0.0000 |
|
112 |
S |
H |
-0.9577 |
|
113 |
S |
H |
-0.6589 |
|
114 |
A |
H |
-0.4632 |
|
115 |
S |
H |
-0.6056 |
|
116 |
T |
H |
-0.6457 |
|
117 |
K |
H |
-1.2364 |
|
118 |
G |
H |
-1.4394 |
|
119 |
P |
H |
-0.5504 |
|
120 |
S |
H |
-0.0814 |
|
121 |
V |
H |
0.0000 |
|
122 |
F |
H |
1.0937 |
|
123 |
P |
H |
0.1943 |
|
124 |
L |
H |
0.4101 |
|
125 |
A |
H |
-0.6160 |
|
126 |
P |
H |
-0.9995 |
|
127 |
S |
H |
-1.1337 |
|
128 |
S |
H |
-1.7521 |
|
129 |
K |
H |
-2.0923 |
|
130 |
S |
H |
-1.5305 |
|
131 |
T |
H |
-0.9706 |
|
132 |
S |
H |
-0.7910 |
|
133 |
G |
H |
-0.7944 |
|
134 |
G |
H |
-0.7718 |
|
135 |
T |
H |
-0.5658 |
|
136 |
A |
H |
-0.5276 |
|
137 |
A |
H |
0.1003 |
|
138 |
L |
H |
0.0000 |
|
139 |
G |
H |
0.0000 |
|
140 |
C |
H |
0.0000 |
|
141 |
L |
H |
0.7661 |
|
142 |
V |
H |
0.0000 |
|
143 |
K |
H |
-0.2120 |
|
144 |
D |
H |
-0.3923 |
|
145 |
Y |
H |
0.0000 |
|
146 |
F |
H |
0.0000 |
|
147 |
P |
H |
0.0000 |
|
148 |
Q |
H |
-0.3093 |
|
149 |
P |
H |
-0.5477 |
|
150 |
V |
H |
-0.5249 |
|
151 |
T |
H |
-0.4510 |
|
152 |
V |
H |
-0.1391 |
|
153 |
S |
H |
-0.4394 |
|
154 |
W |
H |
0.0000 |
|
155 |
N |
H |
-0.7762 |
|
156 |
S |
H |
-0.6950 |
|
157 |
G |
H |
-0.5293 |
|
158 |
A |
H |
-0.2471 |
|
159 |
L |
H |
-0.0343 |
|
160 |
T |
H |
-0.2979 |
|
161 |
S |
H |
-0.3689 |
|
162 |
G |
H |
-0.4582 |
|
163 |
V |
H |
0.0273 |
|
164 |
H |
H |
-0.4342 |
|
165 |
T |
H |
0.1919 |
|
166 |
F |
H |
0.9429 |
|
167 |
P |
H |
0.7270 |
|
168 |
A |
H |
1.2893 |
|
169 |
V |
H |
2.4201 |
|
170 |
L |
H |
2.0376 |
|
171 |
Q |
H |
0.6462 |
|
172 |
S |
H |
0.0687 |
|
173 |
S |
H |
-0.2132 |
|
174 |
G |
H |
0.2027 |
|
175 |
L |
H |
0.2996 |
|
176 |
Y |
H |
0.8762 |
|
177 |
S |
H |
0.0000 |
|
178 |
L |
H |
0.0000 |
|
179 |
S |
H |
0.6728 |
|
180 |
S |
H |
0.0000 |
|
181 |
V |
H |
0.4626 |
|
182 |
V |
H |
0.0000 |
|
183 |
T |
H |
-0.2158 |
|
184 |
V |
H |
0.0000 |
|
185 |
P |
H |
-0.4229 |
|
186 |
S |
H |
-0.6670 |
|
187 |
S |
H |
-0.5172 |
|
188 |
S |
H |
-0.5776 |
|
189 |
L |
H |
-0.6043 |
|
190 |
G |
H |
-0.9453 |
|
191 |
T |
H |
-0.7835 |
|
192 |
Q |
H |
-1.2060 |
|
193 |
T |
H |
-1.0968 |
|
194 |
Y |
H |
0.0000 |
|
195 |
I |
H |
-1.3347 |
|
196 |
C |
H |
0.0000 |
|
197 |
N |
H |
-1.4142 |
|
198 |
V |
H |
0.0000 |
|
199 |
N |
H |
-1.7324 |
|
200 |
H |
H |
0.0000 |
|
201 |
K |
H |
-2.7133 |
|
202 |
P |
H |
-1.5473 |
|
203 |
S |
H |
-1.8111 |
|
204 |
N |
H |
-2.5020 |
|
205 |
T |
H |
-2.0521 |
|
206 |
K |
H |
-2.5944 |
|
207 |
V |
H |
-1.4645 |
|
208 |
D |
H |
-2.4586 |
|
209 |
K |
H |
-1.8037 |
|
210 |
K |
H |
-2.2033 |
|
211 |
V |
H |
0.0000 |
|
212 |
E |
H |
-2.6093 |
|
213 |
P |
H |
-2.0587 |
|
214 |
K |
H |
-2.2519 |
|