Project name: 5xhg:A
Status: done
submitted: 2019-03-21 14:58:49, status changed: 2019-03-21 15:08:41
Settings
Chain sequence(s)
|
A: DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSSRFSGSSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALKSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSSPVTKSFNRGE
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5422
-
Maximal score value
-
2.4494
-
Average score
-
-0.7936
-
Total score value
-
-169.0323
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
D |
A |
-2.2925 |
|
2 |
I |
A |
0.0000 |
|
3 |
Q |
A |
-2.1337 |
|
4 |
M |
A |
0.0000 |
|
5 |
T |
A |
-1.2917 |
|
6 |
Q |
A |
0.0000 |
|
7 |
S |
A |
-0.8927 |
|
8 |
P |
A |
-0.6078 |
|
9 |
S |
A |
-0.8308 |
|
10 |
S |
A |
-0.6878 |
|
11 |
L |
A |
-0.5000 |
|
12 |
S |
A |
-0.7649 |
|
13 |
A |
A |
-0.9540 |
|
14 |
S |
A |
-0.8210 |
|
15 |
V |
A |
-0.0784 |
|
16 |
G |
A |
-0.6261 |
|
17 |
D |
A |
-1.7555 |
|
18 |
R |
A |
-2.2813 |
|
19 |
V |
A |
0.0000 |
|
20 |
T |
A |
-0.6370 |
|
21 |
I |
A |
0.0000 |
|
22 |
T |
A |
-0.7525 |
|
23 |
C |
A |
0.0000 |
|
24 |
R |
A |
-2.7318 |
|
25 |
A |
A |
0.0000 |
|
26 |
S |
A |
-2.0566 |
|
27 |
Q |
A |
-2.5143 |
|
28 |
D |
A |
-2.2664 |
|
29 |
V |
A |
0.0000 |
|
30 |
N |
A |
-1.8814 |
|
31 |
T |
A |
-0.9968 |
|
32 |
A |
A |
-0.4217 |
|
33 |
V |
A |
0.0000 |
|
34 |
A |
A |
0.6283 |
|
35 |
W |
A |
0.0000 |
|
36 |
Y |
A |
0.0908 |
|
37 |
Q |
A |
0.0000 |
|
38 |
Q |
A |
-1.4756 |
|
39 |
K |
A |
-2.1409 |
|
40 |
P |
A |
-1.5530 |
|
41 |
G |
A |
-1.5669 |
|
42 |
K |
A |
-2.4140 |
|
43 |
A |
A |
-1.4132 |
|
44 |
P |
A |
-1.2918 |
|
45 |
K |
A |
-1.3298 |
|
46 |
L |
A |
0.0673 |
|
47 |
L |
A |
0.0000 |
|
48 |
I |
A |
0.0000 |
|
49 |
Y |
A |
1.6251 |
|
50 |
S |
A |
0.4626 |
|
51 |
A |
A |
0.0000 |
|
52 |
S |
A |
0.8142 |
|
53 |
F |
A |
2.4494 |
|
54 |
L |
A |
1.8464 |
|
55 |
Y |
A |
1.3423 |
|
56 |
S |
A |
0.3073 |
|
57 |
G |
A |
-0.3147 |
|
58 |
V |
A |
0.0000 |
|
59 |
P |
A |
-0.2855 |
|
60 |
S |
A |
-0.3339 |
|
61 |
R |
A |
-0.7527 |
|
62 |
F |
A |
0.0000 |
|
63 |
S |
A |
0.1607 |
|
64 |
G |
A |
0.1231 |
|
65 |
S |
A |
-0.6609 |
|
66 |
R |
A |
-1.7074 |
|
67 |
S |
A |
-1.3745 |
|
68 |
G |
A |
-1.7448 |
|
69 |
T |
A |
-2.0561 |
|
70 |
D |
A |
-1.8978 |
|
71 |
F |
A |
0.0000 |
|
72 |
T |
A |
-0.7829 |
|
73 |
L |
A |
0.0000 |
|
74 |
T |
A |
-0.6353 |
|
75 |
I |
A |
0.0000 |
|
76 |
S |
A |
-1.3995 |
|
77 |
S |
A |
-1.0954 |
|
78 |
L |
A |
0.0000 |
|
79 |
Q |
A |
-0.8231 |
|
80 |
P |
A |
-1.5290 |
|
81 |
E |
A |
-2.2193 |
|
82 |
D |
A |
0.0000 |
|
83 |
F |
A |
-1.2473 |
|
84 |
A |
A |
0.0000 |
|
85 |
T |
A |
-0.8712 |
|
86 |
Y |
A |
0.0000 |
|
87 |
Y |
A |
-0.0049 |
|
88 |
C |
A |
0.0000 |
|
89 |
Q |
A |
0.1578 |
|
90 |
Q |
A |
0.0000 |
|
91 |
H |
A |
-0.5689 |
|
92 |
Y |
A |
0.0881 |
|
93 |
T |
A |
-0.2121 |
|
94 |
T |
A |
-0.5375 |
|
95 |
P |
A |
-0.5577 |
|
96 |
P |
A |
-0.5543 |
|
97 |
T |
A |
-0.3475 |
|
98 |
F |
A |
0.6058 |
|
99 |
G |
A |
0.0000 |
|
100 |
Q |
A |
-1.1851 |
|
101 |
G |
A |
0.0000 |
|
102 |
T |
A |
0.0000 |
|
103 |
K |
A |
-1.4284 |
|
104 |
V |
A |
0.0000 |
|
105 |
E |
A |
-1.0690 |
|
106 |
I |
A |
0.0000 |
|
107 |
K |
A |
-1.4006 |
|
108 |
R |
A |
-0.8621 |
|
109 |
T |
A |
-0.1828 |
|
110 |
V |
A |
0.1238 |
|
111 |
A |
A |
-0.2751 |
|
112 |
A |
A |
-0.2719 |
|
113 |
P |
A |
0.0000 |
|
114 |
S |
A |
-0.1678 |
|
115 |
V |
A |
0.0000 |
|
116 |
F |
A |
1.2161 |
|
117 |
I |
A |
1.2216 |
|
118 |
F |
A |
1.4416 |
|
119 |
P |
A |
0.0763 |
|
120 |
P |
A |
-0.6975 |
|
121 |
S |
A |
-1.8245 |
|
122 |
D |
A |
-3.2495 |
|
123 |
E |
A |
-3.4438 |
|
124 |
Q |
A |
-2.5014 |
|
125 |
L |
A |
-2.5361 |
|
126 |
K |
A |
-3.0402 |
|
127 |
S |
A |
-1.8952 |
|
128 |
G |
A |
-1.3384 |
|
129 |
T |
A |
-1.3698 |
|
130 |
A |
A |
0.0000 |
|
131 |
S |
A |
0.0150 |
|
132 |
V |
A |
0.0000 |
|
133 |
V |
A |
0.6735 |
|
134 |
C |
A |
0.0000 |
|
135 |
L |
A |
0.4435 |
|
136 |
L |
A |
0.0000 |
|
137 |
N |
A |
-0.6019 |
|
138 |
N |
A |
-1.3428 |
|
139 |
F |
A |
0.0000 |
|
140 |
Y |
A |
0.0000 |
|
141 |
P |
A |
-1.7153 |
|
142 |
R |
A |
-2.8250 |
|
143 |
E |
A |
-3.0997 |
|
144 |
A |
A |
-2.3016 |
|
145 |
K |
A |
-2.3988 |
|
146 |
V |
A |
-1.1017 |
|
147 |
Q |
A |
-0.5838 |
|
148 |
W |
A |
0.0000 |
|
149 |
K |
A |
-0.6722 |
|
150 |
V |
A |
0.0000 |
|
151 |
D |
A |
-1.9731 |
|
152 |
N |
A |
-1.5884 |
|
153 |
A |
A |
-0.3868 |
|
154 |
L |
A |
0.6012 |
|
155 |
K |
A |
-0.5802 |
|
156 |
S |
A |
-0.6021 |
|
157 |
G |
A |
-1.1562 |
|
158 |
N |
A |
-1.1992 |
|
159 |
S |
A |
-1.5298 |
|
160 |
Q |
A |
-2.3238 |
|
161 |
E |
A |
-2.3621 |
|
162 |
S |
A |
-1.3728 |
|
163 |
V |
A |
-0.8230 |
|
164 |
T |
A |
-1.2874 |
|
165 |
E |
A |
-2.3073 |
|
166 |
Q |
A |
0.0000 |
|
167 |
D |
A |
-2.5762 |
|
168 |
S |
A |
-2.3235 |
|
169 |
K |
A |
-2.6189 |
|
170 |
D |
A |
-1.9131 |
|
171 |
S |
A |
-1.9255 |
|
172 |
T |
A |
0.0000 |
|
173 |
Y |
A |
0.0000 |
|
174 |
S |
A |
-1.0368 |
|
175 |
L |
A |
0.0000 |
|
176 |
S |
A |
-0.5427 |
|
177 |
S |
A |
0.0000 |
|
178 |
T |
A |
-0.6669 |
|
179 |
L |
A |
0.0000 |
|
180 |
T |
A |
-0.5617 |
|
181 |
L |
A |
-0.7552 |
|
182 |
S |
A |
-1.0935 |
|
183 |
K |
A |
-2.1379 |
|
184 |
A |
A |
-1.8828 |
|
185 |
D |
A |
-2.6377 |
|
186 |
Y |
A |
0.0000 |
|
187 |
E |
A |
-3.3898 |
|
188 |
K |
A |
-3.5422 |
|
189 |
H |
A |
-2.7649 |
|
190 |
K |
A |
-2.7476 |
|
191 |
V |
A |
-1.1986 |
|
192 |
Y |
A |
0.0000 |
|
193 |
A |
A |
0.0000 |
|
194 |
C |
A |
0.0000 |
|
195 |
E |
A |
-0.9165 |
|
196 |
V |
A |
0.0000 |
|
197 |
T |
A |
-1.2362 |
|
198 |
H |
A |
0.0000 |
|
199 |
Q |
A |
-1.7276 |
|
200 |
G |
A |
-0.4528 |
|
201 |
L |
A |
-0.2292 |
|
202 |
S |
A |
-0.4401 |
|
203 |
S |
A |
-0.4265 |
|
204 |
P |
A |
-0.5853 |
|
205 |
V |
A |
-0.0943 |
|
206 |
T |
A |
-0.4026 |
|
207 |
K |
A |
-0.3137 |
|
208 |
S |
A |
-0.2241 |
|
209 |
F |
A |
-0.6006 |
|
210 |
N |
A |
-1.7159 |
|
211 |
R |
A |
-2.1871 |
|
212 |
G |
A |
-1.9767 |
|
213 |
E |
A |
-2.4191 |
|