Project name: sona

Chain sequence(s)	A: AKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKLDARKIREILIKAKK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5045
• Maximal score value: 2.0754
• Average score: -0.7218
• Total score value: -377.5011

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
4	A	A	-0.8234
5	K	A	-1.8571
6	N	A	-1.1422
7	I	A	-0.9437
8	K	A	0.0000
9	K	A	-2.1869
10	G	A	-1.0511
11	P	A	-0.3066
12	A	A	0.2841
13	P	A	1.2015
14	F	A	2.0754
15	Y	A	1.1292
16	P	A	0.2342
17	L	A	-0.2331
18	E	A	-1.7790
19	D	A	-2.3932
20	G	A	-1.7557
21	T	A	0.0000
22	A	A	0.0000
23	G	A	0.0000
24	E	A	-0.8255
25	Q	A	-1.1353
26	L	A	0.0000
27	H	A	0.0000
28	K	A	-1.6497
29	A	A	0.0000
30	M	A	0.0000
31	K	A	-0.9953
32	R	A	-1.3276
33	Y	A	0.1552
34	A	A	0.0000
35	L	A	1.7352
36	V	A	2.0004
37	P	A	0.7416
38	G	A	-0.0235
39	T	A	0.1224
40	I	A	-0.2052
41	A	A	0.0000
42	F	A	0.0000
43	T	A	0.0000
44	D	A	0.0000
45	A	A	0.0000
46	H	A	0.2007
47	I	A	1.2677
48	E	A	-0.4729
49	V	A	0.6614
50	N	A	-0.2749
51	I	A	-0.1964
52	T	A	-0.3801
53	Y	A	0.0000
54	A	A	-0.4059
55	E	A	-1.5237
56	Y	A	0.0000
57	F	A	0.0000
58	E	A	-1.3638
59	M	A	0.0000
60	S	A	0.0000
61	V	A	0.0000
62	R	A	-1.0753
63	L	A	0.0000
64	A	A	0.0000
65	E	A	0.0000
66	A	A	0.0000
67	M	A	0.0000
68	K	A	-2.2099
69	R	A	-2.3790
70	Y	A	-1.1891
71	G	A	-1.4522
72	L	A	0.0000
73	N	A	-1.8824
74	T	A	-1.4330
75	N	A	-1.7047
76	H	A	-1.3493
77	R	A	-0.9119
78	I	A	0.0000
79	V	A	0.0000
80	V	A	0.0000
81	C	A	0.0000
82	S	A	0.0000
83	E	A	-0.4433
84	N	A	0.0000
85	S	A	-0.1614
86	L	A	0.0000
87	Q	A	-0.3383
88	F	A	0.0000
89	F	A	0.0000
90	M	A	0.0000
91	P	A	0.0000
92	V	A	0.0000
93	L	A	0.0000
94	G	A	0.0000
95	A	A	0.0000
96	L	A	0.0000
97	F	A	0.0000
98	I	A	0.0000
99	G	A	0.0000
100	V	A	0.0000
101	A	A	0.0000
102	V	A	0.0000
103	A	A	0.0000
104	P	A	0.0000
105	A	A	0.0000
106	N	A	-0.2369
107	D	A	-0.1701
108	I	A	1.2270
109	Y	A	-0.6008
110	N	A	-2.1246
111	E	A	-2.9303
112	R	A	-3.3281
113	E	A	-2.0791
114	L	A	0.0000
115	L	A	-2.0779
116	N	A	-1.1918
117	S	A	0.0000
118	M	A	0.0000
119	N	A	-1.6336
120	I	A	-0.8055
121	S	A	0.0000
122	Q	A	-0.6635
123	P	A	0.0000
124	T	A	0.0000
125	V	A	0.0000
126	V	A	0.0000
127	F	A	0.0000
128	V	A	0.0000
129	S	A	0.0000
130	K	A	-1.8950
131	K	A	-2.4273
132	G	A	0.0000
133	L	A	0.0000
134	Q	A	-1.8932
135	K	A	-1.9568
136	I	A	0.0000
137	L	A	-1.1980
138	N	A	-1.9351
139	V	A	0.0000
140	Q	A	-2.0318
141	K	A	-2.6767
142	K	A	-2.7616
143	L	A	0.0000
144	P	A	-1.1249
145	I	A	-0.5250
146	I	A	0.0000
147	Q	A	-1.2728
148	K	A	-0.8334
149	I	A	0.0000
150	I	A	0.0000
151	I	A	0.0000
152	M	A	0.0000
153	D	A	-1.1740
154	S	A	-1.4940
155	K	A	-2.1310
156	T	A	-1.8552
157	D	A	-2.3668
158	Y	A	-1.6715
159	Q	A	-1.6952
160	G	A	-1.2861
161	F	A	-0.8423
162	Q	A	-1.2526
163	S	A	0.0000
164	M	A	0.0000
165	Y	A	-0.6377
166	T	A	-0.7372
167	F	A	0.0000
168	V	A	0.0000
169	T	A	-0.2582
170	S	A	-0.4700
171	H	A	-1.0134
172	L	A	-0.8266
173	P	A	-0.7088
174	P	A	-0.5521
175	G	A	-0.7543
176	F	A	-0.9331
177	N	A	-1.8417
178	E	A	-1.2573
179	Y	A	-0.6297
180	D	A	-1.5410
181	F	A	0.0000
182	V	A	0.8557
183	P	A	-0.1572
184	E	A	-1.0041
185	S	A	-0.7323
186	F	A	-1.1679
187	D	A	-2.0829
188	R	A	-2.2326
189	D	A	-2.6135
190	K	A	-2.6812
191	T	A	-1.6392
192	I	A	-0.7407
193	A	A	0.0000
194	L	A	0.0000
195	I	A	0.0000
196	M	A	0.0000
197	N	A	-0.6379
198	S	A	-0.2907
204	L	A	1.2306
205	P	A	0.1970
206	K	A	-0.4536
207	G	A	0.0000
208	V	A	0.0000
209	A	A	0.0000
210	L	A	0.0000
211	P	A	0.0000
212	H	A	0.0000
213	R	A	-1.4704
214	T	A	0.0000
215	A	A	0.0000
216	C	A	0.0000
217	V	A	0.0000
218	R	A	0.0000
219	F	A	0.0000
220	S	A	0.0000
221	H	A	0.0000
222	A	A	0.0000
223	R	A	0.0000
224	D	A	0.0000
225	P	A	-0.0550
226	I	A	0.0772
227	F	A	0.0000
228	G	A	-0.4306
229	N	A	-0.4606
230	Q	A	-0.1182
231	I	A	0.6680
232	I	A	1.3808
233	P	A	-0.1859
234	D	A	-1.5441
235	T	A	0.0000
236	A	A	0.0000
237	I	A	0.0000
238	L	A	0.0000
239	S	A	0.0000
240	V	A	0.0570
241	V	A	0.0000
242	P	A	-0.2192
243	F	A	0.0000
244	H	A	-0.6307
245	H	A	-0.8353
246	G	A	-0.3672
247	F	A	-0.0196
248	G	A	0.0000
249	M	A	0.0000
250	F	A	0.0000
251	T	A	0.0199
252	T	A	0.0000
253	L	A	0.0000
254	G	A	0.0000
255	Y	A	0.0000
256	L	A	0.0000
257	I	A	0.0000
258	C	A	0.0000
259	G	A	-0.2313
260	F	A	0.0000
261	R	A	-0.7092
262	V	A	0.0000
263	V	A	0.0000
264	L	A	0.0000
265	M	A	0.0000
266	Y	A	-0.5209
267	R	A	-1.6913
268	F	A	-1.0068
269	E	A	-1.9816
270	E	A	-1.9163
271	E	A	-2.4361
272	L	A	-1.8968
273	F	A	0.0000
274	L	A	0.0000
275	R	A	-3.1010
276	S	A	0.0000
277	L	A	0.0000
278	Q	A	-2.4051
279	D	A	-2.0672
280	Y	A	-1.3217
281	K	A	-2.3052
282	I	A	0.0000
283	Q	A	-1.2938
284	S	A	0.0000
285	A	A	0.0000
286	L	A	0.0000
287	L	A	0.0000
288	V	A	0.5701
289	P	A	0.2152
290	T	A	0.2940
291	L	A	0.3780
292	F	A	0.0000
293	S	A	-0.1935
294	F	A	0.1581
295	F	A	0.0000
296	A	A	-1.4702
297	K	A	-1.5832
298	S	A	0.0000
299	T	A	-1.0675
300	L	A	-1.3664
301	I	A	0.0000
302	D	A	-3.0359
303	K	A	-2.9980
304	Y	A	-2.7951
305	D	A	-3.0763
306	L	A	-2.2932
307	S	A	-1.3156
308	N	A	-1.5348
309	L	A	0.0000
310	H	A	-1.4149
311	E	A	-0.8797
312	I	A	0.0000
313	A	A	0.0000
314	S	A	0.0000
315	G	A	-0.0664
316	G	A	-0.0552
317	A	A	0.0005
318	P	A	-0.1637
319	L	A	-0.7069
320	S	A	-1.5709
321	K	A	-2.7579
322	E	A	-3.0158
323	V	A	-1.7013
324	G	A	0.0000
325	E	A	-3.5045
326	A	A	-2.6663
327	V	A	0.0000
328	A	A	0.0000
329	K	A	-2.9993
330	R	A	-2.7562
331	F	A	0.0000
332	H	A	-2.3985
333	L	A	-1.5456
334	P	A	-1.2624
335	G	A	-1.6120
336	I	A	-0.8174
337	R	A	-0.5121
338	Q	A	0.0000
339	G	A	0.0000
340	Y	A	0.0000
341	G	A	-0.0026
342	L	A	0.2074
343	T	A	-0.1437
344	E	A	0.0000
345	T	A	0.0000
346	T	A	0.0000
347	S	A	-0.0591
348	A	A	0.0000
349	I	A	0.0000
350	L	A	0.0000
351	I	A	0.0000
352	T	A	-0.6600
353	P	A	-0.9565
354	E	A	-1.8215
355	G	A	-1.2629
359	P	A	-1.1348
360	G	A	-1.1153
361	A	A	-0.4056
362	V	A	0.0000
363	G	A	0.0000
364	K	A	-1.2206
365	V	A	0.0000
366	V	A	0.0000
367	P	A	0.0000
368	F	A	0.0783
369	F	A	0.0000
370	E	A	-1.0787
371	A	A	0.0000
372	K	A	-0.9359
373	V	A	0.0000
374	V	A	0.0000
375	D	A	-2.0527
376	L	A	-1.5688
377	D	A	-2.1438
378	T	A	-1.6741
379	G	A	-1.7848
380	K	A	-2.2811
381	T	A	-1.2380
382	L	A	0.0000
383	G	A	-1.1651
384	V	A	-1.1285
385	N	A	-1.8684
386	Q	A	-1.9976
387	R	A	-2.0679
388	G	A	0.0000
389	E	A	-1.0636
390	L	A	0.0000
391	C	A	0.0000
392	V	A	0.0000
393	R	A	-1.1201
394	G	A	-0.4485
395	P	A	-0.3090
396	M	A	0.0000
397	I	A	0.0000
398	M	A	0.0000
399	S	A	-0.5221
400	G	A	0.0000
401	Y	A	-0.9059
402	V	A	-0.6057
403	N	A	-1.6509
404	N	A	-1.8135
405	P	A	-1.9331
406	E	A	-2.6071
407	A	A	-1.5424
408	T	A	-1.4700
409	N	A	-2.2766
410	A	A	-1.2456
411	L	A	-0.6544
412	I	A	-1.2410
413	D	A	-2.2926
414	K	A	-3.0483
415	D	A	-2.8969
416	G	A	-1.9938
417	W	A	0.0000
418	L	A	0.0000
419	H	A	-0.7075
420	S	A	-0.4318
421	G	A	-1.0324
422	D	A	-0.6789
423	I	A	0.0206
424	A	A	0.0000
425	Y	A	-0.7313
426	W	A	0.0000
427	D	A	-2.1524
428	E	A	-3.0220
429	D	A	-3.0834
430	E	A	-2.5364
431	H	A	-1.7894
432	F	A	0.0000
433	F	A	0.0984
434	I	A	0.6824
435	V	A	0.8064
441	L	A	1.0458
442	I	A	0.0000
443	K	A	-1.6858
444	Y	A	0.0000
445	K	A	-2.7619
446	G	A	-1.4768
447	Y	A	-0.4519
448	Q	A	-1.1175
449	V	A	0.0000
450	A	A	-0.5370
451	P	A	-0.5156
452	A	A	-0.6712
453	E	A	-1.8122
454	L	A	0.0000
455	E	A	-0.8267
456	S	A	-0.8247
457	I	A	-0.6395
458	L	A	0.0000
459	L	A	0.0686
460	Q	A	-0.8123
461	H	A	-0.4501
462	P	A	-0.4988
463	N	A	-0.7276
464	I	A	0.0000
465	F	A	0.4917
466	D	A	-0.2380
467	A	A	0.0000
468	G	A	0.0000
469	V	A	0.0000
470	A	A	0.0000
471	G	A	0.0000
472	L	A	0.0000
473	P	A	-1.4671
474	D	A	-2.6568
475	D	A	-3.3944
476	D	A	-3.3050
477	A	A	0.0000
478	G	A	-2.8461
479	E	A	-2.3708
480	L	A	-1.8733
481	P	A	0.0000
482	A	A	0.0000
483	A	A	0.0000
484	V	A	0.0000
485	V	A	0.0000
486	V	A	0.0000
487	L	A	-0.3897
488	E	A	-0.8836
489	H	A	-1.3931
490	G	A	-1.4582
491	K	A	-1.3650
492	T	A	-0.7988
493	M	A	0.0000
494	T	A	-1.2622
495	E	A	-1.6064
496	K	A	-2.9552
497	E	A	-2.8236
498	I	A	0.0000
499	V	A	-2.1881
500	D	A	-3.0836
501	Y	A	-1.6487
502	V	A	0.0000
503	A	A	-1.6412
504	S	A	-1.1914
505	Q	A	-1.4952
506	V	A	-0.9183
507	T	A	-0.5852
508	T	A	-0.6513
509	A	A	-1.0561
510	K	A	-1.6466
511	K	A	-1.8280
512	L	A	0.0000
513	R	A	-2.2653
514	G	A	0.0000
515	G	A	0.0000
516	V	A	0.0000
517	V	A	0.4352
518	F	A	0.6922
519	V	A	-0.5261
520	D	A	-2.1327
521	E	A	-2.2543
522	V	A	-1.4462
523	P	A	-1.7411
529	K	A	-1.7871
530	L	A	-1.2237
531	D	A	-2.7243
532	A	A	-2.3506
533	R	A	-3.4358
534	K	A	-3.3188
535	I	A	0.0000
536	R	A	-2.7757
537	E	A	-3.4977
538	I	A	-1.7346
539	L	A	0.0000
540	I	A	-1.5757
541	K	A	-2.2668
542	A	A	-1.1601
543	K	A	-1.5136
544	K	A	-2.2540