Project name: ashraf_ttr [mutate: CA10R]

Status: done

submitted: 2018-04-16 12:48:46, status changed: 2018-04-17 16:51:52
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Chain sequence(s) A: CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN
B: CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN
Distance of aggregation 10 Å
Dynamic mode No
Mutated residues CA10R
Energy difference between WT (input) and mutated protein (by FoldX) -0.0907858 kcal/mol
Show buried residues

Minimal score value
-3.7256
Maximal score value
1.8755
Average score
-0.6992
Total score value
-160.8236

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
10 R A -2.8948 mutated: CA10R
11 P A 0.0000
12 L A 0.0000
13 M A -1.0266
14 V A 0.0000
15 K A -0.7904
16 V A 0.0000
17 L A 0.6048
18 D A 0.0000
19 A A 0.4850
20 V A 0.9112
21 R A -1.0519
22 G A -0.6381
23 S A -0.5155
24 P A -0.6573
25 A A 0.0000
26 I A -0.7313
27 N A -1.8136
28 V A 0.0000
29 A A -1.2636
30 V A 0.0000
31 H A -1.0775
32 V A 0.0000
33 F A -0.7757
34 R A -1.2588
35 K A -1.6284
36 A A -1.7891
37 A A -1.6770
38 D A -2.6582
39 D A -2.9228
40 T A -1.9500
41 W A -1.4150
42 E A -2.1208
43 P A -1.1527
44 F A -0.7244
45 A A -0.4883
46 S A -0.8225
47 G A -1.2992
48 K A -2.1122
49 T A 0.0000
50 S A -1.7425
51 E A -2.1332
52 S A -1.2544
53 G A 0.0000
54 E A -1.3411
55 L A 0.0000
56 H A -1.5038
57 G A -1.2262
58 L A 0.0000
59 T A 0.0000
60 T A -2.4089
61 E A -3.7256
62 E A -3.2400
63 E A -2.8111
64 F A 0.0000
65 V A -1.5457
66 E A -2.1758
67 G A -1.0385
68 I A -0.4109
69 Y A 0.0000
70 K A -0.5256
71 V A 0.0000
72 E A -0.7589
73 I A 0.0000
74 D A -1.3141
75 T A 0.0000
76 K A -1.2687
77 S A -1.1553
78 Y A 0.0000
79 W A 0.0000
80 K A -1.2676
81 A A -0.4131
82 L A 0.1934
83 G A -0.3626
84 I A -0.1304
85 S A -0.3992
86 P A -0.3551
87 F A 0.0000
88 H A 0.0000
89 E A -0.5402
90 H A -0.7171
91 A A 0.0000
92 E A 0.0000
93 V A 0.0000
94 V A 0.0000
95 F A 0.0000
96 T A -0.7350
97 A A 0.0000
98 N A 0.0000
99 D A -2.4778
100 S A -1.5926
101 G A -1.5249
102 P A -2.4536
103 R A -2.9807
104 R A -2.9304
105 Y A 0.0000
106 T A -0.3347
107 I A 0.0000
108 A A 0.1397
109 A A 0.0000
110 L A 0.8360
111 L A 0.0000
112 S A 0.5863
113 P A 0.3556
114 Y A 0.9425
115 S A 0.5374
116 Y A 0.0000
117 S A 0.2235
118 T A 0.0000
119 T A 0.5001
120 A A 0.0000
121 V A 1.5400
122 V A 0.1060
123 T A -1.0038
124 N A -2.0617
10 C B -0.2705
11 P B 0.0000
12 L B 0.0000
13 M B 0.0000
14 V B 0.0000
15 K B -0.4815
16 V B 0.0000
17 L B 0.3996
18 D B 0.0000
19 A B 0.4455
20 V B 0.8394
21 R B -1.0922
22 G B -0.7732
23 S B -0.6283
24 P B -0.7458
25 A B 0.0000
26 I B -1.0641
27 N B -2.0881
28 V B 0.0000
29 A B -1.4695
30 V B 0.0000
31 H B -1.1271
32 V B 0.0000
33 F B -0.8525
34 R B -1.4143
35 K B -1.8681
36 A B -1.9186
37 A B -1.7422
38 D B -2.6949
39 D B -3.0329
40 T B -1.9976
41 W B -1.4738
42 E B -2.1724
43 P B -1.1895
44 F B -0.6668
45 A B -0.4622
46 S B -1.0053
47 G B -1.6144
48 K B -2.6820
49 T B 0.0000
50 S B -1.9491
51 E B -2.2449
52 S B -1.2246
53 G B 0.0000
54 E B -1.4885
55 L B 0.0000
56 H B -1.3854
57 G B -0.7179
58 L B -0.3599
59 T B -1.0638
60 T B -1.7360
61 E B -3.0462
62 E B -3.1107
63 E B -2.5430
64 F B 0.0000
65 V B -1.3900
66 E B -2.0829
67 G B -1.0992
68 I B -0.3720
69 Y B 0.0000
70 K B 0.0000
71 V B 0.0000
72 E B -0.7359
73 I B 0.0000
74 D B -1.3563
75 T B 0.0000
76 K B -1.3744
77 S B -1.3115
78 Y B 0.0000
79 W B 0.0000
80 K B -1.7750
81 A B -0.8356
82 L B -0.1072
83 G B -0.5833
84 I B -0.1901
85 S B -0.3882
86 P B -0.4841
87 F B 0.0000
88 H B 0.0000
89 E B -0.5635
90 H B -0.7358
91 A B 0.0000
92 E B 0.0000
93 V B 0.0000
94 V B 0.0000
95 F B 0.0000
96 T B -0.8102
97 A B 0.0000
98 N B 0.0000
99 D B -2.3831
100 S B -1.5189
101 G B -1.4599
102 P B -2.0424
103 R B -1.8041
104 R B -1.4035
105 Y B 0.0000
106 T B 0.0000
107 I B 0.0000
108 A B 0.3546
109 A B 0.0000
110 L B 1.0529
111 L B 0.0000
112 S B 0.6276
113 P B 0.2763
114 Y B 0.8042
115 S B 0.5116
116 Y B 0.0000
117 S B 0.2740
118 T B 0.0000
119 T B 0.6955
120 A B 0.0000
121 V B 1.8755
122 V B 0.6559
123 T B -0.5436
124 N B -1.7327

 

Laboratory of Theory of Biopolymers 2015