Server for fast simulation of protein structure fluctuations

CABS-flex is an efficient procedure for the simulation of structure flexibility of folded globular proteins. Using an input protein structure the CABS-flex outputs:

a set of protein models (reflecting the flexibility of the input structure, in all-atom PDB format) ready to use in structure-based studies of protein functions and interactions,


residue fluctuation profiles and other accompanying analysis.


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Instead of this web server, we highly recommend to use CABS-flex 2.0 available HERE
CABS-flex 2.0 offers new features that include: extension of the method to significantly larger and multimeric proteins, customizable distance restraints and simulation parameters, contact maps and a new enhanced web server interface (see the paper)

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Our papers describing the CABS-flex server, methodology and its utilization in other modeling pipelines:

© Laboratory of Theory of Biopolymers, Faculty of Chemistry, University of Warsaw 2013