Project name: 11632146a21631e

Chain sequence(s)	A: SNAQVQLVESGGGLVQPGGSLRLSCAASGRTFSSYSMGWFRQAPGKEREFVAAISKGGYKYDAVSLEGRFTISRDNSKNTVYLQMNSLRPEDTAVYYCASSRAYGSSRLRLADTYEYWGQGTLVTVSSAEAAAKEAAAKEAAAKAGC
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:21)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:22)

• Minimal score value: -3.6494
• Maximal score value: 1.7116
• Average score: -0.9149
• Total score value: -134.4874

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	S	A	-0.9650
2	N	A	-1.8389
3	A	A	-1.5666
4	Q	A	-1.8066
5	V	A	-1.2436
6	Q	A	-0.7520
7	L	A	0.0000
8	V	A	1.1538
9	E	A	0.3563
10	S	A	-0.1326
11	G	A	-0.7265
12	G	A	0.0855
13	G	A	0.5942
14	L	A	1.3957
15	V	A	0.2497
16	Q	A	-0.5299
17	P	A	-1.3374
18	G	A	-1.2924
19	G	A	-0.7361
20	S	A	-1.1644
21	L	A	-0.9424
22	R	A	-2.1372
23	L	A	0.0000
24	S	A	-0.4118
25	C	A	0.0000
26	A	A	-0.1546
27	A	A	-0.5713
28	S	A	-0.9328
29	G	A	-1.6469
30	R	A	-2.2295
31	T	A	-1.2264
32	F	A	0.0000
33	S	A	-1.3582
34	S	A	-1.2736
35	Y	A	0.0000
36	S	A	0.0000
37	M	A	0.0000
38	G	A	0.0000
39	W	A	0.0000
40	F	A	0.0000
41	R	A	-1.1487
42	Q	A	-1.9110
43	A	A	-1.7209
44	P	A	-1.3848
45	G	A	-1.9432
46	K	A	-3.4003
47	E	A	-3.6494
48	R	A	-2.9223
49	E	A	-2.5346
50	F	A	0.0000
51	V	A	0.0000
52	A	A	0.0000
53	A	A	0.0000
54	I	A	0.0000
55	S	A	0.0000
56	K	A	-1.5450
57	G	A	-0.7605
58	G	A	-0.5411
59	Y	A	0.1790
60	K	A	-1.1412
61	Y	A	-0.9984
62	D	A	-1.5366
63	A	A	-0.5567
64	V	A	0.7845
65	S	A	-0.1199
66	L	A	0.0000
67	E	A	-1.8179
68	G	A	-1.5275
69	R	A	-1.5799
70	F	A	0.0000
71	T	A	-1.2606
72	I	A	0.0000
73	S	A	-0.5833
74	R	A	-1.2960
75	D	A	-1.8650
76	N	A	-2.2889
77	S	A	-1.8522
78	K	A	-2.5360
79	N	A	-2.2009
80	T	A	0.0000
81	V	A	0.0000
82	Y	A	-0.6516
83	L	A	0.0000
84	Q	A	-1.3040
85	M	A	0.0000
86	N	A	-1.5639
87	S	A	-1.3102
88	L	A	0.0000
89	R	A	-2.6777
90	P	A	-1.9593
91	E	A	-2.4544
92	D	A	0.0000
93	T	A	-0.5363
94	A	A	0.0000
95	V	A	0.6829
96	Y	A	0.0000
97	Y	A	0.0161
98	C	A	0.0000
99	A	A	0.0000
100	S	A	0.0000
101	S	A	0.0000
102	R	A	-2.0038
103	A	A	-1.1375
104	Y	A	0.0694
105	G	A	-0.4485
106	S	A	-0.9571
107	S	A	-1.3916
108	R	A	-2.3010
109	L	A	0.0000
110	R	A	-2.5130
111	L	A	-1.1478
112	A	A	-1.5591
113	D	A	-2.2437
114	T	A	-1.8438
115	Y	A	0.0000
116	E	A	-2.1445
117	Y	A	-0.7736
118	W	A	-0.0724
119	G	A	-0.0518
120	Q	A	-0.8592
121	G	A	0.0616
122	T	A	0.6122
123	L	A	1.7116
124	V	A	0.0000
125	T	A	0.4034
126	V	A	0.0000
127	S	A	-0.4904
128	S	A	-0.5562
129	A	A	-0.5596
130	E	A	-0.7159
131	A	A	-1.2089
132	A	A	-1.1519
133	A	A	-1.5073
134	K	A	-2.9484
135	E	A	-3.2451
136	A	A	-2.3432
137	A	A	-2.1867
138	A	A	-2.5060
139	K	A	-3.3989
140	E	A	-3.3757
141	A	A	-2.0774
142	A	A	-1.5645
143	A	A	-1.7553
144	K	A	-2.2151
145	A	A	-0.9544
146	G	A	-0.5906
147	C	A	0.0135