| Chain sequence(s) |
A: MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITWSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 5 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | RQ533A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 2.46091 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:01)
[INFO] FoldX: Building mutant model (00:02:59)
[INFO] FoldX: Starting FoldX energy minimalization (00:03:40)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:06:49)
[INFO] Main: Simulation completed successfully. (00:06:54)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | 1.0659 | |
| 2 | A | A | 0.0604 | |
| 3 | H | A | -0.5906 | |
| 4 | V | A | 1.2318 | |
| 5 | R | A | -1.6529 | |
| 6 | G | A | -0.6336 | |
| 7 | L | A | 1.1988 | |
| 8 | Q | A | -0.5917 | |
| 9 | L | A | 1.2720 | |
| 10 | P | A | 0.0284 | |
| 11 | G | A | -0.3745 | |
| 12 | C | A | 0.9676 | |
| 13 | L | A | 1.7142 | |
| 14 | A | A | 0.6859 | |
| 15 | L | A | 1.5719 | |
| 16 | A | A | 0.4364 | |
| 17 | A | A | 0.3534 | |
| 18 | L | A | 1.7225 | |
| 19 | C | A | 1.0393 | |
| 20 | S | A | 0.2131 | |
| 21 | L | A | 1.9213 | |
| 22 | V | A | 1.9343 | |
| 23 | H | A | -0.6737 | |
| 24 | S | A | -0.6200 | |
| 25 | Q | A | -1.4180 | |
| 26 | H | A | -0.6573 | |
| 27 | V | A | 1.9367 | |
| 28 | F | A | 2.3368 | |
| 29 | L | A | 1.4435 | |
| 30 | A | A | 0.1734 | |
| 31 | P | A | -0.4194 | |
| 32 | Q | A | -1.4487 | |
| 33 | Q | A | -1.4100 | |
| 34 | A | A | -0.5561 | |
| 35 | R | A | -1.8807 | |
| 36 | S | A | -0.2661 | |
| 37 | L | A | 1.7525 | |
| 38 | L | A | 1.4063 | |
| 39 | Q | A | -1.2905 | |
| 40 | R | A | -1.7401 | |
| 41 | V | A | 1.3429 | |
| 42 | R | A | -0.3977 | |
| 43 | R | A | -1.1808 | |
| 44 | A | A | -0.3360 | |
| 45 | N | A | -0.8297 | |
| 46 | T | A | 0.1588 | |
| 47 | F | A | 2.0882 | |
| 48 | L | A | 1.2161 | |
| 49 | E | A | 0.0000 | |
| 50 | E | A | -1.1335 | |
| 51 | V | A | 1.3066 | |
| 52 | R | A | -1.1728 | |
| 53 | K | A | -1.9277 | |
| 54 | G | A | -0.5542 | |
| 55 | N | A | -0.9443 | |
| 56 | L | A | -0.0198 | |
| 57 | E | A | -0.9170 | |
| 58 | R | A | -0.5567 | |
| 59 | E | A | 0.0000 | |
| 60 | C | A | 0.0000 | |
| 61 | V | A | -0.2192 | |
| 62 | E | A | -1.9824 | |
| 63 | E | A | -1.4556 | |
| 64 | T | A | -0.2721 | |
| 65 | C | A | 0.0000 | |
| 66 | S | A | 0.0455 | |
| 67 | Y | A | 0.1487 | |
| 68 | E | A | -1.5552 | |
| 69 | E | A | 0.0000 | |
| 70 | A | A | 0.0000 | |
| 71 | F | A | 0.6646 | |
| 72 | E | A | -0.1641 | |
| 73 | A | A | 0.0116 | |
| 74 | L | A | 0.0838 | |
| 75 | E | A | -1.7595 | |
| 76 | S | A | -0.4216 | |
| 77 | S | A | -0.2040 | |
| 78 | T | A | -0.0996 | |
| 79 | A | A | 0.0065 | |
| 80 | T | A | 0.0000 | |
| 81 | D | A | -1.4619 | |
| 82 | V | A | 1.4937 | |
| 83 | F | A | 0.5904 | |
| 84 | W | A | 0.2972 | |
| 85 | A | A | 0.0190 | |
| 86 | K | A | -0.2431 | |
| 87 | Y | A | 0.0000 | |
| 88 | T | A | -0.0676 | |
| 89 | A | A | -0.0026 | |
| 90 | C | A | 0.0000 | |
| 91 | E | A | -1.8324 | |
| 92 | T | A | -0.3929 | |
| 93 | A | A | 0.0000 | |
| 94 | R | A | -0.3814 | |
| 95 | T | A | -0.1860 | |
| 96 | P | A | -0.4090 | |
| 97 | R | A | -1.5469 | |
| 98 | D | A | -2.1566 | |
| 99 | K | A | -1.1629 | |
| 100 | L | A | 0.0000 | |
| 101 | A | A | 0.0192 | |
| 102 | A | A | 0.0188 | |
| 103 | C | A | 0.0000 | |
| 104 | L | A | -0.1563 | |
| 105 | E | A | -1.7889 | |
| 106 | G | A | 0.0000 | |
| 107 | N | A | -1.2601 | |
| 108 | C | A | -0.1548 | |
| 109 | A | A | 0.0000 | |
| 110 | E | A | -0.3449 | |
| 111 | G | A | -0.4110 | |
| 112 | L | A | 0.4852 | |
| 113 | G | A | 0.0000 | |
| 114 | T | A | -0.0222 | |
| 115 | N | A | 0.0000 | |
| 116 | Y | A | 0.0000 | |
| 117 | R | A | -0.2627 | |
| 118 | G | A | 0.0000 | |
| 119 | H | A | -0.8992 | |
| 120 | V | A | 0.2533 | |
| 121 | N | A | -0.1943 | |
| 122 | I | A | 0.5602 | |
| 123 | T | A | 0.0000 | |
| 124 | W | A | 0.3497 | |
| 125 | S | A | -0.0906 | |
| 126 | G | A | -0.3531 | |
| 127 | I | A | -0.0309 | |
| 128 | E | A | -0.7392 | |
| 129 | C | A | 0.0000 | |
| 130 | Q | A | 0.0000 | |
| 131 | L | A | 0.3327 | |
| 132 | W | A | 0.0000 | |
| 133 | R | A | -1.3007 | |
| 134 | S | A | 0.0000 | |
| 135 | R | A | -0.5624 | |
| 136 | Y | A | 0.0642 | |
| 137 | P | A | 0.0000 | |
| 138 | H | A | 0.0000 | |
| 139 | K | A | -1.0105 | |
| 140 | P | A | -0.5033 | |
| 141 | E | A | -1.6710 | |
| 142 | I | A | 0.0000 | |
| 143 | N | A | -0.4375 | |
| 144 | S | A | -0.1679 | |
| 145 | T | A | -0.0898 | |
| 146 | T | A | -0.1204 | |
| 147 | H | A | -0.3462 | |
| 148 | P | A | -0.3926 | |
| 149 | G | A | -0.4963 | |
| 150 | A | A | -0.1779 | |
| 151 | D | A | -0.5766 | |
| 152 | L | A | 0.0000 | |
| 153 | Q | A | -0.9887 | |
| 154 | E | A | -1.9613 | |
| 155 | N | A | -0.3517 | |
| 156 | F | A | 0.1354 | |
| 157 | C | A | 0.0000 | |
| 158 | R | A | 0.0000 | |
| 159 | N | A | 0.0000 | |
| 160 | P | A | -0.1530 | |
| 161 | D | A | -0.7089 | |
| 162 | S | A | -0.3368 | |
| 163 | S | A | -0.0865 | |
| 164 | T | A | -0.0900 | |
| 165 | T | A | -0.0836 | |
| 166 | G | A | 0.0000 | |
| 167 | P | A | 0.0000 | |
| 168 | W | A | 0.0000 | |
| 169 | C | A | 0.0000 | |
| 170 | Y | A | 0.0000 | |
| 171 | T | A | 0.0000 | |
| 172 | T | A | -0.0739 | |
| 173 | D | A | -0.2059 | |
| 174 | P | A | -0.0721 | |
| 175 | T | A | -0.0127 | |
| 176 | V | A | 0.2006 | |
| 177 | R | A | -0.7811 | |
| 178 | R | A | -0.6782 | |
| 179 | Q | A | -0.4044 | |
| 180 | E | A | -0.2446 | |
| 181 | C | A | 0.0000 | |
| 182 | S | A | -0.0366 | |
| 183 | I | A | 0.0000 | |
| 184 | P | A | 0.0798 | |
| 185 | V | A | 0.2225 | |
| 186 | C | A | 0.0000 | |
| 187 | G | A | -0.6795 | |
| 188 | Q | A | -1.6036 | |
| 189 | D | A | -2.2230 | |
| 190 | Q | A | -1.2919 | |
| 191 | V | A | 1.0282 | |
| 192 | T | A | 0.2612 | |
| 193 | V | A | 0.3189 | |
| 194 | A | A | 0.2104 | |
| 195 | M | A | 0.5588 | |
| 196 | T | A | -0.0254 | |
| 197 | P | A | -0.6095 | |
| 198 | R | A | -1.9300 | |
| 199 | S | A | -0.8971 | |
| 200 | E | A | -1.9464 | |
| 201 | G | A | -0.8432 | |
| 202 | S | A | -0.3396 | |
| 203 | S | A | 0.0655 | |
| 204 | V | A | 1.5103 | |
| 205 | N | A | -0.6851 | |
| 206 | L | A | 1.2831 | |
| 207 | S | A | 0.0014 | |
| 208 | P | A | -0.3569 | |
| 209 | P | A | -0.0214 | |
| 210 | L | A | 1.1793 | |
| 211 | E | A | -1.7570 | |
| 212 | Q | A | -1.4184 | |
| 213 | C | A | 0.3912 | |
| 214 | V | A | 0.3719 | |
| 215 | P | A | -0.2669 | |
| 216 | D | A | -1.2220 | |
| 217 | R | A | 0.0000 | |
| 218 | G | A | 0.0000 | |
| 219 | Q | A | -0.8225 | |
| 220 | Q | A | -1.2747 | |
| 221 | Y | A | -0.2512 | |
| 222 | Q | A | -1.1883 | |
| 223 | G | A | -0.6723 | |
| 224 | R | A | -1.7891 | |
| 225 | L | A | 0.0992 | |
| 226 | A | A | 0.2507 | |
| 227 | V | A | 0.8858 | |
| 228 | T | A | 0.0000 | |
| 229 | T | A | -0.1967 | |
| 230 | H | A | -1.0769 | |
| 231 | G | A | -0.5408 | |
| 232 | L | A | 0.4431 | |
| 233 | P | A | -0.0427 | |
| 234 | C | A | 0.0000 | |
| 235 | L | A | 0.3130 | |
| 236 | A | A | 0.0300 | |
| 237 | W | A | 0.0000 | |
| 238 | A | A | 0.0466 | |
| 239 | S | A | -0.0456 | |
| 240 | A | A | -0.0635 | |
| 241 | Q | A | -0.6014 | |
| 242 | A | A | 0.0000 | |
| 243 | K | A | -1.6824 | |
| 244 | A | A | -0.1840 | |
| 245 | L | A | 0.4114 | |
| 246 | S | A | -0.2676 | |
| 247 | K | A | -1.8849 | |
| 248 | H | A | -1.3733 | |
| 249 | Q | A | -0.9339 | |
| 250 | D | A | -1.8010 | |
| 251 | F | A | -0.2151 | |
| 252 | N | A | -1.2445 | |
| 253 | S | A | -0.4324 | |
| 254 | A | A | 0.0527 | |
| 255 | V | A | -0.0269 | |
| 256 | Q | A | -1.0708 | |
| 257 | L | A | 0.3891 | |
| 258 | V | A | 0.2157 | |
| 259 | E | A | -1.7952 | |
| 260 | N | A | -0.6326 | |
| 261 | F | A | 0.0000 | |
| 262 | C | A | 0.0000 | |
| 263 | R | A | 0.0000 | |
| 264 | N | A | 0.0000 | |
| 265 | P | A | 0.0000 | |
| 266 | D | A | -0.1961 | |
| 267 | G | A | -0.3102 | |
| 268 | D | A | 0.0000 | |
| 269 | E | A | -0.2985 | |
| 270 | E | A | 0.0000 | |
| 271 | G | A | 0.0000 | |
| 272 | V | A | 0.0000 | |
| 273 | W | A | 0.0000 | |
| 274 | C | A | 0.0000 | |
| 275 | Y | A | 0.0000 | |
| 276 | V | A | 0.0000 | |
| 277 | A | A | -0.0261 | |
| 278 | G | A | -0.7687 | |
| 279 | K | A | -1.8039 | |
| 280 | P | A | -0.4168 | |
| 281 | G | A | -0.1648 | |
| 282 | D | A | -0.5019 | |
| 283 | F | A | 0.1164 | |
| 284 | G | A | 0.0000 | |
| 285 | Y | A | 0.0000 | |
| 286 | C | A | 0.0000 | |
| 287 | D | A | -1.7456 | |
| 288 | L | A | -0.3142 | |
| 289 | N | A | -1.1974 | |
| 290 | Y | A | 0.0005 | |
| 291 | C | A | -0.1289 | |
| 292 | E | A | -1.8582 | |
| 293 | E | A | -0.6513 | |
| 294 | A | A | -0.0522 | |
| 295 | V | A | 0.0000 | |
| 296 | E | A | -0.6727 | |
| 297 | E | A | -1.9857 | |
| 298 | E | A | -0.9163 | |
| 299 | T | A | -0.2625 | |
| 300 | G | A | -0.7977 | |
| 301 | D | A | -1.9548 | |
| 302 | G | A | -0.5073 | |
| 303 | L | A | 1.1355 | |
| 304 | D | A | -1.8327 | |
| 305 | E | A | -2.4860 | |
| 306 | D | A | -2.1767 | |
| 307 | S | A | -0.8527 | |
| 308 | D | A | -2.1581 | |
| 309 | R | A | -2.1540 | |
| 310 | A | A | 0.0806 | |
| 311 | I | A | 1.6904 | |
| 312 | E | A | -1.5378 | |
| 313 | G | A | -1.1540 | |
| 314 | R | A | -1.9459 | |
| 315 | T | A | -0.3946 | |
| 316 | A | A | 0.0230 | |
| 317 | T | A | -0.1010 | |
| 318 | S | A | -0.5613 | |
| 319 | E | A | -1.8165 | |
| 320 | Y | A | -0.3141 | |
| 321 | Q | A | -1.1614 | |
| 322 | T | A | -0.1047 | |
| 323 | F | A | 0.7866 | |
| 324 | F | A | 0.0000 | |
| 325 | N | A | -0.9958 | |
| 326 | P | A | -0.7501 | |
| 327 | R | A | -1.8907 | |
| 328 | T | A | -0.3378 | |
| 329 | F | A | 0.0000 | |
| 330 | G | A | 0.0000 | |
| 331 | S | A | -0.1734 | |
| 332 | G | A | -0.0859 | |
| 333 | E | A | 0.0000 | |
| 334 | A | A | -0.0678 | |
| 335 | D | A | -0.6974 | |
| 336 | C | A | 0.0000 | |
| 337 | G | A | 0.0000 | |
| 338 | L | A | 0.2788 | |
| 339 | R | A | 0.0000 | |
| 340 | P | A | 0.0000 | |
| 341 | L | A | 0.2891 | |
| 342 | F | A | 0.0000 | |
| 343 | E | A | -0.4824 | |
| 344 | K | A | -1.6141 | |
| 345 | K | A | -1.9644 | |
| 346 | S | A | -0.3246 | |
| 347 | L | A | 0.8424 | |
| 348 | E | A | -1.5997 | |
| 349 | D | A | 0.0000 | |
| 350 | K | A | -0.4588 | |
| 351 | T | A | -0.1338 | |
| 352 | E | A | -0.5744 | |
| 353 | R | A | -1.9329 | |
| 354 | E | A | -0.5847 | |
| 355 | L | A | 0.0000 | |
| 356 | L | A | 0.4725 | |
| 357 | E | A | -1.2297 | |
| 358 | S | A | -0.3751 | |
| 359 | Y | A | 0.4796 | |
| 360 | I | A | 0.3937 | |
| 361 | D | A | -1.7064 | |
| 362 | G | A | -0.8222 | |
| 363 | R | A | -1.7110 | |
| 364 | I | A | 0.6096 | |
| 365 | V | A | 0.0973 | |
| 366 | E | A | -1.8020 | |
| 367 | G | A | -0.5179 | |
| 368 | S | A | -0.4455 | |
| 369 | D | A | -1.8236 | |
| 370 | A | A | 0.0000 | |
| 371 | E | A | -0.5148 | |
| 372 | I | A | 1.0643 | |
| 373 | G | A | 0.1983 | |
| 374 | M | A | 0.0000 | |
| 375 | S | A | 0.0000 | |
| 376 | P | A | 0.0000 | |
| 377 | W | A | 0.0000 | |
| 378 | Q | A | 0.0000 | |
| 379 | V | A | 0.0000 | |
| 380 | M | A | 0.0000 | |
| 381 | L | A | 0.0000 | |
| 382 | F | A | 0.0855 | |
| 383 | R | A | -0.7926 | |
| 384 | K | A | -0.7880 | |
| 385 | S | A | -0.4968 | |
| 386 | P | A | -0.5328 | |
| 387 | Q | A | -1.6365 | |
| 388 | E | A | -1.9291 | |
| 389 | L | A | -0.0258 | |
| 390 | L | A | 0.2129 | |
| 391 | C | A | 0.0000 | |
| 392 | G | A | 0.0000 | |
| 393 | A | A | 0.0000 | |
| 394 | S | A | 0.0000 | |
| 395 | L | A | 0.0000 | |
| 396 | I | A | 0.0000 | |
| 397 | S | A | 0.0000 | |
| 398 | D | A | 0.0000 | |
| 399 | R | A | -0.3532 | |
| 400 | W | A | 0.0000 | |
| 401 | V | A | 0.0000 | |
| 402 | L | A | 0.0000 | |
| 403 | T | A | 0.0000 | |
| 404 | A | A | 0.0000 | |
| 405 | A | A | 0.0000 | |
| 406 | H | A | 0.0000 | |
| 407 | C | A | 0.0000 | |
| 408 | L | A | 0.0000 | |
| 409 | L | A | 0.2114 | |
| 410 | Y | A | 0.0000 | |
| 411 | P | A | -0.3312 | |
| 412 | P | A | -0.0216 | |
| 413 | W | A | -0.1867 | |
| 414 | D | A | -1.8135 | |
| 415 | K | A | -0.7478 | |
| 416 | N | A | -1.2121 | |
| 417 | F | A | 0.0310 | |
| 418 | T | A | -0.0478 | |
| 419 | E | A | -0.4837 | |
| 420 | N | A | -1.4553 | |
| 421 | D | A | -0.9981 | |
| 422 | L | A | 0.0000 | |
| 423 | L | A | 0.2288 | |
| 424 | V | A | 0.0000 | |
| 425 | R | A | 0.0000 | |
| 426 | I | A | 0.0000 | |
| 427 | G | A | 0.0000 | |
| 428 | K | A | 0.0000 | |
| 429 | H | A | -0.1596 | |
| 430 | S | A | -0.0697 | |
| 431 | R | A | -0.3900 | |
| 432 | T | A | -0.4698 | |
| 433 | R | A | -1.7302 | |
| 434 | Y | A | 0.3399 | |
| 435 | E | A | 0.0000 | |
| 436 | R | A | -2.0717 | |
| 437 | N | A | -1.5591 | |
| 438 | I | A | -0.0153 | |
| 439 | E | A | -0.2915 | |
| 440 | K | A | -0.8488 | |
| 441 | I | A | 0.2182 | |
| 442 | S | A | 0.0000 | |
| 443 | M | A | 0.4425 | |
| 444 | L | A | 0.0000 | |
| 445 | E | A | -0.9768 | |
| 446 | K | A | -0.9943 | |
| 447 | I | A | 0.0701 | |
| 448 | Y | A | 0.2802 | |
| 449 | I | A | 0.4519 | |
| 450 | H | A | 0.0000 | |
| 451 | P | A | -0.0371 | |
| 452 | R | A | 0.0000 | |
| 453 | Y | A | 0.0000 | |
| 454 | N | A | -0.1930 | |
| 455 | W | A | 0.0023 | |
| 456 | R | A | -1.6000 | |
| 457 | E | A | -2.0825 | |
| 458 | N | A | -0.4597 | |
| 459 | L | A | 0.0000 | |
| 460 | D | A | -0.2396 | |
| 461 | R | A | -0.2251 | |
| 462 | D | A | 0.0000 | |
| 463 | I | A | 0.0000 | |
| 464 | A | A | 0.0000 | |
| 465 | L | A | 0.0000 | |
| 466 | M | A | 0.0000 | |
| 467 | K | A | 0.0000 | |
| 468 | L | A | 0.0000 | |
| 469 | K | A | -1.5408 | |
| 470 | K | A | -1.9357 | |
| 471 | P | A | -0.4986 | |
| 472 | V | A | 0.0000 | |
| 473 | A | A | 0.1724 | |
| 474 | F | A | 0.6176 | |
| 475 | S | A | -0.2204 | |
| 476 | D | A | -1.2060 | |
| 477 | Y | A | 0.0886 | |
| 478 | I | A | 0.0000 | |
| 479 | H | A | 0.0000 | |
| 480 | P | A | 0.0000 | |
| 481 | V | A | 0.0000 | |
| 482 | C | A | 0.0000 | |
| 483 | L | A | 0.0000 | |
| 484 | P | A | 0.0000 | |
| 485 | D | A | -1.1848 | |
| 486 | R | A | -0.7946 | |
| 487 | E | A | -1.8695 | |
| 488 | T | A | -0.3407 | |
| 489 | A | A | 0.0000 | |
| 490 | A | A | -0.0091 | |
| 491 | S | A | -0.0806 | |
| 492 | L | A | 0.0000 | |
| 493 | L | A | -0.0311 | |
| 494 | Q | A | -1.0808 | |
| 495 | A | A | -0.2262 | |
| 496 | G | A | -0.1789 | |
| 497 | Y | A | 0.4284 | |
| 498 | K | A | 0.0000 | |
| 499 | G | A | 0.0000 | |
| 500 | R | A | 0.0000 | |
| 501 | V | A | 0.0000 | |
| 502 | T | A | 0.0000 | |
| 503 | G | A | 0.0000 | |
| 504 | W | A | 0.0000 | |
| 505 | G | A | -0.0476 | |
| 506 | N | A | 0.0000 | |
| 507 | L | A | 0.0000 | |
| 508 | K | A | -0.4925 | |
| 509 | E | A | -0.8795 | |
| 510 | T | A | -0.1582 | |
| 511 | W | A | 0.0000 | |
| 512 | T | A | 0.0000 | |
| 513 | A | A | -0.0178 | |
| 514 | N | A | -0.0099 | |
| 515 | V | A | 1.6288 | |
| 516 | G | A | -0.4458 | |
| 517 | K | A | -1.8673 | |
| 518 | G | A | -0.8078 | |
| 519 | Q | A | -0.2700 | |
| 520 | P | A | -0.1196 | |
| 521 | S | A | -0.0810 | |
| 522 | V | A | 0.4047 | |
| 523 | L | A | 0.0000 | |
| 524 | Q | A | -0.3633 | |
| 525 | V | A | 0.0000 | |
| 526 | V | A | 0.0000 | |
| 527 | N | A | 0.0000 | |
| 528 | L | A | 0.0000 | |
| 529 | P | A | 0.0368 | |
| 530 | I | A | 0.3517 | |
| 531 | V | A | 0.0000 | |
| 532 | E | A | -1.8461 | |
| 533 | Q | A | -0.5164 | mutated: RQ533A |
| 534 | P | A | -0.1698 | |
| 535 | V | A | 0.4812 | |
| 536 | C | A | 0.0000 | |
| 537 | K | A | -1.3205 | |
| 538 | D | A | -1.9754 | |
| 539 | S | A | -0.3599 | |
| 540 | T | A | 0.0000 | |
| 541 | R | A | -1.7223 | |
| 542 | I | A | 0.0112 | |
| 543 | R | A | -1.6825 | |
| 544 | I | A | -0.1232 | |
| 545 | T | A | -0.0112 | |
| 546 | D | A | -0.2188 | |
| 547 | N | A | 0.0000 | |
| 548 | M | A | 0.0000 | |
| 549 | F | A | 0.0000 | |
| 550 | C | A | 0.0000 | |
| 551 | A | A | 0.0000 | |
| 552 | G | A | 0.0000 | |
| 553 | Y | A | 0.0000 | |
| 554 | K | A | -1.7080 | |
| 555 | P | A | -0.6694 | |
| 556 | D | A | -2.0446 | |
| 557 | E | A | -2.2125 | |
| 558 | G | A | -1.0417 | |
| 559 | K | A | -1.7352 | |
| 560 | R | A | -1.9061 | |
| 561 | G | A | -0.4818 | |
| 562 | D | A | -0.3468 | |
| 563 | A | A | 0.0000 | |
| 564 | C | A | 0.0000 | |
| 565 | E | A | -0.4896 | |
| 566 | G | A | 0.0000 | |
| 567 | D | A | 0.0000 | |
| 568 | S | A | 0.0000 | |
| 569 | G | A | 0.0000 | |
| 570 | G | A | 0.0000 | |
| 571 | P | A | 0.0000 | |
| 572 | F | A | 0.0000 | |
| 573 | V | A | 0.0000 | |
| 574 | M | A | 0.0000 | |
| 575 | K | A | -0.1967 | |
| 576 | S | A | 0.0000 | |
| 577 | P | A | 0.1400 | |
| 578 | F | A | 1.7338 | |
| 579 | N | A | -0.1666 | |
| 580 | N | A | -1.3549 | |
| 581 | R | A | -0.4203 | |
| 582 | W | A | 0.0000 | |
| 583 | Y | A | 0.0000 | |
| 584 | Q | A | 0.0000 | |
| 585 | M | A | 0.0000 | |
| 586 | G | A | 0.0000 | |
| 587 | I | A | 0.0000 | |
| 588 | V | A | 0.0000 | |
| 589 | S | A | 0.0000 | |
| 590 | W | A | 0.0000 | |
| 591 | G | A | 0.0000 | |
| 592 | E | A | 0.0000 | |
| 593 | G | A | 0.0000 | |
| 594 | C | A | 0.0000 | |
| 595 | D | A | -0.5461 | |
| 596 | R | A | -1.9393 | |
| 597 | D | A | -2.2914 | |
| 598 | G | A | -0.6027 | |
| 599 | K | A | -0.2982 | |
| 600 | Y | A | 0.0000 | |
| 601 | G | A | 0.0000 | |
| 602 | F | A | 0.0000 | |
| 603 | Y | A | 0.0000 | |
| 604 | T | A | 0.0000 | |
| 605 | H | A | 0.0000 | |
| 606 | V | A | 0.0000 | |
| 607 | F | A | 0.0000 | |
| 608 | R | A | 0.0000 | |
| 609 | L | A | 0.0000 | |
| 610 | K | A | -0.2273 | |
| 611 | K | A | -0.3937 | |
| 612 | W | A | 0.0000 | |
| 613 | I | A | 0.0000 | |
| 614 | Q | A | -0.2319 | |
| 615 | K | A | -0.1978 | |
| 616 | V | A | 0.0000 | |
| 617 | I | A | 0.0000 | |
| 618 | D | A | -0.6393 | |
| 619 | Q | A | -0.1730 | |
| 620 | F | A | 1.1371 | |
| 621 | G | A | -0.2837 | |
| 622 | E | A | -1.8399 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine