Project name: 7VEN

Chain sequence(s)	H: QVQLVQSGAEVKKPGASVKVSCKASGYTFTNHYMHWVRQAPGQGLEWMGIINPISGSTSNAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARDIVDAFDFWGQGTMVTVSS; L: AIQLTQSPSSLSASVGDRVTITCRASQGISSALVWYQQKPGKAPKLLIYDASSLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQFNDYFTFGPGTKVDIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:05)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:06)

• Minimal score value: -2.8248
• Maximal score value: 1.5541
• Average score: -0.5192
• Total score value: -115.7821

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5036
2	V	H	-0.8149
3	Q	H	-1.1937
4	L	H	0.0000
5	V	H	0.4696
6	Q	H	0.0000
7	S	H	-0.4778
8	G	H	-0.4957
9	A	H	0.1225
11	E	H	0.0944
12	V	H	1.0257
13	K	H	-0.8361
14	K	H	-2.0819
15	P	H	-2.0670
16	G	H	-1.4556
17	A	H	-1.1452
18	S	H	-1.3256
19	V	H	0.0000
20	K	H	-1.8796
21	V	H	0.0000
22	S	H	-0.5806
23	C	H	0.0000
24	K	H	-0.8945
25	A	H	0.0000
26	S	H	-0.8302
27	G	H	-1.0176
28	Y	H	-0.6199
29	T	H	-0.4678
30	F	H	0.0000
35	T	H	0.1190
36	N	H	-0.7208
37	H	H	0.2144
38	Y	H	0.9726
39	M	H	0.0000
40	H	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	0.0000
44	Q	H	-0.5600
45	A	H	-0.9663
46	P	H	-0.8444
47	G	H	-1.2469
48	Q	H	-1.7054
49	G	H	-1.0867
50	L	H	0.0000
51	E	H	-0.7870
52	W	H	0.0000
53	M	H	0.0000
54	G	H	0.0000
55	I	H	0.2538
56	I	H	0.0000
57	N	H	0.3749
58	P	H	0.0000
59	I	H	1.5541
62	S	H	0.5358
63	G	H	0.1286
64	S	H	-0.0378
65	T	H	-0.2200
66	S	H	-0.4670
67	N	H	-1.1613
68	A	H	0.0000
69	Q	H	-2.4266
70	K	H	-2.8006
71	F	H	0.0000
72	Q	H	-2.5447
74	G	H	-1.7057
75	R	H	-1.5324
76	V	H	0.0000
77	T	H	-0.9616
78	M	H	0.0000
79	T	H	-0.5337
80	R	H	-0.7008
81	D	H	-0.9524
82	T	H	-0.2469
83	S	H	-0.4905
84	T	H	-0.6159
85	S	H	-0.7089
86	T	H	0.0000
87	V	H	0.0000
88	Y	H	-0.7184
89	M	H	0.0000
90	E	H	-1.5674
91	L	H	0.0000
92	S	H	-1.1334
93	S	H	-1.1490
94	L	H	0.0000
95	R	H	-2.7004
96	S	H	-2.1758
97	E	H	-2.4232
98	D	H	0.0000
99	T	H	-0.7415
100	A	H	0.0000
101	V	H	0.2614
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	R	H	0.0000
107	D	H	0.5118
108	I	H	1.1254
109	V	H	1.1655
113	D	H	-0.9783
114	A	H	0.0000
115	F	H	0.0000
116	D	H	0.0000
117	F	H	0.6734
118	W	H	-0.0028
119	G	H	0.0000
120	Q	H	-1.2275
121	G	H	-0.6084
122	T	H	0.0000
123	M	H	0.3637
124	V	H	0.0000
125	T	H	-0.1512
126	V	H	0.0000
127	S	H	-1.1419
128	S	H	-1.1694
1	A	L	-0.5045
2	I	L	0.0000
3	Q	L	-1.8486
4	L	L	0.0000
5	T	L	-1.2881
6	Q	L	0.0000
7	S	L	-0.6111
8	P	L	-0.5526
9	S	L	-0.8287
10	S	L	-1.0366
11	L	L	-0.4856
12	S	L	-0.5596
13	A	L	0.0000
14	S	L	0.0722
15	V	L	0.8886
16	G	L	-0.3580
17	D	L	-1.3570
18	R	L	-2.0457
19	V	L	0.0000
20	T	L	-0.5659
21	I	L	0.0000
22	T	L	-0.8267
23	C	L	0.0000
24	R	L	-2.8248
25	A	L	0.0000
26	S	L	-1.8294
27	Q	L	-2.2496
28	G	L	-1.6836
29	I	L	0.0000
36	S	L	-1.1658
37	S	L	-1.2336
38	A	L	-1.3113
39	L	L	0.0000
40	V	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	-0.9150
44	Q	L	0.0000
45	K	L	-1.8457
46	P	L	-1.3207
47	G	L	-1.6638
48	K	L	-2.5414
49	A	L	-1.4267
50	P	L	0.0000
51	K	L	-1.0230
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	-0.3687
56	D	L	-1.7439
57	A	L	0.0000
65	S	L	-0.7458
66	S	L	-0.3952
67	L	L	0.1464
68	E	L	-0.1481
69	S	L	-0.3875
70	G	L	-0.5087
71	V	L	-0.3084
72	P	L	-0.3394
74	S	L	-0.4034
75	R	L	-0.7402
76	F	L	0.0000
77	S	L	-0.3004
78	G	L	-0.4518
79	S	L	-0.8581
80	G	L	-1.2394
83	S	L	-1.2737
84	G	L	-1.2967
85	T	L	-1.8384
86	D	L	-2.2131
87	F	L	0.0000
88	T	L	-0.7452
89	L	L	0.0000
90	T	L	-0.5899
91	I	L	0.0000
92	S	L	-1.1659
93	S	L	-0.9323
94	L	L	0.0000
95	Q	L	-0.5733
96	P	L	-0.4663
97	E	L	-1.5468
98	D	L	0.0000
99	F	L	-0.3455
100	A	L	0.0000
101	T	L	-1.1231
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	Q	L	0.0000
107	F	L	0.0000
108	N	L	-1.5370
114	D	L	-0.7489
115	Y	L	0.6617
116	F	L	0.2981
117	T	L	-0.1639
118	F	L	0.0000
119	G	L	0.0000
120	P	L	-0.9295
121	G	L	0.0000
122	T	L	0.0000
123	K	L	-2.0097
124	V	L	0.0000
125	D	L	-0.4025
126	I	L	1.2111
127	K	L	-0.6828