Project name: 1666e811b2822e1

Chain sequence(s)	C: EVQLVESGGGLVQPGGSLRLSCAASGSARGANAAWFRQAPGKGRELVARAGPLGPVVPPGLAGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAVDPSGELPALPLTGWGQGTQVTVSS
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:52)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:52)

• Minimal score value: -3.0167
• Maximal score value: 1.5992
• Average score: -0.6865
• Total score value: -82.382

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	C	-1.9332
2	V	C	-1.0880
3	Q	C	-0.8093
4	L	C	0.0000
5	V	C	1.3641
6	E	C	0.0000
7	S	C	-0.5287
8	G	C	-0.9764
9	G	C	-0.7588
10	G	C	0.1286
11	L	C	0.9991
12	V	C	0.0226
13	Q	C	-1.2851
14	P	C	-1.4701
15	G	C	-1.3609
16	G	C	-0.8877
17	S	C	-1.0808
18	L	C	-0.8769
19	R	C	-2.0787
20	L	C	0.0000
21	S	C	-0.5194
22	C	C	0.0000
23	A	C	-0.1286
24	A	C	0.0000
25	S	C	-1.0867
26	G	C	-1.3628
27	S	C	-1.3575
28	A	C	0.0000
29	R	C	-2.1257
30	G	C	0.0000
31	A	C	-2.1189
32	N	C	-1.6025
33	A	C	0.0000
34	A	C	0.0000
35	W	C	0.0000
36	F	C	-0.4595
37	R	C	0.0000
38	Q	C	-1.8699
39	A	C	-1.8188
40	P	C	-1.2405
41	G	C	-1.7271
42	K	C	-2.8491
43	G	C	-2.5812
44	R	C	-2.7269
45	E	C	-2.2891
46	L	C	-0.5752
47	V	C	0.0000
48	A	C	0.0000
49	R	C	-0.7621
50	A	C	-0.6459
51	G	C	-0.0244
52	P	C	0.3498
53	L	C	1.3544
54	G	C	0.4119
55	P	C	0.0419
56	V	C	0.6331
57	V	C	0.2193
58	P	C	-0.2563
59	P	C	-0.4186
60	G	C	-0.6567
61	L	C	0.0000
62	A	C	-0.3335
63	G	C	-0.7519
64	R	C	-0.9818
65	F	C	0.0000
66	T	C	-0.6292
67	I	C	0.0000
68	S	C	-1.4294
69	R	C	-2.7868
70	D	C	-2.5908
71	N	C	-3.0167
72	A	C	-1.9640
73	K	C	-2.7990
74	R	C	-2.8383
75	M	C	-1.8436
76	V	C	0.0000
77	Y	C	-1.0330
78	L	C	0.0000
79	Q	C	-1.2533
80	M	C	0.0000
81	N	C	-1.3791
82	S	C	-1.2225
83	L	C	0.0000
84	R	C	-2.2263
85	A	C	-1.7153
86	E	C	-2.2129
87	D	C	0.0000
88	T	C	-0.8251
89	A	C	0.0000
90	V	C	-0.4181
91	Y	C	0.0000
92	Y	C	0.0324
93	C	C	0.0000
94	A	C	0.0000
95	A	C	0.0000
96	V	C	-0.2096
97	D	C	-0.8444
98	P	C	-1.0825
99	S	C	-1.1040
100	G	C	-1.2692
101	E	C	-1.9862
102	L	C	-0.2939
103	P	C	-0.0499
104	A	C	0.5868
105	L	C	1.5992
106	P	C	0.3910
107	L	C	0.6204
108	T	C	0.0960
109	G	C	-0.2218
110	W	C	0.4279
111	G	C	0.1178
112	Q	C	-0.8058
113	G	C	0.0000
114	T	C	-0.6272
115	Q	C	-1.0758
116	V	C	0.0000
117	T	C	-0.2919
118	V	C	0.0000
119	S	C	-0.7628
120	S	C	-0.5647