Project name: 173c4f86ece6afc

Chain sequence(s)	G: IQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQSSYSLITFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGE
Selected Chain(s)	G
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with G chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:55)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:56)

• Minimal score value: -3.5952
• Maximal score value: 3.2695
• Average score: -0.6707
• Total score value: -140.838

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	I	G	0.7671
3	Q	G	-1.3045
4	M	G	0.0000
5	T	G	-1.2182
6	Q	G	0.0000
7	S	G	-0.8426
8	P	G	-0.6678
9	S	G	-0.9162
10	S	G	-0.9059
11	L	G	-0.7395
12	S	G	-1.2868
13	A	G	-1.1831
14	S	G	-1.0324
15	V	G	0.0433
16	G	G	-0.6129
17	D	G	-1.8047
18	R	G	-2.3027
19	V	G	0.0000
20	T	G	-0.6451
21	I	G	0.0000
22	T	G	-0.8221
23	C	G	0.0000
24	R	G	-2.6732
25	A	G	0.0000
26	S	G	-1.4720
27	Q	G	-1.7089
28	S	G	-1.1265
29	V	G	0.0000
36	S	G	-0.3669
37	S	G	-0.4375
38	A	G	0.3176
39	V	G	0.0000
40	A	G	0.7209
41	W	G	0.0000
42	Y	G	-0.0991
43	Q	G	0.0000
44	Q	G	-1.4788
45	K	G	-1.9413
46	P	G	-1.5373
47	G	G	-1.5572
48	K	G	-2.4139
49	A	G	-1.4565
50	P	G	-1.4118
51	K	G	-1.5789
52	L	G	0.0422
53	L	G	0.0000
54	I	G	0.0000
55	Y	G	1.1957
56	S	G	0.1560
57	A	G	0.0000
65	S	G	-0.1167
66	S	G	0.4689
67	L	G	1.0123
68	Y	G	1.1597
69	S	G	0.2643
70	G	G	-0.1486
71	V	G	0.0544
72	P	G	-0.1504
74	S	G	-0.3575
75	R	G	-0.7247
76	F	G	0.0000
77	S	G	-0.2481
78	G	G	-0.3089
79	S	G	-0.9369
80	R	G	-1.6868
83	S	G	-1.2982
84	G	G	-1.4137
85	T	G	-1.6502
86	D	G	-1.7412
87	F	G	0.0000
88	T	G	-0.8405
89	L	G	0.0000
90	T	G	-0.6023
91	I	G	0.0000
92	S	G	-1.3088
93	S	G	-0.9537
94	L	G	0.0000
95	Q	G	-1.0073
96	P	G	-1.6712
97	E	G	-1.9792
98	D	G	0.0000
99	F	G	-1.2329
100	A	G	0.0000
101	T	G	-0.8334
102	Y	G	0.0000
103	Y	G	-0.0682
104	C	G	0.0000
105	Q	G	0.0000
106	Q	G	0.0000
107	S	G	1.5426
108	S	G	1.4821
109	Y	G	2.1786
114	S	G	1.6874
115	L	G	3.1169
116	I	G	3.2695
117	T	G	1.8376
118	F	G	1.4279
119	G	G	-0.4774
120	Q	G	-1.1492
121	G	G	-0.7840
122	T	G	0.0000
123	K	G	-1.5275
124	V	G	0.0000
125	E	G	-1.5840
126	I	G	0.0000
127	K	G	-1.8922
128	R	G	-1.1330
129	T	G	0.0157
130	V	G	1.1652
131	A	G	0.5880
132	A	G	0.2327
133	P	G	0.0239
134	S	G	-0.0613
135	V	G	0.0000
136	F	G	1.4578
137	I	G	1.3210
138	F	G	1.4918
139	P	G	0.0618
140	P	G	0.0000
141	S	G	-1.7491
142	D	G	-3.2051
143	E	G	-3.4480
144	Q	G	-2.5081
145	L	G	-2.5245
146	K	G	-3.0338
147	S	G	-1.9156
148	G	G	-1.5545
149	T	G	-1.2138
150	A	G	0.0000
151	S	G	0.0362
152	V	G	0.0000
153	V	G	0.7031
154	C	G	0.0000
155	L	G	0.7371
156	L	G	0.0000
157	N	G	-0.4195
158	N	G	-1.1771
159	F	G	0.0000
160	Y	G	-0.8432
161	P	G	-1.4705
162	R	G	-2.7467
163	E	G	-3.1340
164	A	G	-2.2062
165	K	G	-2.1297
166	V	G	-0.8874
167	S	G	-0.1963
168	W	G	0.0000
169	Y	G	0.0031
170	V	G	0.0000
171	D	G	-2.1020
172	N	G	-1.2844
173	A	G	-0.1615
174	L	G	0.9626
175	Q	G	-0.0049
176	S	G	-0.2959
177	G	G	-0.9879
178	N	G	-0.9273
179	S	G	-1.3829
180	Q	G	-2.2905
181	E	G	-2.2905
182	S	G	-1.2572
183	V	G	-0.6977
184	T	G	-1.1884
185	E	G	-2.2511
186	Q	G	0.0000
187	D	G	-2.3770
188	S	G	-2.3772
189	K	G	-2.6632
190	D	G	-1.8426
191	S	G	0.0000
192	T	G	0.0000
193	Y	G	0.0000
194	S	G	-0.9053
195	L	G	-0.8455
196	S	G	-0.3502
197	S	G	0.0000
198	T	G	-0.6215
199	L	G	0.0000
200	T	G	-0.5306
201	L	G	-0.7102
202	S	G	-1.3398
203	K	G	-2.2834
204	A	G	-2.0114
205	D	G	-2.7738
206	Y	G	0.0000
207	E	G	-3.1211
208	K	G	-3.5952
209	H	G	-2.9797
210	K	G	-3.0867
211	V	G	-1.3854
212	Y	G	0.0000
213	A	G	-0.5051
214	C	G	0.0000
215	E	G	-0.7062
216	V	G	0.0000
217	T	G	-1.0684
218	Q	G	-1.3038
219	G	G	-1.0534
220	T	G	-0.4239
221	T	G	-0.2714
222	S	G	-0.3923
223	V	G	0.0842
224	T	G	-0.2458
225	K	G	-0.4561
226	S	G	-0.3343
227	F	G	0.0000
228	N	G	-2.0910
229	R	G	-2.4046
230	G	G	-1.9488
231	E	G	-2.5447