Project name: FEFEFEGSKGH12

Chain sequence(s)	A: FEFEFEGSKGH; C: FEFEFEGSKGH; B: FEFEFEGSKGH; E: FEFEFEGSKGH; D: FEFEFEGSKGH; G: FEFEFEGSKGH; F: FEFEFEGSKGH; I: FEFEFEGSKGH; H: FEFEFEGSKGH; K: FEFEFEGSKGH; J: FEFEFEGSKGH; L: FEFEFEGSKGH
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:06:19)
[INFO]       Main:     Simulation completed successfully.                                          (00:06:23)

• Minimal score value: -4.3362
• Maximal score value: 1.2851
• Average score: -2.5151
• Total score value: -331.9889

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	F	A	0.9947
2	E	A	-1.9126
3	F	A	-1.8762
4	E	A	-3.7372
5	F	A	-3.2436
6	E	A	-3.6061
7	G	A	-2.8902
8	S	A	-3.0273
9	K	A	-3.3279
10	G	A	-2.9413
11	H	A	-2.4353
1	F	B	0.7206
2	E	B	-2.2905
3	F	B	-2.2207
4	E	B	-4.3362
5	F	B	-3.0793
6	E	B	-4.1385
7	G	B	-3.0376
8	S	B	-3.1404
9	K	B	-3.5871
10	G	B	-2.9968
11	H	B	-2.4820
1	F	C	0.0149
2	E	C	-2.6296
3	F	C	0.0000
4	E	C	-4.2351
5	F	C	-2.9632
6	E	C	-3.7692
7	G	C	-2.7466
8	S	C	-2.7395
9	K	C	-3.2285
10	G	C	-2.7706
11	H	C	-2.3251
1	F	D	-0.0882
2	E	D	-2.5756
3	F	D	0.0000
4	E	D	-4.0400
5	F	D	-2.8502
6	E	D	-3.5171
7	G	D	-2.6114
8	S	D	-2.4664
9	K	D	-2.9858
10	G	D	-2.6365
11	H	D	-2.2761
1	F	E	1.0029
2	E	E	-1.6572
3	F	E	-1.9834
4	E	E	-3.5539
5	F	E	-2.8522
6	E	E	-3.5520
7	G	E	-2.6628
8	S	E	-2.8970
9	K	E	-3.3480
10	G	E	-2.9563
11	H	E	-2.4390
1	F	F	1.2851
2	E	F	-1.5569
3	F	F	-1.7797
4	E	F	-3.5931
5	F	F	-2.8071
6	E	F	-3.5050
7	G	F	-2.7996
8	S	F	-2.9266
9	K	F	-3.4688
10	G	F	-3.2051
11	H	F	-2.4636
1	F	G	1.1225
2	E	G	-1.5987
3	F	G	-1.9506
4	E	G	-3.9429
5	F	G	-2.9734
6	E	G	-3.7748
7	G	G	-2.8171
8	S	G	-2.8135
9	K	G	-3.0876
10	G	G	-2.7502
11	H	G	-2.3308
1	F	H	0.2642
2	E	H	-2.3588
3	F	H	-2.1552
4	E	H	-3.9392
5	F	H	-2.8525
6	E	H	-3.8782
7	G	H	-2.8310
8	S	H	-2.6426
9	K	H	-3.1790
10	G	H	-2.7671
11	H	H	-2.3655
1	F	I	-0.3615
2	E	I	-2.7763
3	F	I	-2.4189
4	E	I	-4.1563
5	F	I	-2.9426
6	E	I	-3.7658
7	G	I	-2.8480
8	S	I	-2.8655
9	K	I	-3.1487
10	G	I	-2.8047
11	H	I	-2.3445
1	F	J	-0.1529
2	E	J	-2.6566
3	F	J	0.0000
4	E	J	-3.9438
5	F	J	-2.6555
6	E	J	-3.5063
7	G	J	-2.5869
8	S	J	-2.6854
9	K	J	-3.4097
10	G	J	-2.6023
11	H	J	-2.2939
1	F	K	0.9792
2	E	K	-1.8857
3	F	K	-2.0400
4	E	K	-3.8130
5	F	K	-2.8956
6	E	K	-3.6162
7	G	K	-2.5845
8	S	K	-2.6712
9	K	K	-3.3770
10	G	K	-3.0750
11	H	K	-2.4005
1	F	L	1.1321
2	E	L	-1.5822
3	F	L	-1.6804
4	E	L	-3.4222
5	F	L	-2.7705
6	E	L	-3.5557
7	G	L	-2.8134
8	S	L	-2.6835
9	K	L	-3.4677
10	G	L	-3.0677
11	H	L	-2.3995