Project name: E8bM5

Chain sequence(s)	A: ALVANASLTSGASTLQQFTAKSENSSQYSFPCAYYLQQSLSDGLIVSSLYLKLDRAQFTNMPTGANYQNARYFTFWVGAGTSFNLSTLTEPTITPNTTQWNAFAPALDYSGAPPFIYDASSVVTIYFEPTSGRLESYKPSLTDNWSQTYNPGTVTLCVKTVRVQLRSQGTFSTLVCYNFRCQNTGIFNNNATAGTMTLGPIKFSCPALSTANAP
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:04)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:05)

• Minimal score value: -2.3386
• Maximal score value: 2.5241
• Average score: -0.4102
• Total score value: -87.7725

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	1.2771
2	L	A	2.0883
3	V	A	1.7505
4	A	A	0.3478
5	N	A	-1.0990
6	A	A	0.0000
7	S	A	-0.6585
8	L	A	0.0000
9	T	A	-0.6449
10	S	A	0.0000
11	G	A	-0.8379
12	A	A	-0.5803
13	S	A	-0.5528
14	T	A	-0.7889
15	L	A	0.0000
16	Q	A	-1.8269
17	Q	A	-1.7151
18	F	A	-0.9119
19	T	A	-0.6057
20	A	A	0.0000
21	K	A	-0.6030
22	S	A	0.0000
23	E	A	0.0000
24	N	A	0.0000
25	S	A	-0.7724
26	S	A	0.0000
27	Q	A	-0.4554
28	Y	A	0.0000
29	S	A	-0.6223
30	F	A	0.0000
31	P	A	-0.6303
32	C	A	0.0000
33	A	A	0.0000
34	Y	A	0.0000
35	Y	A	-0.2827
36	L	A	0.0000
37	Q	A	-0.7008
38	Q	A	0.0000
39	S	A	-0.2667
40	L	A	0.0000
41	S	A	-0.8643
42	D	A	-1.4143
43	G	A	-0.4956
44	L	A	0.2456
45	I	A	0.0000
46	V	A	0.8902
47	S	A	0.0000
48	S	A	-0.5563
49	L	A	0.0000
50	Y	A	-0.0003
51	L	A	0.0000
52	K	A	-0.5228
53	L	A	0.0000
54	D	A	-0.7251
55	R	A	-0.8640
56	A	A	-0.4498
57	Q	A	-0.6932
58	F	A	0.0000
59	T	A	-0.8845
60	N	A	-1.3262
61	M	A	-0.6781
62	P	A	-0.5872
63	T	A	-0.8645
64	G	A	-0.8397
65	A	A	-1.0408
66	N	A	-1.5419
67	Y	A	-0.9808
68	Q	A	-1.4348
69	N	A	-2.0088
70	A	A	0.0000
71	R	A	-1.5223
72	Y	A	-0.7782
73	F	A	0.0000
74	T	A	0.0000
75	F	A	0.0000
76	W	A	0.0000
77	V	A	0.0000
78	G	A	-0.3724
79	A	A	-0.9829
80	G	A	-1.1553
81	T	A	-0.7904
82	S	A	-0.2538
83	F	A	0.0000
84	N	A	-0.6526
85	L	A	0.0000
86	S	A	0.0000
87	T	A	-0.5931
88	L	A	0.0000
89	T	A	-1.0887
90	E	A	-1.9745
91	P	A	-1.2542
92	T	A	-1.0106
93	I	A	0.0000
94	T	A	-1.0438
95	P	A	-1.2104
96	N	A	-1.6745
97	T	A	-1.0488
98	T	A	-1.4876
99	Q	A	-1.9222
100	W	A	0.0000
101	N	A	-1.6114
102	A	A	-0.8012
103	F	A	0.0000
104	A	A	-0.2933
105	P	A	0.0000
106	A	A	0.0000
107	L	A	0.5464
108	D	A	0.2134
109	Y	A	1.0095
110	S	A	0.0823
111	G	A	-0.2742
112	A	A	-0.2929
113	P	A	-0.3505
114	P	A	-0.0273
115	F	A	0.4623
116	I	A	0.9252
117	Y	A	1.1338
118	D	A	0.4134
119	A	A	0.5104
120	S	A	0.9523
121	S	A	1.0207
122	V	A	2.3547
123	V	A	2.5241
124	T	A	1.1812
125	I	A	0.0000
126	Y	A	0.1270
127	F	A	0.0450
128	E	A	-0.7855
129	P	A	0.0000
130	T	A	-0.4189
131	S	A	-0.7577
132	G	A	-1.0794
133	R	A	-1.4623
134	L	A	0.0881
135	E	A	-0.3043
136	S	A	-0.3606
137	Y	A	-0.8819
138	K	A	-1.7255
139	P	A	0.0000
140	S	A	-0.5562
141	L	A	-0.9297
142	T	A	-1.2691
143	D	A	-2.3386
144	N	A	-1.9621
145	W	A	0.0000
146	S	A	-1.4792
147	Q	A	-1.9134
148	T	A	-1.1720
149	Y	A	-1.2651
150	N	A	-1.5443
151	P	A	0.0000
152	G	A	-1.5114
153	T	A	-1.3843
154	V	A	0.0000
155	T	A	-0.5772
156	L	A	0.0000
157	C	A	0.0000
158	V	A	0.0000
159	K	A	-0.6883
160	T	A	-0.1241
161	V	A	0.0000
162	R	A	0.1086
163	V	A	0.0000
164	Q	A	-0.0710
165	L	A	-0.5462
166	R	A	-1.9237
167	S	A	-1.6113
168	Q	A	-1.9003
169	G	A	-1.4735
170	T	A	-0.5102
171	F	A	0.6477
172	S	A	0.3696
173	T	A	0.0000
174	L	A	0.0000
175	V	A	0.0000
176	C	A	0.0000
177	Y	A	0.0000
178	N	A	0.0000
179	F	A	0.0000
180	R	A	-0.9469
181	C	A	0.0000
182	Q	A	-2.1117
183	N	A	-2.3044
184	T	A	-1.6443
185	G	A	0.0000
186	I	A	0.0000
187	F	A	0.0000
188	N	A	-1.1639
189	N	A	-1.2640
190	N	A	-1.5971
191	A	A	0.0000
192	T	A	-0.8846
193	A	A	-1.0213
194	G	A	0.0000
195	T	A	-0.7267
196	M	A	0.0000
197	T	A	-0.3706
198	L	A	0.0000
199	G	A	-0.5865
200	P	A	-0.5991
201	I	A	0.0000
202	K	A	-1.4886
203	F	A	-0.5709
204	S	A	0.1891
205	C	A	0.0000
206	P	A	0.1029
207	A	A	0.0000
208	L	A	0.3265
209	S	A	0.2742
210	T	A	-0.0709
211	A	A	-0.0612
212	N	A	-0.1233
213	A	A	-0.0454
214	P	A	-0.0761