Project name: WH24

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGSISSHNDMSWYRQAPGKQRELVAFIASGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCNSRTYDGEKTYWGQGTTVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:52)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:52)

• Minimal score value: -2.8842
• Maximal score value: 1.192
• Average score: -0.7204
• Total score value: -84.2812

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9929
2	V	H	-1.2742
3	Q	H	-1.1841
4	L	H	0.0000
5	V	H	1.1604
6	E	H	0.0000
7	S	H	-0.3370
8	G	H	-0.9850
9	G	H	-0.3448
11	G	H	0.2960
12	L	H	1.1920
13	V	H	-0.0126
14	Q	H	-1.3611
15	P	H	-1.4267
16	G	H	-1.4347
17	G	H	-0.9632
18	S	H	-0.9701
19	L	H	-0.7372
20	R	H	-1.7987
21	L	H	0.0000
22	S	H	-0.2823
23	C	H	0.0000
24	A	H	0.0402
25	A	H	-0.3522
26	S	H	-0.8549
27	G	H	-0.8787
28	S	H	-0.8819
29	I	H	0.0000
30	S	H	-1.5052
35	S	H	-1.2126
36	H	H	-1.3923
37	N	H	-1.1131
38	D	H	-1.0372
39	M	H	0.0000
40	S	H	0.0000
41	W	H	0.0000
42	Y	H	0.3819
43	R	H	0.0000
44	Q	H	-1.1287
45	A	H	0.0000
46	P	H	-1.0195
47	G	H	-1.4346
48	K	H	-2.1730
49	Q	H	-2.2745
50	R	H	-1.6322
51	E	H	-0.9166
52	L	H	0.5801
53	V	H	0.0000
54	A	H	0.0000
55	F	H	0.6698
56	I	H	0.0000
57	A	H	-0.7039
58	S	H	-1.3525
59	G	H	-1.0284
63	G	H	-0.6060
64	S	H	-0.2119
65	T	H	0.4357
66	Y	H	1.0955
67	Y	H	0.0301
68	A	H	-0.7456
69	D	H	-2.2719
70	S	H	-1.6918
71	V	H	0.0000
72	K	H	-2.3639
74	G	H	-1.6874
75	R	H	-1.4736
76	F	H	0.0000
77	T	H	-0.6421
78	I	H	0.0000
79	S	H	-0.4703
80	R	H	-1.1767
81	D	H	-1.7713
82	N	H	-2.3977
83	S	H	-1.8825
84	K	H	-2.5480
85	N	H	-2.0061
86	T	H	-1.0799
87	L	H	0.0000
88	Y	H	-0.4565
89	L	H	0.0000
90	Q	H	-1.1629
91	M	H	0.0000
92	N	H	-1.3094
93	S	H	-1.2246
94	L	H	0.0000
95	R	H	-2.1946
96	A	H	-1.6541
97	E	H	-2.1766
98	D	H	0.0000
99	T	H	-0.6030
100	A	H	0.0000
101	V	H	0.1756
102	Y	H	0.0000
103	Y	H	0.3378
104	C	H	0.0000
105	N	H	0.0000
106	S	H	0.0000
107	R	H	-1.5284
108	T	H	-1.3842
109	Y	H	-1.1562
110	D	H	-2.2614
113	G	H	-2.3386
114	E	H	-2.8842
115	K	H	-2.2736
116	T	H	-0.9689
117	Y	H	-0.5433
118	W	H	0.2569
119	G	H	0.0463
120	Q	H	-0.7514
121	G	H	0.0000
122	T	H	0.0000
123	T	H	0.0646
124	V	H	0.0000
125	T	H	0.0205
126	V	H	0.0000
127	S	H	-0.5909
128	S	H	-0.5785