Project name: 1d997f20259fcb0

Chain sequence(s)	A: AEAEAKAKAEAEAKAK; C: AEAEAKAKAEAEAKAK; B: AEAEAKAKAEAEAKAK; E: AEAEAKAKAEAEAKAK; D: AEAEAKAKAEAEAKAK; G: AEAEAKAKAEAEAKAK; F: AEAEAKAKAEAEAKAK; H: AEAEAKAKAEAEAKAK
Selected Chain(s)	A,C,B,E,D,G,F,H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:08:47)
[INFO]       Main:     Simulation completed successfully.                                          (00:08:49)

• Minimal score value: -3.7092
• Maximal score value: 0.0
• Average score: -2.308
• Total score value: -295.422

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-1.6537
2	E	A	-2.9318
3	A	A	-2.4774
4	E	A	-3.6964
5	A	A	-2.9883
6	K	A	-3.6355
7	A	A	-3.5403
8	K	A	-3.7092
9	A	A	-2.6602
10	E	A	-3.1224
11	A	A	-2.9410
12	E	A	-2.9906
13	A	A	-2.2778
14	K	A	-2.8831
15	A	A	0.0000
16	K	A	-3.1340
1	A	B	-2.2926
2	E	B	-3.1238
3	A	B	-1.9311
4	E	B	-3.2289
5	A	B	-2.7880
6	K	B	-3.0114
7	A	B	-2.3934
8	K	B	0.0000
9	A	B	-2.1638
10	E	B	-3.0272
11	A	B	0.0000
12	E	B	0.0000
13	A	B	-2.7744
14	K	B	-3.5077
15	A	B	-3.3661
16	K	B	-3.2235
1	A	C	-1.8480
2	E	C	-2.6751
3	A	C	-2.3283
4	E	C	-3.1894
5	A	C	-3.1349
6	K	C	-3.1918
7	A	C	-2.8313
8	K	C	-2.3513
9	A	C	-2.7019
10	E	C	-2.7905
11	A	C	0.0000
12	E	C	0.0000
13	A	C	-2.2440
14	K	C	-2.7578
15	A	C	0.0000
16	K	C	-3.1634
1	A	D	-1.3637
2	E	D	-2.4934
3	A	D	-1.8353
4	E	D	-2.1995
5	A	D	-2.1032
6	K	D	-3.0506
7	A	D	-2.5149
8	K	D	-2.2547
9	A	D	-2.4423
10	E	D	-3.0688
11	A	D	0.0000
12	E	D	-2.8659
13	A	D	-2.4634
14	K	D	-3.0563
15	A	D	-2.8027
16	K	D	-2.9360
1	A	E	-1.7634
2	E	E	-2.5990
3	A	E	-2.2128
4	E	E	-2.4470
5	A	E	-2.5104
6	K	E	-3.1106
7	A	E	-2.7342
8	K	E	-2.1798
9	A	E	-2.5042
10	E	E	-3.1376
11	A	E	0.0000
12	E	E	0.0000
13	A	E	-2.5234
14	K	E	-3.1564
15	A	E	0.0000
16	K	E	-2.9497
1	A	F	-1.2589
2	E	F	-2.4669
3	A	F	-2.0449
4	E	F	-2.4132
5	A	F	-2.1724
6	K	F	-2.9659
7	A	F	-2.8008
8	K	F	-2.6284
9	A	F	-2.1064
10	E	F	-2.8940
11	A	F	0.0000
12	E	F	-3.2617
13	A	F	-2.4660
14	K	F	-3.2745
15	A	F	0.0000
16	K	F	-3.0993
1	A	G	-1.7791
2	E	G	-2.6477
3	A	G	-1.8710
4	E	G	-2.4213
5	A	G	-2.5284
6	K	G	-2.9353
7	A	G	-2.1716
8	K	G	0.0000
9	A	G	-2.4351
10	E	G	-2.9180
11	A	G	-2.2249
12	E	G	0.0000
13	A	G	-2.3735
14	K	G	-2.9770
15	A	G	-2.8080
16	K	G	-3.0302
1	A	H	-1.5829
2	E	H	-2.9075
3	A	H	-2.0816
4	E	H	-2.4858
5	A	H	-2.1883
6	K	H	-3.0809
7	A	H	-2.5488
8	K	H	0.0000
9	A	H	-2.1673
10	E	H	-2.8214
11	A	H	0.0000
12	E	H	-2.6456
13	A	H	-2.7217
14	K	H	-2.9417
15	A	H	-2.9464
16	K	H	-3.3672