Project name: fapc-abeta (cluster2(

Chain sequence(s)	A: AAGAGNQQSNTLTLG; B: LVFFAEDVGSNKGAIIGLMVGGVVIA
Selected Chain(s)	A,B
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:02)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:02)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:02)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:02)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:02)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:11)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:12)

• Minimal score value: -2.1375
• Maximal score value: 3.8156
• Average score: 1.0395
• Total score value: 42.619

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-0.6670
2	A	A	-0.0977
3	G	A	-0.2240
4	A	A	0.6369
5	G	A	0.0000
6	N	A	-0.9986
7	Q	A	-0.7358
8	Q	A	-0.0479
9	S	A	1.3283
10	N	A	2.4740
11	T	A	3.1213
12	L	A	3.4712
13	T	A	2.3673
14	L	A	2.0192
15	G	A	0.2931
17	L	B	2.9899
18	V	B	3.3135
19	F	B	3.2198
20	F	B	2.1070
21	A	B	-0.0005
22	E	B	-1.7004
23	D	B	-1.0270
24	V	B	0.3345
25	G	B	-0.7063
26	S	B	-1.0197
27	N	B	-2.1375
28	K	B	-2.0191
29	G	B	-0.2652
30	A	B	0.7083
31	I	B	2.7378
32	I	B	2.5703
33	G	B	1.6114
34	L	B	1.4145
35	M	B	1.5167
36	V	B	1.1575
37	G	B	0.8605
38	G	B	1.6287
39	V	B	2.9295
40	V	B	3.8156
41	I	B	3.6345
42	A	B	2.0044