Project name: 2099246fc211d34

Chain sequence(s)	L: IVMTQSPDSLAVSLGERATINCKSSESVSNDVAWYQQKPGQPPKLLINYAFHRFTGVPDRFSGSGYGTDFTLTISSLQAEDVAVYYCHQAYSSPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Selected Chain(s)	L
Distance of aggregation	5 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:28)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:28)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with L chain(s) selected             (00:00:28)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:28)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:28)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:05:07)
[INFO]       Main:     Simulation completed successfully.                                          (00:05:12)

• Minimal score value: -2.2014
• Maximal score value: 1.9208
• Average score: -0.2929
• Total score value: -62.381

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	I	L	0.8936
3	V	L	1.8768
4	M	L	0.0000
5	T	L	-0.0480
6	Q	L	0.0000
7	S	L	-0.1982
8	P	L	-0.4895
9	D	L	-1.8491
10	S	L	-0.6622
11	L	L	0.2499
12	A	L	0.0359
13	V	L	0.1884
14	S	L	-0.0763
15	L	L	0.6898
16	G	L	-0.3686
17	E	L	-1.9462
18	R	L	-2.1420
19	A	L	0.0000
20	T	L	-0.0375
21	I	L	0.0000
22	N	L	-0.3550
23	C	L	0.0000
24	K	L	-1.4700
25	S	L	-0.3219
26	S	L	-0.5508
27	E	L	-1.8919
28	S	L	-0.5221
29	V	L	0.0000
30	S	L	-0.1175
31	N	L	-0.3923
32	D	L	-0.7680
33	V	L	0.0000
34	A	L	-0.0184
35	W	L	0.0000
36	Y	L	0.2733
37	Q	L	-0.1433
38	Q	L	-0.4186
39	K	L	-0.4897
40	P	L	-0.3822
41	G	L	-0.6653
42	Q	L	-0.9905
43	P	L	-0.4520
44	P	L	-0.5463
45	K	L	-1.2574
46	L	L	0.0572
47	L	L	0.0000
48	I	L	0.0000
49	N	L	0.0603
50	Y	L	1.2824
51	A	L	0.0000
52	F	L	1.2535
53	H	L	-0.8789
54	R	L	-0.9140
55	F	L	0.4379
56	T	L	-0.0460
57	G	L	-0.4794
58	V	L	0.0000
59	P	L	-0.4933
60	D	L	-1.8731
61	R	L	-0.6308
62	F	L	0.0000
63	S	L	-0.1073
64	G	L	0.1048
65	S	L	0.0078
66	G	L	0.1202
67	Y	L	1.2859
68	G	L	0.1516
69	T	L	-0.1839
70	D	L	-0.9164
71	F	L	0.0000
72	T	L	-0.0581
73	L	L	0.0000
74	T	L	-0.0220
75	I	L	0.0000
76	S	L	-0.3569
77	S	L	-0.1802
78	L	L	0.0000
79	Q	L	-0.7565
80	A	L	-0.4086
81	E	L	-1.4961
82	D	L	0.0000
83	V	L	0.0000
84	A	L	0.0000
85	V	L	-0.0235
86	Y	L	0.0000
87	Y	L	0.2575
88	C	L	0.0000
89	H	L	0.1522
90	Q	L	0.0000
91	A	L	0.2311
92	Y	L	1.0058
93	S	L	0.0574
94	S	L	-0.1502
95	P	L	-0.0831
96	Y	L	1.1855
97	T	L	0.5738
98	F	L	1.9208
99	G	L	0.0000
100	Q	L	-1.1983
101	G	L	0.0000
102	T	L	0.0000
103	K	L	-1.4080
104	L	L	0.0000
105	E	L	-0.9892
106	I	L	0.0000
107	K	L	-1.3346
108	R	L	-0.8393
109	T	L	0.1461
110	V	L	1.7609
111	A	L	0.3405
112	A	L	0.0256
113	P	L	0.0000
114	S	L	-0.1715
115	V	L	0.3719
116	F	L	1.1810
117	I	L	0.6753
118	F	L	1.1290
119	P	L	0.1165
120	P	L	0.0000
121	S	L	-0.4286
122	D	L	-2.1410
123	E	L	-2.2014
124	Q	L	-0.5819
125	L	L	-0.1270
126	K	L	-1.6952
127	S	L	-0.5547
128	G	L	-0.2162
129	T	L	-0.1577
130	A	L	0.0000
131	S	L	-0.0518
132	V	L	0.0000
133	V	L	0.3880
134	C	L	0.0000
135	L	L	0.3380
136	L	L	0.0000
137	N	L	-0.6567
138	N	L	-0.6654
139	F	L	0.0000
140	Y	L	0.0000
141	P	L	-0.3384
142	R	L	-1.9437
143	E	L	-2.1114
144	A	L	-0.6348
145	K	L	-1.6625
146	V	L	-0.1733
147	Q	L	-0.2507
148	W	L	0.0000
149	K	L	-0.2775
150	V	L	0.0000
151	D	L	-1.4671
152	N	L	-1.5224
153	A	L	0.1004
154	L	L	1.4656
155	Q	L	-0.0722
156	S	L	-0.3574
157	G	L	-0.7390
158	N	L	-1.3718
159	S	L	-0.5270
160	Q	L	-1.5496
161	E	L	-2.0822
162	S	L	-0.4934
163	V	L	0.2775
164	T	L	-0.3426
165	E	L	-1.8310
166	Q	L	0.0000
167	D	L	-1.0158
168	S	L	-0.7775
169	K	L	-1.7920
170	D	L	-0.7206
171	S	L	0.0000
172	T	L	0.0000
173	Y	L	0.0000
174	S	L	-0.0950
175	L	L	0.0000
176	S	L	-0.0286
177	S	L	0.0000
178	T	L	0.0345
179	L	L	0.0000
180	T	L	-0.0197
181	L	L	0.1201
182	S	L	-0.2310
183	K	L	-0.6577
184	A	L	-0.3177
185	D	L	-1.4047
186	Y	L	0.0000
187	E	L	-2.0840
188	K	L	-2.0692
189	H	L	-0.7379
190	K	L	-0.9641
191	V	L	0.2979
192	Y	L	0.0000
193	A	L	-0.0244
194	C	L	0.0000
195	E	L	-0.3724
196	V	L	0.0000
197	T	L	-0.0704
198	H	L	0.0000
199	Q	L	-1.2252
200	G	L	-0.3103
201	L	L	0.2037
202	S	L	-0.2016
203	S	L	-0.2907
204	P	L	-0.1726
205	V	L	0.4127
206	T	L	-0.2306
207	K	L	-1.2638
208	S	L	-0.3653
209	F	L	0.0293
210	N	L	-0.8898
211	R	L	-0.7714
212	G	L	-0.8774
213	E	L	-1.7737
214	C	L	0.4018