Project name: 1B7

Chain sequence(s)	H: QVQLVESGGGLVQPGGSLRLSCVASGFTLDYYAIGWFRQAPGAEREFVGAINWRGDMTYYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAAEGRGTTGWGTNVEAYDYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:32)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:33)

• Minimal score value: -2.5105
• Maximal score value: 1.1872
• Average score: -0.7031
• Total score value: -88.5888

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.4181
2	V	H	-0.9811
3	Q	H	-0.7916
4	L	H	0.0000
5	V	H	1.1872
6	E	H	0.0000
7	S	H	-0.3667
8	G	H	-1.0958
9	G	H	-0.6607
11	G	H	0.0543
12	L	H	1.1319
13	V	H	0.0068
14	Q	H	-1.3357
15	P	H	-1.6057
16	G	H	-1.4150
17	G	H	-0.9039
18	S	H	-1.1734
19	L	H	-0.8355
20	R	H	-2.0215
21	L	H	0.0000
22	S	H	-0.1312
23	C	H	0.0000
24	V	H	0.7469
25	A	H	0.0000
26	S	H	-0.3989
27	G	H	-0.9963
28	F	H	-0.3324
29	T	H	-0.1383
30	L	H	0.0000
35	D	H	-0.5184
36	Y	H	0.5634
37	Y	H	-0.0096
38	A	H	0.0000
39	I	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.1266
45	A	H	-1.0788
46	P	H	-0.7180
47	G	H	-0.9901
48	A	H	-1.3606
49	E	H	-2.3585
50	R	H	-1.6429
51	E	H	-1.4094
52	F	H	0.0000
53	V	H	0.0000
54	G	H	0.0000
55	A	H	0.0000
56	I	H	0.0000
57	N	H	0.0000
58	W	H	-0.9217
59	R	H	-2.3751
62	G	H	-2.1316
63	D	H	-2.2364
64	M	H	-0.6789
65	T	H	-0.0011
66	Y	H	0.2146
67	Y	H	-0.5963
68	A	H	-1.3072
69	D	H	-2.3996
70	S	H	-1.7739
71	V	H	0.0000
72	K	H	-2.3794
74	G	H	-1.6646
75	R	H	-1.5895
76	F	H	0.0000
77	T	H	-0.7360
78	I	H	0.0000
79	S	H	-0.5807
80	R	H	-1.4478
81	D	H	-1.5082
82	N	H	-2.4540
83	A	H	-1.5648
84	K	H	-2.1984
85	N	H	-1.5587
86	T	H	0.0000
87	V	H	0.0000
88	Y	H	-0.3056
89	L	H	0.0000
90	Q	H	-1.1269
91	M	H	0.0000
92	N	H	-1.3551
93	S	H	-1.2375
94	L	H	0.0000
95	K	H	-2.5105
96	P	H	-2.0263
97	E	H	-2.4141
98	D	H	0.0000
99	T	H	-0.8190
100	A	H	0.0000
101	V	H	-0.2244
102	Y	H	0.0000
103	Y	H	-0.0269
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	E	H	-0.9192
108	G	H	-1.0950
109	R	H	-2.1348
110	G	H	-1.3252
111	T	H	-0.5875
111A	T	H	-0.4398
111B	G	H	-0.2455
111C	W	H	0.2621
112C	G	H	-0.5185
112B	T	H	-0.6999
112A	N	H	-1.5590
112	V	H	-1.2129
113	E	H	-2.1408
114	A	H	-1.6758
115	Y	H	0.0000
116	D	H	-1.3493
117	Y	H	-0.2517
118	W	H	0.0648
119	G	H	-0.0218
120	Q	H	-0.9936
121	G	H	-0.4373
122	T	H	-0.5277
123	Q	H	-0.7146
124	V	H	0.0000
125	T	H	-0.2181
126	V	H	0.0000
127	S	H	-0.8980
128	S	H	-0.8899