Project name: 2283675dc4847f2

Chain sequence(s)	C: EVQLVESGGGLVQPGGSLRLSCAASQYIGSRIAWFRQAPGKGRELVAYGASNSAGDSRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAARTSSASGYADDESIYDYWGQGTQVTVSS
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:50)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:50)

• Minimal score value: -2.7239
• Maximal score value: 0.9957
• Average score: -0.7971
• Total score value: -93.2586

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	C	-2.3531
2	V	C	-1.5319
3	Q	C	-1.5624
4	L	C	0.0000
5	V	C	0.6212
6	E	C	0.0000
7	S	C	-0.6830
8	G	C	-1.0065
9	G	C	-0.7864
10	G	C	-0.0680
11	L	C	0.9957
12	V	C	-0.0418
13	Q	C	-1.3374
14	P	C	-1.6450
15	G	C	-1.4681
16	G	C	-0.9772
17	S	C	-1.3555
18	L	C	-1.1276
19	R	C	-2.2971
20	L	C	0.0000
21	S	C	-0.4860
22	C	C	0.0000
23	A	C	-0.4772
24	A	C	0.0000
25	S	C	-1.1817
26	Q	C	-1.4923
27	Y	C	0.1253
28	I	C	-0.0503
29	G	C	-0.4269
30	S	C	-0.5479
31	R	C	-0.8029
32	I	C	0.0000
33	A	C	0.0000
34	W	C	0.0000
35	F	C	0.0000
36	R	C	-1.2288
37	Q	C	-1.7709
38	A	C	-1.7072
39	P	C	-1.1737
40	G	C	-1.6565
41	K	C	-2.7239
42	G	C	-2.2788
43	R	C	-2.4589
44	E	C	-2.6197
45	L	C	-1.3826
46	V	C	0.0000
47	A	C	0.0000
48	Y	C	-0.1968
49	G	C	-0.4625
50	A	C	-0.5810
51	S	C	-0.6765
52	N	C	-1.0616
53	S	C	-0.7351
54	A	C	-0.8801
55	G	C	-0.8867
56	D	C	-1.0257
57	S	C	-0.9110
58	R	C	-0.9223
59	F	C	0.0000
60	T	C	-0.9970
61	I	C	0.0000
62	S	C	-0.6948
63	R	C	-1.2451
64	D	C	-1.7601
65	N	C	-1.9863
66	A	C	-1.5039
67	K	C	-2.5680
68	R	C	-2.2044
69	M	C	-1.1737
70	V	C	0.0000
71	Y	C	-0.7114
72	L	C	0.0000
73	Q	C	-1.6532
74	M	C	0.0000
75	N	C	-1.4941
76	S	C	-1.2704
77	L	C	0.0000
78	R	C	-2.4787
79	A	C	-1.8331
80	E	C	-2.2864
81	D	C	0.0000
82	T	C	-0.9174
83	A	C	0.0000
84	V	C	-0.4442
85	Y	C	0.0000
86	Y	C	-0.2918
87	C	C	0.0000
88	A	C	0.0000
89	A	C	0.0000
90	R	C	0.0000
91	T	C	-0.5548
92	S	C	-0.5145
93	S	C	-0.3235
94	A	C	-0.2091
95	S	C	-0.0810
96	G	C	-0.2145
97	Y	C	0.2579
98	A	C	-0.5999
99	D	C	-2.1078
100	D	C	-1.6947
101	E	C	-1.8531
102	S	C	-0.9919
103	I	C	-0.6491
104	Y	C	0.0000
105	D	C	-1.3974
106	Y	C	-0.7959
107	W	C	-0.1847
108	G	C	-0.2383
109	Q	C	-0.9084
110	G	C	0.0000
111	T	C	-0.7413
112	Q	C	-0.9938
113	V	C	0.0000
114	T	C	-0.3147
115	V	C	0.0000
116	S	C	-0.7908
117	S	C	-0.5390