Project name: 1346

Chain sequence(s)	H: EVQLLESGGGSVQPGGSLRLSCAASGVTYSHYWLGWFRQAPGKEREGVAAIYTNDGTTYYADSVKGRFTISLDNPKNTLYLQMSSLTAEDTAVYYCALRPNDGSWFSPLQPYHYNYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:42)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:43)

• Minimal score value: -3.4669
• Maximal score value: 1.6198
• Average score: -0.7309
• Total score value: -92.8235

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9635
2	V	H	-1.2747
3	Q	H	-1.2144
4	L	H	0.0000
5	L	H	0.6374
6	E	H	0.0000
7	S	H	-0.6727
8	G	H	-1.1764
9	G	H	-1.1937
11	G	H	-0.9434
12	S	H	-0.7807
13	V	H	-0.7613
14	Q	H	-1.5531
15	P	H	-1.2078
16	G	H	-1.1215
17	G	H	-0.9128
18	S	H	-0.9887
19	L	H	-1.1284
20	R	H	-2.0201
21	L	H	0.0000
22	S	H	-0.3682
23	C	H	0.0000
24	A	H	-0.2462
25	A	H	-0.5158
26	S	H	-0.6943
27	G	H	-0.7968
28	V	H	-0.1899
29	T	H	0.3012
30	Y	H	0.2200
35	S	H	-0.7021
36	H	H	-1.4791
37	Y	H	0.0000
38	W	H	0.0000
39	L	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.9833
45	A	H	-1.8460
46	P	H	-1.3538
47	G	H	-1.8150
48	K	H	-3.2667
49	E	H	-3.4669
50	R	H	-2.4325
51	E	H	-2.4423
52	G	H	-1.0416
53	V	H	0.0000
54	A	H	0.0000
55	A	H	0.0000
56	I	H	0.0000
57	Y	H	0.0000
58	T	H	-1.0686
59	N	H	-1.5738
62	D	H	-2.2979
63	G	H	-1.3184
64	T	H	-0.6041
65	T	H	-0.1226
66	Y	H	0.1734
67	Y	H	-0.6540
68	A	H	-1.3518
69	D	H	-2.4446
70	S	H	-1.7887
71	V	H	0.0000
72	K	H	-2.5400
74	G	H	-1.7256
75	R	H	-1.5185
76	F	H	0.0000
77	T	H	-0.7270
78	I	H	0.0000
79	S	H	-0.2002
80	L	H	-0.6079
81	D	H	-1.5099
82	N	H	-2.2722
83	P	H	-1.8746
84	K	H	-2.5745
85	N	H	-1.9613
86	T	H	-1.0695
87	L	H	0.0000
88	Y	H	-0.3239
89	L	H	0.0000
90	Q	H	-1.0440
91	M	H	0.0000
92	S	H	-0.8794
93	S	H	-0.8550
94	L	H	0.0000
95	T	H	-1.1382
96	A	H	-1.1553
97	E	H	-1.8546
98	D	H	0.0000
99	T	H	-0.8234
100	A	H	0.0000
101	V	H	-0.5224
102	Y	H	0.0000
103	Y	H	-0.2611
104	C	H	0.0000
105	A	H	0.0000
106	L	H	0.0000
107	R	H	0.0000
108	P	H	-1.0976
109	N	H	-1.9081
110	D	H	-2.2740
111	G	H	-1.2072
111A	S	H	-0.0910
111B	W	H	1.3267
111C	F	H	1.6198
112D	S	H	1.0280
112C	P	H	0.0000
112B	L	H	0.3404
112A	Q	H	-0.5039
112	P	H	-0.5024
113	Y	H	0.6510
114	H	H	-0.2957
115	Y	H	0.0000
116	N	H	-0.8992
117	Y	H	-0.4533
118	W	H	-0.0344
119	G	H	-0.1856
120	Q	H	-0.9579
121	G	H	-0.5498
122	T	H	0.0000
123	Q	H	-1.3001
124	V	H	0.0000
125	T	H	-0.8711
126	V	H	0.0000
127	S	H	-0.9811
128	S	H	-0.7923