Project name: 22cb300f4420397

Chain sequence(s)	A: GGGGSGGGGSGGGGS; C: GGGGSGGGGSGGGGS; B: GGGGSGGGGSGGGGS; E: GGGGSGGGGSGGGGS; D: GGGGSGGGGSGGGGS; G: GGGGSGGGGSGGGGS; F: GGGGSGGGGSGGGGS; I: GGGGSGGGGSGGGGS; H: GGGGSGGGGSGGGGS; K: GGGGSGGGGSGGGGS; J: GGGGSGGGGSGGGGS; M: GGGGSGGGGSGGGGS; L: GGGGSGGGGSGGGGS; O: GGGGSGGGGSGGGGS; N: GGGGSGGGGSGGGGS; Q: GGGGSGGGGSGGGGS; P: GGGGSGGGGSGGGGS; S: GGGGSGGGGSGGGGS; R: GGGGSGGGGSGGGGS; T: GGGGSGGGGSGGGGS
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,M,L,O,N,Q,P,S,R,T
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:07)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:12)

• Minimal score value: -1.7256
• Maximal score value: 0.0
• Average score: -0.7775
• Total score value: -233.2445

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-1.0663
2	G	A	-1.0222
3	G	A	0.0000
4	G	A	-0.7911
5	S	A	0.0000
6	G	A	-0.5460
7	G	A	-0.6785
8	G	A	0.0000
9	G	A	-0.7710
10	S	A	0.0000
11	G	A	0.0000
12	G	A	0.0000
13	G	A	0.0000
14	G	A	0.0000
15	S	A	-1.3018
1	G	B	-1.0303
2	G	B	0.0000
3	G	B	0.0000
4	G	B	0.0000
5	S	B	0.0000
6	G	B	0.0000
7	G	B	0.0000
8	G	B	0.0000
9	G	B	0.0000
10	S	B	0.0000
11	G	B	0.0000
12	G	B	0.0000
13	G	B	0.0000
14	G	B	0.0000
15	S	B	-1.1574
1	G	C	-1.1437
2	G	C	-1.1560
3	G	C	-0.9294
4	G	C	-0.6117
5	S	C	-0.6478
6	G	C	-0.6944
7	G	C	-0.9254
8	G	C	-0.9602
9	G	C	-0.6179
10	S	C	-0.6472
11	G	C	-0.7334
12	G	C	-0.8453
13	G	C	-1.1084
14	G	C	-1.0603
15	S	C	-0.8882
1	G	D	-1.1494
2	G	D	-1.1490
3	G	D	-1.1336
4	G	D	0.0000
5	S	D	-0.7715
6	G	D	0.0000
7	G	D	-1.0465
8	G	D	-1.0981
9	G	D	0.0000
10	S	D	-0.8550
11	G	D	-0.9463
12	G	D	-1.0327
13	G	D	-1.2757
14	G	D	-1.2519
15	S	D	-1.0157
1	G	E	-1.0822
2	G	E	-1.1249
3	G	E	-1.1341
4	G	E	-1.2310
5	S	E	-0.9689
6	G	E	-1.0194
7	G	E	-1.1069
8	G	E	-1.0926
9	G	E	-1.2535
10	S	E	-0.9197
11	G	E	-0.9542
12	G	E	-0.9650
13	G	E	-1.0531
14	G	E	-1.0584
15	S	E	-0.8248
1	G	F	-1.1688
2	G	F	0.0000
3	G	F	0.0000
4	G	F	0.0000
5	S	F	0.0000
6	G	F	0.0000
7	G	F	0.0000
8	G	F	-1.1539
9	G	F	-1.1537
10	S	F	0.0000
11	G	F	-0.9069
12	G	F	0.0000
13	G	F	-1.1631
14	G	F	-1.1993
15	S	F	-1.0410
1	G	G	-1.0756
2	G	G	-1.0904
3	G	G	-1.0997
4	G	G	-1.1850
5	S	G	-0.8985
6	G	G	-1.0253
7	G	G	-1.0670
8	G	G	-1.0341
9	G	G	-1.1319
10	S	G	-0.9642
11	G	G	-0.9862
12	G	G	-0.9475
13	G	G	-1.0856
14	G	G	-1.0020
15	S	G	-0.8495
1	G	H	-1.1919
2	G	H	0.0000
3	G	H	-1.0296
4	G	H	-0.8507
5	S	H	0.0000
6	G	H	-0.7770
7	G	H	-0.8909
8	G	H	-0.8967
9	G	H	-0.8185
10	S	H	-0.8134
11	G	H	-0.7894
12	G	H	-0.7722
13	G	H	0.0000
14	G	H	-0.9342
15	S	H	-0.8872
1	G	I	-1.2906
2	G	I	0.0000
3	G	I	-0.8561
4	G	I	-0.5992
5	S	I	0.0000
6	G	I	-0.5639
7	G	I	-0.6805
8	G	I	-0.7113
9	G	I	-0.6102
10	S	I	-0.6440
11	G	I	-0.6291
12	G	I	-0.6556
13	G	I	0.0000
14	G	I	-0.8680
15	S	I	-0.8712
1	G	J	-1.5391
2	G	J	0.0000
3	G	J	-0.8580
4	G	J	-0.6669
5	S	J	0.0000
6	G	J	-0.6460
7	G	J	-0.6863
8	G	J	-0.6132
9	G	J	-0.6645
10	S	J	0.0000
11	G	J	-0.6020
12	G	J	-0.7781
13	G	J	0.0000
14	G	J	-0.8569
15	S	J	-0.8589
1	G	K	-1.5611
2	G	K	-1.3925
3	G	K	-1.0931
4	G	K	0.0000
5	S	K	-0.5755
6	G	K	0.0000
7	G	K	-0.8171
8	G	K	-0.8602
9	G	K	0.0000
10	S	K	-0.6073
11	G	K	0.0000
12	G	K	-0.8466
13	G	K	-0.9926
14	G	K	-0.9907
15	S	K	-0.9308
1	G	L	-1.6500
2	G	L	0.0000
3	G	L	-1.1439
4	G	L	-0.8898
5	S	L	0.0000
6	G	L	-0.7635
7	G	L	0.0000
8	G	L	-0.7837
9	G	L	-0.7799
10	S	L	0.0000
11	G	L	-0.6572
12	G	L	-0.8855
13	G	L	0.0000
14	G	L	-0.9936
15	S	L	-0.9798
1	G	M	-1.4251
2	G	M	-1.4592
3	G	M	-1.2183
4	G	M	-0.6893
5	S	M	-0.7117
6	G	M	-0.8037
7	G	M	-0.9483
8	G	M	-0.9417
9	G	M	-0.7238
10	S	M	-0.7006
11	G	M	-0.8141
12	G	M	-0.9035
13	G	M	-1.0859
14	G	M	-1.0999
15	S	M	-0.8623
1	G	N	-1.2271
2	G	N	-1.2264
3	G	N	0.0000
4	G	N	-0.9160
5	S	N	-0.7599
6	G	N	-0.6324
7	G	N	-0.8023
8	G	N	0.0000
9	G	N	-0.8252
10	S	N	-0.7862
11	G	N	0.0000
12	G	N	-0.7702
13	G	N	-1.1413
14	G	N	0.0000
15	S	N	-1.3339
1	G	O	-1.1246
2	G	O	-1.2357
3	G	O	0.0000
4	G	O	-0.7507
5	S	O	-0.7603
6	G	O	0.0000
7	G	O	-0.8633
8	G	O	-0.9296
9	G	O	-0.8094
10	S	O	-0.7064
11	G	O	0.0000
12	G	O	-0.9037
13	G	O	-1.2292
14	G	O	0.0000
15	S	O	-1.2244
1	G	P	-1.2178
2	G	P	-1.1486
3	G	P	-1.0902
4	G	P	0.0000
5	S	P	-0.6580
6	G	P	-0.7045
7	G	P	-0.7850
8	G	P	-0.8728
9	G	P	-0.8617
10	S	P	-0.6212
11	G	P	-0.7685
12	G	P	0.0000
13	G	P	-1.0501
14	G	P	-1.3417
15	S	P	-1.0753
1	G	Q	-1.6168
2	G	Q	-1.4723
3	G	Q	-1.2688
4	G	Q	0.0000
5	S	Q	-0.7970
6	G	Q	-0.9172
7	G	Q	-1.0281
8	G	Q	-0.9705
9	G	Q	-1.0302
10	S	Q	-0.8161
11	G	Q	-0.8630
12	G	Q	0.0000
13	G	Q	-1.1946
14	G	Q	-1.2721
15	S	Q	-0.9871
1	G	R	-1.5947
2	G	R	-1.7256
3	G	R	0.0000
4	G	R	-1.1141
5	S	R	-0.9887
6	G	R	-0.9840
7	G	R	-1.2323
8	G	R	0.0000
9	G	R	-1.0392
10	S	R	-0.9804
11	G	R	-0.8685
12	G	R	-1.1159
13	G	R	-1.3167
14	G	R	-1.2148
15	S	R	-0.9533
1	G	S	-1.4244
2	G	S	-1.5880
3	G	S	-1.4703
4	G	S	-1.1478
5	S	S	-1.0440
6	G	S	-1.0181
7	G	S	-1.2041
8	G	S	-1.3138
9	G	S	-1.0367
10	S	S	-0.9905
11	G	S	-1.0460
12	G	S	-1.1426
13	G	S	-1.3048
14	G	S	-1.1318
15	S	S	-0.7795
1	G	T	-1.5980
2	G	T	-1.5654
3	G	T	-1.5379
4	G	T	0.0000
5	S	T	-0.9305
6	G	T	-1.1120
7	G	T	-1.1941
8	G	T	-1.3288
9	G	T	-1.1571
10	S	T	-0.9170
11	G	T	-1.0895
12	G	T	-1.1956
13	G	T	-1.2583
14	G	T	-1.2869
15	S	T	-0.8551