| Chain sequence(s) |
A: PTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPSPLYSVEFSEEPFGVIVHRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPIEPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | WN804A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 2.27124 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:01)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:01)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:01)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:01)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:01)
[INFO] FoldX: Building mutant model (00:05:23)
[INFO] FoldX: Starting FoldX energy minimalization (00:05:41)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:10:57)
[INFO] Main: Simulation completed successfully. (00:11:10)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 79 | P | A | -0.9303 | |
| 80 | T | A | -1.1238 | |
| 81 | Q | A | -1.6128 | |
| 82 | C | A | -1.2461 | |
| 83 | D | A | -2.0614 | |
| 84 | V | A | -1.1860 | |
| 85 | P | A | -0.9249 | |
| 86 | P | A | -0.7309 | |
| 87 | N | A | -1.0720 | |
| 88 | S | A | -0.5899 | |
| 89 | R | A | -0.6352 | |
| 90 | F | A | 0.0000 | |
| 91 | D | A | -0.3432 | |
| 92 | C | A | 0.0000 | |
| 93 | A | A | -0.6160 | |
| 94 | P | A | -0.6351 | |
| 95 | D | A | -1.1543 | |
| 96 | K | A | -1.7956 | |
| 97 | A | A | -0.7915 | |
| 98 | I | A | -0.9845 | |
| 99 | T | A | -1.4781 | |
| 100 | Q | A | -2.2860 | |
| 101 | E | A | -3.2258 | |
| 102 | Q | A | -2.4976 | |
| 103 | C | A | 0.0000 | |
| 104 | E | A | -3.0742 | |
| 105 | A | A | -2.0138 | |
| 106 | R | A | -1.5705 | |
| 107 | G | A | -1.2777 | |
| 108 | C | A | 0.0000 | |
| 109 | C | A | 0.0000 | |
| 110 | Y | A | -0.2072 | |
| 111 | I | A | 0.5296 | |
| 112 | P | A | -0.1502 | |
| 113 | A | A | -0.9426 | |
| 114 | K | A | -2.1450 | |
| 115 | Q | A | -2.1050 | |
| 122 | M | A | 0.2978 | |
| 123 | G | A | -0.3325 | |
| 124 | Q | A | -0.5433 | |
| 125 | P | A | 0.0000 | |
| 126 | W | A | 0.6744 | |
| 127 | C | A | 0.0000 | |
| 128 | F | A | 0.0000 | |
| 129 | F | A | 0.0000 | |
| 130 | P | A | 0.0000 | |
| 131 | P | A | -0.6648 | |
| 132 | S | A | -0.8192 | |
| 133 | Y | A | 0.0000 | |
| 134 | P | A | -0.6720 | |
| 135 | S | A | -0.7438 | |
| 136 | Y | A | 0.0000 | |
| 137 | K | A | -2.3194 | |
| 138 | L | A | 0.0000 | |
| 139 | E | A | -2.0233 | |
| 140 | N | A | -1.3179 | |
| 141 | L | A | -0.2784 | |
| 142 | S | A | -0.2764 | |
| 143 | S | A | -0.5215 | |
| 144 | S | A | -0.8001 | |
| 145 | E | A | -1.5464 | |
| 146 | M | A | -0.3045 | |
| 147 | G | A | 0.0000 | |
| 148 | Y | A | 0.1690 | |
| 149 | T | A | -0.1586 | |
| 150 | A | A | 0.0000 | |
| 151 | T | A | -1.0166 | |
| 152 | L | A | 0.0000 | |
| 153 | T | A | -0.5600 | |
| 154 | R | A | 0.0000 | |
| 155 | T | A | -0.1664 | |
| 156 | T | A | -0.1256 | |
| 157 | P | A | -0.4375 | |
| 158 | T | A | -0.3113 | |
| 159 | F | A | -0.0742 | |
| 160 | F | A | 0.0000 | |
| 161 | P | A | -1.1823 | |
| 162 | K | A | -1.9449 | |
| 163 | D | A | -0.9678 | |
| 164 | I | A | -0.2872 | |
| 165 | L | A | 0.3633 | |
| 166 | T | A | -0.0891 | |
| 167 | L | A | 0.0000 | |
| 168 | R | A | -1.1644 | |
| 169 | L | A | 0.0000 | |
| 170 | D | A | 0.0000 | |
| 171 | V | A | 0.0000 | |
| 172 | M | A | 0.0052 | |
| 173 | M | A | -0.4321 | |
| 174 | E | A | -0.9223 | |
| 175 | T | A | -1.4004 | |
| 176 | E | A | -2.2395 | |
| 177 | N | A | -1.5493 | |
| 178 | R | A | -1.2127 | |
| 179 | L | A | 0.0000 | |
| 180 | H | A | -0.1831 | |
| 181 | F | A | 0.0000 | |
| 182 | T | A | 0.0000 | |
| 183 | I | A | 0.0000 | |
| 184 | K | A | -1.4183 | |
| 185 | D | A | 0.0000 | |
| 186 | P | A | -1.3543 | |
| 187 | A | A | -1.2395 | |
| 188 | N | A | -2.3559 | |
| 189 | R | A | -2.7654 | |
| 190 | R | A | -1.7435 | |
| 191 | Y | A | -0.7647 | |
| 192 | E | A | -0.9170 | |
| 193 | V | A | 0.0000 | |
| 194 | P | A | -0.4333 | |
| 195 | L | A | -0.6611 | |
| 196 | E | A | -1.7313 | |
| 197 | T | A | -1.1079 | |
| 198 | P | A | -0.9788 | |
| 206 | S | A | -0.8094 | |
| 207 | P | A | -1.1575 | |
| 208 | L | A | -0.6105 | |
| 209 | Y | A | 0.0000 | |
| 210 | S | A | -0.4429 | |
| 211 | V | A | -0.7422 | |
| 212 | E | A | -1.7993 | |
| 213 | F | A | -1.1312 | |
| 214 | S | A | -1.7863 | |
| 215 | E | A | -3.1577 | |
| 216 | E | A | -3.1768 | |
| 217 | P | A | -1.9410 | |
| 218 | F | A | 0.0000 | |
| 219 | G | A | 0.0000 | |
| 220 | V | A | 0.0000 | |
| 221 | I | A | -0.3118 | |
| 222 | V | A | 0.0000 | |
| 223 | H | A | -0.6889 | |
| 224 | R | A | 0.0000 | |
| 225 | Q | A | -0.6913 | |
| 226 | L | A | 0.1404 | |
| 227 | D | A | -1.5123 | |
| 228 | G | A | -1.1728 | |
| 229 | R | A | -0.9124 | |
| 230 | V | A | 0.0227 | |
| 231 | L | A | 0.0000 | |
| 232 | L | A | 0.0000 | |
| 233 | N | A | -0.0596 | |
| 234 | T | A | 0.0000 | |
| 235 | T | A | -0.2234 | |
| 236 | V | A | 0.5576 | |
| 237 | A | A | 0.0000 | |
| 238 | P | A | 0.0000 | |
| 239 | L | A | 0.0000 | |
| 240 | F | A | 0.0000 | |
| 241 | F | A | 0.0000 | |
| 242 | A | A | 0.0000 | |
| 243 | D | A | -1.1732 | |
| 244 | Q | A | -0.8586 | |
| 245 | F | A | 0.0000 | |
| 246 | L | A | 0.0000 | |
| 247 | Q | A | 0.0000 | |
| 248 | L | A | 0.0000 | |
| 249 | S | A | 0.0000 | |
| 250 | T | A | 0.0000 | |
| 251 | S | A | 0.1058 | |
| 252 | L | A | 0.0000 | |
| 253 | P | A | -0.3986 | |
| 254 | S | A | -0.6958 | |
| 255 | Q | A | -0.8154 | |
| 256 | Y | A | -0.1959 | |
| 257 | I | A | 0.0000 | |
| 258 | T | A | 0.0000 | |
| 259 | G | A | 0.0000 | |
| 260 | L | A | 0.0000 | |
| 261 | A | A | 0.0000 | |
| 262 | E | A | 0.0000 | |
| 263 | H | A | -0.2208 | |
| 264 | L | A | -0.1412 | |
| 265 | S | A | -0.2336 | |
| 266 | P | A | -0.3096 | |
| 267 | L | A | 0.0000 | |
| 268 | M | A | 0.0316 | |
| 269 | L | A | -0.0346 | |
| 270 | S | A | -0.4470 | |
| 271 | T | A | -0.4729 | |
| 272 | S | A | -0.5888 | |
| 273 | W | A | -0.4580 | |
| 274 | T | A | -0.7872 | |
| 275 | R | A | -1.6569 | |
| 276 | I | A | 0.0000 | |
| 277 | T | A | 0.0000 | |
| 278 | L | A | 0.0000 | |
| 279 | W | A | 0.0000 | |
| 280 | N | A | 0.0000 | |
| 281 | R | A | -0.2055 | |
| 282 | D | A | -0.1089 | |
| 283 | L | A | 0.1398 | |
| 284 | A | A | 0.0673 | |
| 285 | P | A | 0.0000 | |
| 286 | T | A | -0.1548 | |
| 287 | P | A | -0.4727 | |
| 288 | G | A | -0.8168 | |
| 289 | A | A | 0.0000 | |
| 290 | N | A | 0.0000 | |
| 291 | L | A | 0.0000 | |
| 292 | Y | A | 0.0000 | |
| 293 | G | A | 0.0000 | |
| 294 | S | A | 0.0000 | |
| 295 | H | A | 0.0000 | |
| 296 | P | A | 0.0000 | |
| 297 | F | A | 0.0000 | |
| 298 | Y | A | 0.0000 | |
| 299 | L | A | 0.0000 | |
| 300 | A | A | 0.0000 | |
| 301 | L | A | 0.0000 | |
| 302 | E | A | 0.0000 | |
| 303 | D | A | -2.3654 | |
| 304 | G | A | -1.8960 | |
| 305 | G | A | 0.0000 | |
| 306 | S | A | -1.3690 | |
| 307 | A | A | 0.0000 | |
| 308 | H | A | 0.0000 | |
| 309 | G | A | 0.0000 | |
| 310 | V | A | 0.0000 | |
| 311 | F | A | 0.0000 | |
| 312 | L | A | 0.0000 | |
| 313 | L | A | 0.0000 | |
| 314 | N | A | 0.0000 | |
| 315 | S | A | 0.0000 | |
| 316 | N | A | 0.0000 | |
| 317 | A | A | 0.0000 | |
| 318 | M | A | 0.0000 | |
| 319 | D | A | 0.0000 | |
| 320 | V | A | 0.0000 | |
| 321 | V | A | 0.0000 | |
| 322 | L | A | 0.0000 | |
| 323 | Q | A | 0.0000 | |
| 324 | P | A | -0.6397 | |
| 325 | S | A | -0.6740 | |
| 326 | P | A | -0.4676 | |
| 327 | A | A | 0.0000 | |
| 328 | L | A | 0.0000 | |
| 329 | S | A | 0.0000 | |
| 330 | W | A | 0.0000 | |
| 331 | R | A | 0.0000 | |
| 332 | S | A | 0.0000 | |
| 333 | T | A | 0.0000 | |
| 334 | G | A | 0.0000 | |
| 335 | G | A | 0.0000 | |
| 336 | I | A | -0.4743 | |
| 337 | L | A | 0.0000 | |
| 338 | D | A | 0.0000 | |
| 339 | V | A | 0.0000 | |
| 340 | Y | A | 0.0000 | |
| 341 | I | A | 0.0000 | |
| 342 | F | A | 0.0000 | |
| 343 | L | A | 0.0000 | |
| 344 | G | A | 0.0000 | |
| 345 | P | A | -0.7219 | |
| 346 | E | A | -1.8536 | |
| 347 | P | A | 0.0000 | |
| 348 | K | A | -1.1752 | |
| 349 | S | A | -1.0323 | |
| 350 | V | A | 0.0000 | |
| 351 | V | A | 0.0000 | |
| 352 | Q | A | -1.0446 | |
| 353 | Q | A | 0.0000 | |
| 354 | Y | A | 0.0000 | |
| 355 | L | A | 0.0000 | |
| 356 | D | A | -1.2729 | |
| 357 | V | A | 0.0000 | |
| 358 | V | A | 0.0000 | |
| 359 | G | A | -0.7532 | |
| 360 | Y | A | -0.2183 | |
| 361 | P | A | 0.0000 | |
| 362 | F | A | 0.0000 | |
| 363 | M | A | -0.0112 | |
| 364 | P | A | 0.0000 | |
| 365 | P | A | 0.0000 | |
| 366 | Y | A | 0.0000 | |
| 367 | W | A | 0.0000 | |
| 368 | G | A | 0.0000 | |
| 369 | L | A | 0.0000 | |
| 370 | G | A | 0.0000 | |
| 371 | F | A | 0.0000 | |
| 372 | H | A | 0.0000 | |
| 373 | L | A | 0.0000 | |
| 374 | C | A | 0.0000 | |
| 375 | R | A | -0.0789 | |
| 376 | W | A | 0.4379 | |
| 377 | G | A | 0.3559 | |
| 378 | Y | A | 0.0000 | |
| 379 | S | A | -0.3194 | |
| 380 | S | A | -0.9453 | |
| 381 | T | A | 0.0000 | |
| 382 | A | A | -0.0581 | |
| 383 | I | A | 0.2440 | |
| 384 | T | A | 0.0000 | |
| 385 | R | A | -1.2966 | |
| 386 | Q | A | -1.7167 | |
| 387 | V | A | 0.0000 | |
| 388 | V | A | -1.4403 | |
| 389 | E | A | -2.8928 | |
| 390 | N | A | -2.1523 | |
| 391 | M | A | 0.0000 | |
| 392 | T | A | -1.9788 | |
| 393 | R | A | -2.6672 | |
| 394 | A | A | -1.8162 | |
| 395 | H | A | -1.9068 | |
| 396 | F | A | 0.0000 | |
| 397 | P | A | 0.0000 | |
| 398 | L | A | 0.0000 | |
| 399 | D | A | 0.0000 | |
| 400 | V | A | 0.0000 | |
| 401 | Q | A | 0.0000 | |
| 402 | W | A | 0.0000 | |
| 403 | N | A | 0.0000 | |
| 404 | D | A | 0.0000 | |
| 405 | L | A | 0.0000 | |
| 406 | D | A | -0.6414 | |
| 407 | Y | A | 0.0000 | |
| 408 | M | A | 0.0000 | |
| 409 | D | A | -1.7714 | |
| 410 | S | A | -1.1547 | |
| 411 | R | A | -1.5233 | |
| 412 | R | A | -1.0597 | |
| 413 | D | A | 0.0000 | |
| 414 | F | A | 0.0000 | |
| 415 | T | A | -0.9264 | |
| 416 | F | A | 0.0000 | |
| 417 | N | A | -2.6987 | |
| 418 | K | A | -3.7972 | |
| 419 | D | A | -3.5616 | |
| 420 | G | A | -2.0772 | |
| 421 | F | A | 0.0000 | |
| 422 | R | A | -3.7035 | |
| 423 | D | A | -2.2801 | |
| 424 | F | A | 0.0000 | |
| 425 | P | A | -1.5560 | |
| 426 | A | A | -1.4383 | |
| 427 | M | A | 0.0000 | |
| 428 | V | A | 0.0000 | |
| 429 | Q | A | -2.4017 | |
| 430 | E | A | -2.7356 | |
| 431 | L | A | 0.0000 | |
| 432 | H | A | -1.9469 | |
| 433 | Q | A | -2.4072 | |
| 434 | G | A | -1.8224 | |
| 435 | G | A | -1.1836 | |
| 436 | R | A | 0.0000 | |
| 437 | R | A | -0.8323 | |
| 438 | Y | A | 0.0000 | |
| 439 | M | A | 0.0000 | |
| 440 | M | A | 0.0000 | |
| 441 | I | A | 0.0000 | |
| 442 | V | A | 0.0000 | |
| 443 | D | A | 0.0000 | |
| 444 | P | A | 0.0000 | |
| 445 | A | A | 0.0000 | |
| 446 | I | A | 0.0000 | |
| 447 | S | A | 0.0000 | |
| 448 | S | A | -0.1868 | |
| 449 | S | A | -0.3869 | |
| 450 | G | A | -0.7163 | |
| 451 | P | A | -0.6245 | |
| 452 | A | A | -0.6775 | |
| 453 | G | A | -0.9985 | |
| 454 | S | A | -0.9166 | |
| 455 | Y | A | 0.0000 | |
| 456 | R | A | -1.3428 | |
| 457 | P | A | 0.0000 | |
| 458 | Y | A | -0.6702 | |
| 459 | D | A | -1.2584 | |
| 460 | E | A | 0.0000 | |
| 461 | G | A | 0.0000 | |
| 462 | L | A | -0.7754 | |
| 463 | R | A | -1.9547 | |
| 464 | R | A | -1.5144 | |
| 465 | G | A | -1.1994 | |
| 466 | V | A | 0.0000 | |
| 467 | F | A | 0.0000 | |
| 468 | I | A | 0.0000 | |
| 469 | T | A | -1.3697 | |
| 470 | N | A | -2.2519 | |
| 471 | E | A | -2.5887 | |
| 472 | T | A | -1.6716 | |
| 473 | G | A | -1.9483 | |
| 474 | Q | A | -1.9601 | |
| 475 | P | A | -1.0394 | |
| 476 | L | A | 0.0000 | |
| 477 | I | A | -0.7857 | |
| 478 | G | A | 0.0000 | |
| 479 | K | A | -0.3389 | |
| 480 | V | A | 0.0000 | |
| 481 | W | A | 0.0455 | |
| 482 | P | A | -0.6702 | |
| 483 | G | A | -0.3016 | |
| 484 | S | A | -0.5002 | |
| 485 | T | A | 0.0000 | |
| 486 | A | A | 0.0000 | |
| 487 | F | A | 0.0000 | |
| 488 | P | A | 0.0000 | |
| 489 | D | A | 0.0000 | |
| 490 | F | A | 0.0000 | |
| 491 | T | A | 0.6923 | |
| 492 | N | A | 0.5583 | |
| 493 | P | A | 0.0175 | |
| 494 | T | A | -0.1491 | |
| 495 | A | A | 0.0000 | |
| 496 | L | A | -0.1932 | |
| 497 | A | A | -0.4893 | |
| 498 | W | A | 0.0000 | |
| 499 | W | A | 0.0000 | |
| 500 | E | A | 0.0000 | |
| 501 | D | A | -1.5209 | |
| 502 | M | A | 0.0000 | |
| 503 | V | A | 0.0000 | |
| 504 | A | A | -1.6621 | |
| 505 | E | A | -1.8031 | |
| 506 | F | A | 0.0000 | |
| 507 | H | A | -1.7003 | |
| 508 | D | A | -2.5382 | |
| 509 | Q | A | -1.9184 | |
| 510 | V | A | 0.0000 | |
| 511 | P | A | -1.2031 | |
| 512 | F | A | 0.0000 | |
| 513 | D | A | 0.0000 | |
| 514 | G | A | 0.0000 | |
| 515 | M | A | 0.0000 | |
| 516 | W | A | 0.0000 | |
| 517 | I | A | 0.0000 | |
| 518 | D | A | 0.0000 | |
| 519 | M | A | 0.0000 | |
| 520 | N | A | 0.0000 | |
| 521 | E | A | 0.0000 | |
| 522 | P | A | 0.0000 | |
| 523 | S | A | 0.0000 | |
| 524 | N | A | 0.0000 | |
| 525 | F | A | 1.1394 | |
| 526 | I | A | -0.1167 | |
| 527 | R | A | -1.7159 | |
| 528 | G | A | 0.0000 | |
| 529 | S | A | 0.0000 | |
| 530 | E | A | -2.3075 | |
| 531 | D | A | -2.6606 | |
| 532 | G | A | -1.8752 | |
| 533 | C | A | -1.4845 | |
| 534 | P | A | -1.6668 | |
| 535 | N | A | -2.1032 | |
| 536 | N | A | -2.1769 | |
| 537 | E | A | -2.6640 | |
| 538 | L | A | -1.3835 | |
| 539 | E | A | 0.0000 | |
| 540 | N | A | -2.1689 | |
| 541 | P | A | 0.0000 | |
| 542 | P | A | -0.9163 | |
| 543 | Y | A | 0.0000 | |
| 544 | V | A | 0.2761 | |
| 545 | P | A | 0.0000 | |
| 546 | G | A | -0.4415 | |
| 547 | V | A | 0.0000 | |
| 548 | V | A | 0.0628 | |
| 549 | G | A | -0.4450 | |
| 550 | G | A | -0.4122 | |
| 551 | T | A | -0.5521 | |
| 552 | L | A | 0.0000 | |
| 553 | Q | A | 0.0000 | |
| 554 | A | A | -0.4777 | |
| 555 | A | A | -0.0204 | |
| 556 | T | A | 0.0000 | |
| 557 | I | A | 0.0000 | |
| 558 | C | A | 0.0000 | |
| 559 | A | A | 0.0000 | |
| 560 | S | A | -1.1858 | |
| 561 | S | A | 0.0000 | |
| 562 | H | A | -1.0866 | |
| 563 | Q | A | 0.5623 | |
| 564 | F | A | 2.0747 | |
| 565 | L | A | 1.6829 | |
| 566 | S | A | 0.6710 | |
| 567 | T | A | 0.0695 | |
| 568 | H | A | 0.0000 | |
| 569 | Y | A | 0.0000 | |
| 570 | N | A | -0.0792 | |
| 571 | L | A | 0.0000 | |
| 572 | H | A | 0.0000 | |
| 573 | N | A | 0.0000 | |
| 574 | L | A | 0.0000 | |
| 575 | Y | A | 0.0000 | |
| 576 | G | A | 0.0000 | |
| 577 | L | A | 0.2627 | |
| 578 | T | A | 0.2851 | |
| 579 | E | A | 0.0000 | |
| 580 | A | A | 0.0000 | |
| 581 | I | A | 0.2451 | |
| 582 | A | A | 0.0000 | |
| 583 | S | A | 0.0000 | |
| 584 | H | A | -0.6911 | |
| 585 | R | A | -1.3889 | |
| 586 | A | A | 0.0000 | |
| 587 | L | A | 0.0000 | |
| 588 | V | A | -1.1156 | |
| 589 | K | A | -2.2219 | |
| 590 | A | A | -1.7189 | |
| 591 | R | A | -1.1847 | |
| 592 | G | A | -1.0533 | |
| 593 | T | A | -0.8625 | |
| 594 | R | A | 0.0000 | |
| 595 | P | A | 0.0000 | |
| 596 | F | A | 0.0000 | |
| 597 | V | A | 0.0000 | |
| 598 | I | A | 0.0000 | |
| 599 | S | A | 0.0000 | |
| 600 | R | A | 0.0000 | |
| 601 | S | A | 0.0000 | |
| 602 | T | A | 0.0000 | |
| 603 | F | A | 0.0000 | |
| 604 | A | A | 0.0000 | |
| 605 | G | A | 0.0000 | |
| 606 | H | A | 0.0000 | |
| 607 | G | A | 0.0000 | |
| 608 | R | A | -0.4805 | |
| 609 | Y | A | -0.1242 | |
| 610 | A | A | 0.0000 | |
| 611 | G | A | 0.0000 | |
| 612 | H | A | 0.0000 | |
| 613 | W | A | 0.0000 | |
| 614 | T | A | 0.0000 | |
| 615 | G | A | 0.0000 | |
| 616 | D | A | -0.0408 | |
| 617 | V | A | 0.0000 | |
| 618 | W | A | 0.0752 | |
| 619 | S | A | -0.4116 | |
| 620 | S | A | -0.7166 | |
| 621 | W | A | -1.0333 | |
| 622 | E | A | -1.8450 | |
| 623 | Q | A | 0.0000 | |
| 624 | L | A | 0.0000 | |
| 625 | A | A | 0.0000 | |
| 626 | S | A | -0.6427 | |
| 627 | S | A | 0.0000 | |
| 628 | V | A | 0.0000 | |
| 629 | P | A | 0.0000 | |
| 630 | E | A | 0.0000 | |
| 631 | I | A | 0.0000 | |
| 632 | L | A | 0.0000 | |
| 633 | Q | A | 0.0000 | |
| 634 | F | A | 0.0000 | |
| 635 | N | A | 0.0000 | |
| 636 | L | A | 0.0000 | |
| 637 | L | A | 0.0000 | |
| 638 | G | A | 0.0000 | |
| 639 | V | A | 0.0000 | |
| 640 | P | A | 0.0000 | |
| 641 | L | A | 0.0000 | |
| 642 | V | A | 0.0000 | |
| 643 | G | A | 0.0000 | |
| 644 | A | A | 0.0000 | |
| 645 | D | A | 0.0000 | |
| 646 | V | A | 0.0000 | |
| 647 | C | A | 0.0000 | |
| 648 | G | A | 0.0000 | |
| 649 | F | A | 0.0000 | |
| 650 | L | A | 0.2821 | |
| 651 | G | A | -0.2995 | |
| 652 | N | A | -1.0583 | |
| 653 | T | A | 0.0000 | |
| 654 | S | A | -1.0240 | |
| 655 | E | A | -1.3535 | |
| 656 | E | A | -1.2390 | |
| 657 | L | A | 0.0000 | |
| 658 | C | A | 0.0000 | |
| 659 | V | A | 0.0000 | |
| 660 | R | A | 0.0000 | |
| 661 | W | A | 0.0000 | |
| 662 | T | A | 0.0000 | |
| 663 | Q | A | 0.0000 | |
| 664 | L | A | 0.0000 | |
| 665 | G | A | 0.0000 | |
| 666 | A | A | 0.0000 | |
| 667 | F | A | 0.0000 | |
| 668 | Y | A | 0.0000 | |
| 669 | P | A | 0.0000 | |
| 670 | F | A | 0.0000 | |
| 671 | M | A | 0.0000 | |
| 672 | R | A | 0.0000 | |
| 673 | N | A | 0.0000 | |
| 674 | H | A | 0.0000 | |
| 675 | N | A | 0.0000 | |
| 676 | S | A | 0.6840 | |
| 677 | L | A | 1.4491 | |
| 678 | L | A | 1.7898 | |
| 679 | S | A | 0.6969 | |
| 680 | L | A | 0.5201 | |
| 681 | P | A | 0.1549 | |
| 682 | Q | A | 0.0000 | |
| 683 | E | A | 0.0000 | |
| 684 | P | A | 0.0000 | |
| 685 | Y | A | -0.7315 | |
| 686 | S | A | -0.2697 | |
| 687 | F | A | -0.7684 | |
| 688 | S | A | -1.2545 | |
| 689 | E | A | -2.2779 | |
| 690 | P | A | -1.8182 | |
| 691 | A | A | 0.0000 | |
| 692 | Q | A | -2.0011 | |
| 693 | Q | A | -2.5600 | |
| 694 | A | A | 0.0000 | |
| 695 | M | A | 0.0000 | |
| 696 | R | A | -1.4154 | |
| 697 | K | A | -1.9250 | |
| 698 | A | A | 0.0000 | |
| 699 | L | A | 0.0000 | |
| 700 | T | A | -0.6956 | |
| 701 | L | A | -0.2530 | |
| 702 | R | A | 0.0000 | |
| 703 | Y | A | 0.0000 | |
| 704 | A | A | 0.0000 | |
| 705 | L | A | 0.0000 | |
| 706 | L | A | 0.0000 | |
| 707 | P | A | 0.0000 | |
| 708 | H | A | 0.0000 | |
| 709 | L | A | 0.0000 | |
| 710 | Y | A | 0.0000 | |
| 711 | T | A | 0.0000 | |
| 712 | L | A | -0.2334 | |
| 713 | F | A | 0.0000 | |
| 714 | H | A | 0.0000 | |
| 715 | Q | A | -0.1250 | |
| 716 | A | A | 0.0000 | |
| 717 | H | A | -0.0004 | |
| 718 | V | A | 0.6484 | |
| 719 | A | A | -0.0572 | |
| 720 | G | A | 0.0000 | |
| 721 | E | A | -0.4708 | |
| 722 | T | A | 0.0000 | |
| 723 | V | A | 0.0000 | |
| 724 | A | A | 0.0000 | |
| 725 | R | A | 0.0000 | |
| 726 | P | A | 0.0000 | |
| 727 | L | A | 0.0000 | |
| 728 | F | A | 0.0000 | |
| 729 | L | A | 0.0000 | |
| 730 | E | A | -0.8366 | |
| 731 | F | A | -0.6317 | |
| 732 | P | A | -1.5935 | |
| 733 | K | A | -2.4986 | |
| 734 | D | A | -1.2162 | |
| 735 | S | A | -1.2862 | |
| 736 | S | A | -0.8469 | |
| 737 | T | A | 0.0000 | |
| 738 | W | A | 0.0000 | |
| 739 | T | A | -0.0903 | |
| 740 | V | A | -0.1231 | |
| 741 | D | A | -0.4383 | |
| 742 | H | A | -0.6845 | |
| 743 | Q | A | 0.0000 | |
| 744 | L | A | 0.0000 | |
| 745 | L | A | 0.0000 | |
| 746 | W | A | 0.0000 | |
| 747 | G | A | 0.0000 | |
| 748 | E | A | -0.8083 | |
| 749 | A | A | 0.0000 | |
| 750 | L | A | 0.0000 | |
| 751 | L | A | 0.0000 | |
| 752 | I | A | 0.0000 | |
| 753 | T | A | 0.0000 | |
| 754 | P | A | 0.0000 | |
| 755 | V | A | 0.0000 | |
| 756 | L | A | 0.0000 | |
| 757 | Q | A | -1.8923 | |
| 758 | A | A | -1.0479 | |
| 759 | G | A | -1.3477 | |
| 760 | K | A | -1.6977 | |
| 761 | A | A | -1.3639 | |
| 762 | E | A | -1.7013 | |
| 763 | V | A | -0.8249 | |
| 764 | T | A | -0.6176 | |
| 765 | G | A | 0.0000 | |
| 766 | Y | A | 0.0000 | |
| 767 | F | A | 0.0000 | |
| 768 | P | A | 0.0000 | |
| 769 | L | A | 0.3164 | |
| 770 | G | A | -0.3944 | |
| 771 | T | A | 0.0000 | |
| 772 | W | A | 0.0000 | |
| 773 | Y | A | 0.0000 | |
| 774 | D | A | 0.0000 | |
| 775 | L | A | 0.0000 | |
| 776 | Q | A | -1.0305 | |
| 777 | T | A | -0.7814 | |
| 778 | V | A | 0.0000 | |
| 779 | P | A | -0.4612 | |
| 780 | I | A | -0.3269 | |
| 781 | E | A | -1.5894 | |
| 793 | P | A | -0.8330 | |
| 794 | R | A | -1.3880 | |
| 795 | E | A | -1.9226 | |
| 796 | P | A | -1.5655 | |
| 797 | A | A | -0.9477 | |
| 798 | I | A | 0.0000 | |
| 799 | H | A | -1.3821 | |
| 800 | S | A | 0.0000 | |
| 801 | E | A | -1.8193 | |
| 802 | G | A | -1.1287 | |
| 803 | Q | A | -1.5987 | |
| 804 | N | A | -1.7509 | mutated: WN804A |
| 805 | V | A | -0.6003 | |
| 806 | T | A | -0.5450 | |
| 807 | L | A | 0.0000 | |
| 808 | P | A | -0.9357 | |
| 809 | A | A | 0.0000 | |
| 810 | P | A | -0.8554 | |
| 811 | L | A | -0.7106 | |
| 812 | D | A | -1.8288 | |
| 813 | T | A | 0.0000 | |
| 814 | I | A | -0.3051 | |
| 815 | N | A | 0.0000 | |
| 816 | V | A | 0.0000 | |
| 817 | H | A | 0.0000 | |
| 818 | L | A | 0.0000 | |
| 819 | R | A | -0.2971 | |
| 820 | A | A | -0.9405 | |
| 821 | G | A | -1.1254 | |
| 822 | Y | A | -0.9035 | |
| 823 | I | A | 0.0000 | |
| 824 | I | A | 0.0000 | |
| 825 | P | A | 0.0000 | |
| 826 | L | A | 0.0000 | |
| 827 | Q | A | 0.0000 | |
| 828 | G | A | -0.9886 | |
| 829 | P | A | -0.9203 | |
| 830 | G | A | -0.8398 | |
| 831 | L | A | -0.3404 | |
| 832 | T | A | 0.0000 | |
| 833 | T | A | 0.0000 | |
| 834 | T | A | -1.0771 | |
| 835 | E | A | -1.8275 | |
| 836 | S | A | 0.0000 | |
| 837 | R | A | -1.5281 | |
| 838 | Q | A | -2.0471 | |
| 839 | Q | A | -1.5036 | |
| 840 | P | A | -1.0892 | |
| 841 | M | A | 0.0000 | |
| 842 | A | A | -0.3520 | |
| 843 | L | A | 0.0000 | |
| 844 | A | A | 0.0000 | |
| 845 | V | A | 0.0000 | |
| 846 | A | A | 0.0000 | |
| 847 | L | A | 0.0000 | |
| 848 | T | A | -1.6809 | |
| 849 | K | A | -2.1975 | |
| 850 | G | A | -2.2119 | |
| 851 | G | A | -2.4416 | |
| 852 | E | A | -2.8264 | |
| 853 | A | A | 0.0000 | |
| 854 | R | A | -2.1272 | |
| 855 | G | A | 0.0000 | |
| 856 | E | A | -1.0868 | |
| 857 | L | A | 0.0000 | |
| 858 | F | A | 0.0000 | |
| 859 | W | A | 0.0000 | |
| 860 | D | A | 0.0000 | |
| 861 | D | A | -1.5176 | |
| 862 | G | A | 0.0000 | |
| 863 | E | A | -1.3307 | |
| 864 | S | A | -1.0124 | |
| 865 | L | A | -1.2866 | |
| 866 | E | A | -2.7240 | |
| 867 | V | A | 0.0000 | |
| 868 | L | A | -1.3856 | |
| 869 | E | A | -3.0269 | |
| 870 | R | A | -2.9827 | |
| 871 | G | A | -1.5638 | |
| 872 | A | A | -1.2625 | |
| 873 | Y | A | -0.6373 | |
| 874 | T | A | 0.0000 | |
| 875 | Q | A | -0.1237 | |
| 876 | V | A | 0.0000 | |
| 877 | I | A | -0.5253 | |
| 878 | F | A | 0.0000 | |
| 879 | L | A | -1.0056 | |
| 880 | A | A | 0.0000 | |
| 881 | R | A | -3.2172 | |
| 882 | N | A | -2.7024 | |
| 883 | N | A | -1.8751 | |
| 884 | T | A | -0.9451 | |
| 885 | I | A | 0.0000 | |
| 886 | V | A | -0.2182 | |
| 887 | N | A | 0.0000 | |
| 888 | E | A | -1.3641 | |
| 889 | L | A | -0.2679 | |
| 890 | V | A | 0.8186 | |
| 891 | R | A | -0.0324 | |
| 892 | V | A | 0.3214 | |
| 893 | T | A | -0.1224 | |
| 894 | S | A | -0.4274 | |
| 895 | E | A | -0.7475 | |
| 896 | G | A | 0.0000 | |
| 897 | A | A | -0.5098 | |
| 898 | G | A | -1.0196 | |
| 899 | L | A | 0.0000 | |
| 900 | Q | A | -1.2481 | |
| 901 | L | A | 0.0000 | |
| 902 | Q | A | -0.9861 | |
| 903 | K | A | -0.6269 | |
| 904 | V | A | 0.0000 | |
| 905 | T | A | 0.0000 | |
| 906 | V | A | 0.0000 | |
| 907 | L | A | 0.0000 | |
| 908 | G | A | -0.8428 | |
| 909 | V | A | 0.0000 | |
| 910 | A | A | -0.7119 | |
| 911 | T | A | -0.2736 | |
| 912 | A | A | -0.3766 | |
| 913 | P | A | -0.4638 | |
| 914 | Q | A | -1.2302 | |
| 915 | Q | A | -0.5068 | |
| 916 | V | A | 0.0000 | |
| 917 | L | A | 0.7119 | |
| 918 | S | A | 0.2683 | |
| 919 | N | A | -0.6709 | |
| 920 | G | A | 0.0390 | |
| 921 | V | A | 1.1765 | |
| 922 | P | A | 0.3360 | |
| 923 | V | A | 0.1137 | |
| 924 | S | A | -0.2935 | |
| 925 | N | A | -0.9596 | |
| 926 | F | A | -0.0684 | |
| 927 | T | A | -0.0431 | |
| 928 | Y | A | -0.3105 | |
| 929 | S | A | -0.9879 | |
| 930 | P | A | -1.3972 | |
| 931 | D | A | -2.3124 | |
| 932 | T | A | -1.6087 | |
| 933 | K | A | -1.5503 | |
| 934 | V | A | 0.0000 | |
| 935 | L | A | 0.0000 | |
| 936 | D | A | -0.3785 | |
| 937 | I | A | 0.0000 | |
| 938 | C | A | -0.2326 | |
| 939 | V | A | 0.0000 | |
| 940 | S | A | -0.4282 | |
| 941 | L | A | -0.7179 | |
| 942 | L | A | -0.9111 | |
| 943 | M | A | 0.0000 | |
| 944 | G | A | 0.0000 | |
| 945 | E | A | -2.3925 | |
| 946 | Q | A | -2.1600 | |
| 947 | F | A | 0.0000 | |
| 948 | L | A | 0.3475 | |
| 949 | V | A | 0.0000 | |
| 950 | S | A | -0.2177 | |
| 951 | W | A | 0.0000 | |
| 952 | C | A | 0.0110 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine