Project name: bjklhgujklg

Chain sequence(s)	E: KIDEDIRNLILERRSEVYKFPEDFYKLPGIDFTDEEWKAFVNGGIDIEKMGAARVNAMLDQLFDDFELAMIGKAKENYYNDNKLKKEMKFYEYFDEFKREQLKKWLDNYRDDVIGGTGRAYTASGNYIANAYVEVALESSSLGSGSYLLRMRFTDYSKGQEPMPSGRQNRRDWIENNLDKLK; F: KIDEDIRNLILERRSEVYKFPEDFYKLPGIDFTDEEWKAFVNGGIDIEKMGAARVNAMLDQLFDDFELAMIGKAKENYYNDNKLKKEMKFYEYFDEFKREQLKKWLDNYRDDVIGGTGRAYTASGNYIANAYVEVALESSSLGSGSYLLRMRFTDYSKGQEPMPSGRQNRRDWIENNLDKLK
Selected Chain(s)	E,F
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:08:16)
[INFO]       Main:     Simulation completed successfully.                                          (00:08:18)

• Minimal score value: -4.2635
• Maximal score value: 0.8877
• Average score: -1.1539
• Total score value: -420.036

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	K	E	-2.6208
2	I	E	0.0000
3	D	E	-2.5043
4	E	E	-2.9465
5	D	E	-2.0765
6	I	E	0.0000
7	R	E	-1.5879
8	N	E	-1.6007
9	L	E	0.0000
10	I	E	0.0000
11	L	E	0.0000
12	E	E	-1.2680
13	R	E	0.0000
14	R	E	-0.9325
15	S	E	-1.0115
16	E	E	-1.4836
17	V	E	-0.7090
18	Y	E	0.0000
19	K	E	-1.0798
20	F	E	0.6399
21	P	E	-0.6742
22	E	E	-1.5847
23	D	E	-0.8471
24	F	E	0.0000
25	Y	E	0.0000
26	K	E	-2.7593
27	L	E	0.0000
28	P	E	-1.4149
29	G	E	-1.6240
30	I	E	0.0000
31	D	E	-2.9020
32	F	E	0.0000
33	T	E	-2.5217
34	D	E	-3.2875
35	E	E	-3.3121
36	E	E	-2.7203
37	W	E	0.0000
38	K	E	-3.0366
39	A	E	-2.2266
40	F	E	0.0000
41	V	E	-0.9196
42	N	E	-1.7445
43	G	E	-1.7516
44	G	E	-1.3578
45	I	E	-1.3379
46	D	E	-2.4152
47	I	E	0.0000
48	E	E	-2.8846
49	K	E	-2.8543
50	M	E	0.0000
51	G	E	-2.1119
52	A	E	0.0000
53	A	E	-1.6239
54	R	E	-1.7446
55	V	E	0.0000
56	N	E	-1.3581
57	A	E	-1.5013
58	M	E	0.0000
59	L	E	0.0000
60	D	E	-1.8562
61	Q	E	-0.8214
62	L	E	0.0000
63	F	E	0.0000
64	D	E	0.0000
65	D	E	-0.4985
66	F	E	0.0000
67	E	E	0.0000
68	L	E	0.0367
69	A	E	0.0000
70	M	E	0.0000
71	I	E	0.0000
72	G	E	-1.2622
73	K	E	-0.9580
74	A	E	0.0000
75	K	E	0.0000
76	E	E	-2.2091
77	N	E	-1.5430
78	Y	E	0.0000
79	Y	E	-0.8123
80	N	E	-2.1058
81	D	E	-2.6114
82	N	E	-3.4320
83	K	E	-3.7769
84	L	E	-3.2403
85	K	E	-3.7274
86	K	E	-4.2472
87	E	E	-3.8888
88	M	E	-2.6027
89	K	E	-2.7444
90	F	E	0.0000
91	Y	E	-1.1381
92	E	E	-1.6998
93	Y	E	-1.3309
94	F	E	0.0000
95	D	E	-1.3390
96	E	E	-1.8545
97	F	E	-1.4215
98	K	E	0.0000
99	R	E	-2.1311
100	E	E	-2.6656
101	Q	E	0.0000
102	L	E	0.0000
103	K	E	-2.7419
104	K	E	-2.6359
105	W	E	0.0000
106	L	E	0.0000
107	D	E	-3.3425
108	N	E	-2.9260
109	Y	E	-2.3536
110	R	E	-3.1181
111	D	E	-3.0637
112	D	E	-1.9079
113	V	E	0.0000
114	I	E	-1.4135
115	G	E	-1.0807
116	G	E	0.0000
117	T	E	-0.8335
118	G	E	-1.1124
119	R	E	-1.0311
120	A	E	0.0000
121	Y	E	0.8628
122	T	E	-0.0959
123	A	E	-1.0935
124	S	E	-0.8970
125	G	E	-0.7402
126	N	E	-0.7327
127	Y	E	0.4506
128	I	E	0.1381
129	A	E	-0.4863
130	N	E	-1.5018
131	A	E	-0.7368
132	Y	E	-0.8811
133	V	E	0.0000
134	E	E	-0.7210
135	V	E	0.0000
136	A	E	0.0000
137	L	E	0.0000
138	E	E	-1.3662
139	S	E	-0.7464
140	S	E	0.0000
141	S	E	-0.3251
142	L	E	0.0671
143	G	E	-0.3579
144	S	E	-0.4509
145	G	E	-0.6565
146	S	E	-0.3341
147	Y	E	-0.2017
148	L	E	0.0000
149	L	E	-0.0794
150	R	E	-0.4425
151	M	E	0.0000
152	R	E	-0.4695
153	F	E	0.0000
154	T	E	0.0000
155	D	E	-1.0989
156	Y	E	-0.5960
157	S	E	0.0000
158	K	E	-2.2296
159	G	E	-1.8592
160	Q	E	-2.2495
161	E	E	-2.1941
162	P	E	-1.5875
163	M	E	-1.3506
164	P	E	-1.2365
165	S	E	-1.1359
166	G	E	-1.6795
167	R	E	-2.4779
168	Q	E	-3.0336
169	N	E	-2.7464
170	R	E	-2.4053
171	R	E	0.0000
172	D	E	-2.6985
173	W	E	0.0000
174	I	E	0.0000
175	E	E	-1.9475
176	N	E	-2.1879
177	N	E	0.0000
178	L	E	-1.6311
179	D	E	-2.3589
180	K	E	-1.8399
181	L	E	0.0000
182	K	E	-1.4237
1	K	F	-2.7057
2	I	F	0.0000
3	D	F	-2.5169
4	E	F	-2.8681
5	D	F	-1.9748
6	I	F	0.0000
7	R	F	0.0000
8	N	F	-1.3059
9	L	F	0.0000
10	I	F	0.0000
11	L	F	-0.5066
12	E	F	-1.2501
13	R	F	0.0000
14	R	F	-0.7952
15	S	F	-0.7974
16	E	F	-0.9430
17	V	F	-0.5102
18	Y	F	0.0000
19	K	F	-0.9892
20	F	F	0.6639
21	P	F	-0.5557
22	E	F	-1.4072
23	D	F	-0.7751
24	F	F	0.0000
25	Y	F	0.0000
26	K	F	-2.5038
27	L	F	0.0000
28	P	F	-1.3714
29	G	F	-1.6504
30	I	F	0.0000
31	D	F	-2.7940
32	F	F	0.0000
33	T	F	-2.3573
34	D	F	-3.0084
35	E	F	-3.2033
36	E	F	-2.6506
37	W	F	0.0000
38	K	F	-2.9484
39	A	F	-2.1736
40	F	F	0.0000
41	V	F	-0.7505
42	N	F	-1.7003
43	G	F	-1.6982
44	G	F	-1.3501
45	I	F	-1.3328
46	D	F	-2.4684
47	I	F	0.0000
48	E	F	-3.0134
49	K	F	-2.9277
50	M	F	0.0000
51	G	F	-2.0943
52	A	F	0.0000
53	A	F	-1.5489
54	R	F	-1.7612
55	V	F	0.0000
56	N	F	-1.4455
57	A	F	-1.6506
58	M	F	0.0000
59	L	F	0.0000
60	D	F	-2.3073
61	Q	F	-1.0808
62	L	F	0.0000
63	F	F	0.0000
64	D	F	0.0000
65	D	F	-0.4419
66	F	F	0.0000
67	E	F	0.0000
68	L	F	-0.1695
69	A	F	0.0000
70	M	F	0.0000
71	I	F	0.0000
72	G	F	-1.3675
73	K	F	-1.1252
74	A	F	0.0000
75	K	F	-1.5875
76	E	F	-2.5933
77	N	F	-1.8513
78	Y	F	0.0000
79	Y	F	-1.0310
80	N	F	-2.3285
81	D	F	-2.9078
82	N	F	-3.5372
83	K	F	-3.8422
84	L	F	-3.3612
85	K	F	-3.7590
86	K	F	-4.2635
87	E	F	-3.9209
88	M	F	-2.6904
89	K	F	-2.8385
90	F	F	0.0000
91	Y	F	-1.2985
92	E	F	-2.1283
93	Y	F	-1.5756
94	F	F	0.0000
95	D	F	0.0000
96	E	F	-2.1042
97	F	F	-1.5729
98	K	F	0.0000
99	R	F	-2.2307
100	E	F	-2.7496
101	Q	F	0.0000
102	L	F	0.0000
103	K	F	-2.8208
104	K	F	-2.7738
105	W	F	0.0000
106	L	F	0.0000
107	D	F	-3.3873
108	N	F	-2.9671
109	Y	F	-2.3703
110	R	F	-3.1212
111	D	F	-3.0475
112	D	F	-1.8842
113	V	F	0.0000
114	I	F	-1.3778
115	G	F	-1.0819
116	G	F	0.0000
117	T	F	-0.8823
118	G	F	-1.1470
119	R	F	-1.0464
120	A	F	0.0000
121	Y	F	0.8877
122	T	F	-0.0477
123	A	F	-1.0180
124	S	F	-0.8606
125	G	F	-0.7369
126	N	F	-0.7255
127	Y	F	0.4549
128	I	F	0.1312
129	A	F	-0.5375
130	N	F	-1.6492
131	A	F	-0.7358
132	Y	F	-0.8883
133	V	F	0.0000
134	E	F	-0.7471
135	V	F	0.0000
136	A	F	0.0000
137	L	F	0.0000
138	E	F	-1.2858
139	S	F	-0.6974
140	S	F	0.0000
141	S	F	-0.3512
142	L	F	-0.0162
143	G	F	-0.3979
144	S	F	-0.4721
145	G	F	-0.6659
146	S	F	-0.3615
147	Y	F	-0.2080
148	L	F	0.0000
149	L	F	-0.0481
150	R	F	-0.3983
151	M	F	0.0000
152	R	F	-0.5003
153	F	F	0.0000
154	T	F	-0.6704
155	D	F	-1.1315
156	Y	F	-0.6061
157	S	F	0.0000
158	K	F	-2.3640
159	G	F	-1.9114
160	Q	F	-2.2778
161	E	F	-2.2380
162	P	F	-1.6402
163	M	F	-1.3992
164	P	F	-1.2287
165	S	F	-1.1309
166	G	F	-1.6735
167	R	F	-2.4672
168	Q	F	-3.0117
169	N	F	-2.7168
170	R	F	-2.3772
171	R	F	0.0000
172	D	F	-2.6648
173	W	F	0.0000
174	I	F	0.0000
175	E	F	-1.9239
176	N	F	-2.1793
177	N	F	0.0000
178	L	F	-1.6697
179	D	F	-2.3843
180	K	F	-1.8830
181	L	F	0.0000
182	K	F	-1.4931