Project name: 27137c4654b67be

Chain sequence(s)	A: MAELTETSPETPETTEAIRAVEAFLNALQNEDFDTVDAALGDDLVYENVGFSRIRGGRRTATLLRRMQGRVGFEVKIHRIGADGAAVLTERTDALIIGPLRVQFWVCGVFEVDDGRITLWRDYFDVYDMFKGLLRGLVALVVPSLKATL
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:06)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:08)

• Minimal score value: -3.8054
• Maximal score value: 3.1786
• Average score: -0.701
• Total score value: -104.442

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.8079
2	A	A	0.1425
3	E	A	-1.0456
4	L	A	0.2563
5	T	A	-0.8007
6	E	A	-1.8171
7	T	A	-1.3926
8	S	A	-1.7007
9	P	A	-1.7278
10	E	A	-2.7092
11	T	A	-2.2979
12	P	A	-2.1263
13	E	A	-3.8054
14	T	A	0.0000
15	T	A	-2.6456
16	E	A	-3.4934
17	A	A	0.0000
18	I	A	-1.6976
19	R	A	-2.7335
20	A	A	-2.1675
21	V	A	0.0000
22	E	A	-1.1680
23	A	A	-0.9312
24	F	A	0.0000
25	L	A	0.0000
26	N	A	-1.6927
27	A	A	0.0000
28	L	A	0.0000
29	Q	A	-1.7949
30	N	A	-2.4270
31	E	A	-2.6047
32	D	A	-2.7572
33	F	A	-2.3229
34	D	A	-2.4685
35	T	A	-1.5527
36	V	A	0.0000
37	D	A	-2.3479
38	A	A	-1.2725
39	A	A	-1.1477
40	L	A	0.0000
41	G	A	0.0000
42	D	A	-3.7791
43	D	A	-3.3068
44	L	A	0.0000
45	V	A	-1.4376
46	Y	A	-1.0765
47	E	A	0.0000
48	N	A	0.2700
49	V	A	0.5666
50	G	A	0.7700
51	F	A	1.4023
52	S	A	-0.0363
53	R	A	-1.7319
54	I	A	-1.6530
55	R	A	-3.2365
56	G	A	-3.2155
57	G	A	0.0000
58	R	A	-3.7101
59	R	A	-3.4295
60	T	A	0.0000
61	A	A	0.0000
62	T	A	-2.0679
63	L	A	-1.3837
64	L	A	0.0000
65	R	A	-3.5585
66	R	A	-2.9089
67	M	A	-2.0069
68	Q	A	-2.7724
69	G	A	-1.9550
70	R	A	-2.0845
71	V	A	-0.3593
72	G	A	-0.3032
73	F	A	-0.2377
74	E	A	-0.7379
75	V	A	-0.3376
76	K	A	-0.9747
77	I	A	-0.7708
78	H	A	-1.3470
79	R	A	-1.8255
80	I	A	-0.2230
81	G	A	-0.5973
82	A	A	-1.2227
83	D	A	-2.4014
84	G	A	-2.4193
85	A	A	-2.2402
86	A	A	-0.9167
87	V	A	0.0000
88	L	A	0.6967
89	T	A	0.0000
90	E	A	-0.9295
91	R	A	0.0000
92	T	A	0.0000
93	D	A	0.0000
94	A	A	0.0000
95	L	A	0.9597
96	I	A	0.9093
97	I	A	1.0591
98	G	A	-0.0616
99	P	A	0.2383
100	L	A	0.9628
101	R	A	0.0000
102	V	A	0.0000
103	Q	A	-0.0639
104	F	A	0.0000
105	W	A	0.8186
106	V	A	0.0000
107	C	A	0.5834
108	G	A	0.0000
109	V	A	0.5785
110	F	A	0.0000
111	E	A	-1.6858
112	V	A	0.0000
113	D	A	-3.5704
114	D	A	-3.5879
115	G	A	-3.3071
116	R	A	-2.9179
117	I	A	0.0000
118	T	A	-2.2056
119	L	A	-0.9358
120	W	A	0.0000
121	R	A	-0.0748
122	D	A	0.0000
123	Y	A	0.9255
124	F	A	0.7892
125	D	A	0.1201
126	V	A	1.8975
127	Y	A	1.7026
128	D	A	0.6762
129	M	A	1.0924
130	F	A	1.4312
131	K	A	-0.5345
132	G	A	0.2987
133	L	A	0.9411
134	L	A	0.6291
135	R	A	-0.5348
136	G	A	0.0000
137	L	A	1.9200
138	V	A	2.5333
139	A	A	0.0000
140	L	A	2.4104
141	V	A	3.1786
142	V	A	2.1615
143	P	A	0.9819
144	S	A	0.3937
145	L	A	0.5762
146	K	A	-0.4691
147	A	A	-0.6596
148	T	A	-0.0306
149	L	A	0.3594