Chain sequence(s) |
A: MIAGVDQALAATGQASQRAAGASGGVTVGVGVGTEQRNLSVVAPSQFTFSSRSPDFVDETAGQSWCAILGLNQFHFAVTNDGVI
input PDB |
Selected Chain(s) | A |
Distance of aggregation | 10 Å |
FoldX usage | Yes |
Dynamic mode | No |
Automated mutations | No |
Downloads | Download all the data |
Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00) [WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow to prevent this behavior) (00:00:00) [INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00) [INFO] runJob: Creating pdb object from: input.pdb (00:00:00) [INFO] FoldX: Starting FoldX energy minimalization (00:00:00) [INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:00:25) [INFO] Main: Simulation completed successfully. (00:00:26) |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
1 | M | A | 1.9945 | |
2 | I | A | 2.7606 | |
3 | A | A | 0.9952 | |
4 | G | A | 0.3564 | |
5 | V | A | 1.1561 | |
6 | D | A | -1.1342 | |
7 | Q | A | -1.5154 | |
8 | A | A | -0.4624 | |
9 | L | A | -0.3137 | |
10 | A | A | -0.8645 | |
11 | A | A | -0.5364 | |
12 | T | A | -0.6436 | |
13 | G | A | -1.3710 | |
14 | Q | A | -2.2083 | |
15 | A | A | -1.2070 | |
16 | S | A | -1.6385 | |
17 | Q | A | -2.7947 | |
18 | R | A | -2.7418 | |
19 | A | A | -1.6898 | |
20 | A | A | -1.5376 | |
21 | G | A | -1.4817 | |
22 | A | A | -1.0913 | |
23 | S | A | -0.5880 | |
24 | G | A | -0.4968 | |
25 | G | A | -0.0183 | |
26 | V | A | 0.2749 | |
27 | T | A | 0.0288 | |
28 | V | A | 0.0334 | |
29 | G | A | -1.0992 | |
30 | V | A | -0.6424 | |
31 | G | A | -1.4935 | |
32 | V | A | 0.2445 | |
33 | G | A | -0.6724 | |
34 | T | A | -1.1035 | |
35 | E | A | -2.2945 | |
36 | Q | A | -2.9892 | |
37 | R | A | -3.0953 | |
38 | N | A | -2.4829 | |
39 | L | A | -0.6350 | |
40 | S | A | -0.1148 | |
41 | V | A | 0.0000 | |
42 | V | A | 1.3750 | |
43 | A | A | 0.3263 | |
44 | P | A | -0.4789 | |
45 | S | A | -0.5740 | |
46 | Q | A | -0.5964 | |
47 | F | A | 0.0360 | |
48 | T | A | -0.0035 | |
49 | F | A | 0.1155 | |
50 | S | A | -0.6313 | |
51 | S | A | -0.6474 | |
52 | R | A | -1.6249 | |
53 | S | A | -0.4727 | |
54 | P | A | -0.0193 | |
55 | D | A | -0.9865 | |
56 | F | A | -0.2626 | |
57 | V | A | -0.0095 | |
58 | D | A | -2.2233 | |
59 | E | A | -2.4457 | |
60 | T | A | -1.5431 | |
61 | A | A | -1.2832 | |
62 | G | A | -1.5326 | |
63 | Q | A | -1.7265 | |
64 | S | A | -0.8594 | |
65 | W | A | 0.3893 | |
66 | C | A | 1.2939 | |
67 | A | A | 1.2696 | |
68 | I | A | 2.4600 | |
69 | L | A | 2.3697 | |
70 | G | A | 1.3080 | |
71 | L | A | 1.5774 | |
72 | N | A | -0.4493 | |
73 | Q | A | -0.7248 | |
74 | F | A | 0.8648 | |
75 | H | A | -0.1113 | |
76 | F | A | 1.6133 | |
77 | A | A | 1.6282 | |
78 | V | A | 1.5826 | |
79 | T | A | 0.5416 | |
80 | N | A | -1.3473 | |
81 | D | A | -1.6847 | |
82 | G | A | -0.3551 | |
83 | V | A | 1.8088 | |
84 | I | A | 2.5933 |