Project name: 2abc0a85d88a6d2

Chain sequence(s)	A: QVQLQESGPGLVKPSETLSLTCTVSGFSLTSYGVHWIRQPPGKGLEWIGVIYADGSTNYNPSLKSRVTISKDTSKNQVSLKLSSVTAADTAVYYCARAYGNYWYIDVWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVES
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:33)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:34)

• Minimal score value: -2.8863
• Maximal score value: 2.4912
• Average score: -0.525
• Total score value: -114.4469

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.4913
2	V	A	-0.8962
3	Q	A	-1.7770
4	L	A	0.0000
5	Q	A	-1.8515
6	E	A	0.0000
7	S	A	-0.8307
8	G	A	-0.5117
9	P	A	-0.4966
10	G	A	-0.5319
11	L	A	-0.5492
12	V	A	0.0000
13	K	A	-2.1249
14	P	A	-1.4064
15	S	A	-1.2461
16	E	A	-1.5843
17	T	A	-1.1776
18	L	A	0.0000
19	S	A	-0.7811
20	L	A	0.0000
21	T	A	-0.6910
22	C	A	0.0000
23	T	A	-1.2754
24	V	A	0.0000
25	S	A	-1.1738
26	G	A	-1.0205
27	F	A	-0.4145
28	S	A	-0.4704
29	L	A	0.0000
30	T	A	-0.6299
31	S	A	-0.3015
32	Y	A	0.0737
33	G	A	0.1726
34	V	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	I	A	0.0000
38	R	A	-0.1296
39	Q	A	-0.5525
40	P	A	-0.8958
41	P	A	-1.0300
42	G	A	-1.4283
43	K	A	-2.0875
44	G	A	-0.9053
45	L	A	0.5819
46	E	A	-0.0582
47	W	A	0.3574
48	I	A	0.0000
49	G	A	0.0000
50	V	A	0.0000
51	I	A	0.0000
52	Y	A	-0.3875
53	A	A	-0.7437
54	D	A	-1.8056
55	G	A	-1.2217
56	S	A	-0.8820
57	T	A	-0.7290
58	N	A	-0.9314
59	Y	A	-0.6168
60	N	A	-0.7951
61	P	A	-1.1502
62	S	A	-0.9918
63	L	A	0.0000
64	K	A	-2.0730
65	S	A	-1.3245
66	R	A	-1.3052
67	V	A	0.0000
68	T	A	-0.6934
69	I	A	0.0000
70	S	A	-0.7662
71	K	A	-1.2075
72	D	A	-1.6769
73	T	A	-1.3763
74	S	A	-1.4730
75	K	A	-2.3219
76	N	A	-1.6694
77	Q	A	-1.6112
78	V	A	0.0000
79	S	A	-0.7289
80	L	A	0.0000
81	K	A	-1.2484
82	L	A	0.0000
83	S	A	-0.9593
84	S	A	-0.9317
85	V	A	0.0000
86	T	A	-0.5658
87	A	A	-0.2437
88	A	A	0.0471
89	D	A	0.0000
90	T	A	-0.0443
91	A	A	0.0000
92	V	A	0.1305
93	Y	A	0.0000
94	Y	A	-0.0421
95	C	A	0.0000
96	A	A	0.0000
97	R	A	0.0000
98	A	A	0.0000
99	Y	A	1.2778
100	G	A	0.3059
101	N	A	-0.1649
102	Y	A	1.3814
103	W	A	1.8443
104	Y	A	2.1071
105	I	A	1.3722
106	D	A	0.6490
107	V	A	0.4454
108	W	A	0.0166
109	G	A	-0.9248
110	Q	A	-1.5062
111	G	A	-0.7659
112	T	A	-0.5526
113	T	A	-0.2722
114	V	A	0.0000
115	T	A	0.0000
116	V	A	0.0000
117	S	A	-0.7681
118	S	A	-0.9108
119	A	A	-0.5774
120	S	A	-0.7074
121	T	A	-0.7114
122	K	A	-1.5746
123	G	A	-1.6468
124	P	A	-0.8380
125	S	A	-0.3905
126	V	A	0.0000
127	F	A	0.4901
128	P	A	-0.2640
129	L	A	0.3190
130	A	A	-0.3406
131	P	A	-0.5278
132	C	A	0.0679
133	S	A	-0.8402
134	R	A	-2.2441
135	S	A	-1.5337
136	T	A	-1.2000
137	S	A	-1.2710
138	E	A	-2.1036
139	S	A	-1.1781
140	T	A	-0.8233
141	A	A	0.0000
142	A	A	0.1759
143	L	A	0.0000
144	G	A	0.0000
145	C	A	0.0000
146	L	A	0.4314
147	V	A	0.0000
148	K	A	-0.3764
149	D	A	-1.0756
150	Y	A	0.0000
151	F	A	-0.3777
152	P	A	0.0000
153	E	A	-0.5260
154	P	A	-0.6152
155	V	A	-0.3616
156	T	A	-0.4978
157	V	A	-0.1910
158	S	A	-0.4662
159	W	A	0.0000
160	N	A	-0.9184
161	S	A	-0.7592
162	G	A	-0.5896
163	A	A	-0.2229
164	L	A	-0.0402
165	T	A	-0.3063
166	S	A	-0.4229
167	G	A	-0.4862
168	V	A	-0.0008
169	H	A	-0.3756
170	T	A	0.2773
171	F	A	1.1000
172	P	A	0.8077
173	A	A	1.2924
174	V	A	2.4912
175	L	A	1.9573
176	Q	A	0.2684
177	S	A	-0.3153
178	S	A	-0.4630
179	G	A	-0.0936
180	L	A	0.0363
181	Y	A	0.7544
182	S	A	0.0000
183	L	A	0.0000
184	S	A	0.6375
185	S	A	0.0000
186	V	A	0.5182
187	V	A	0.0000
188	T	A	-0.1918
189	V	A	0.0000
190	P	A	-0.5844
191	S	A	-0.9234
192	S	A	-0.7041
193	S	A	-0.5930
194	L	A	-1.0400
195	G	A	-1.0131
196	T	A	-0.8050
197	K	A	-1.4607
198	T	A	-1.4128
199	Y	A	0.0000
200	T	A	0.0000
201	C	A	0.0000
202	N	A	-1.7245
203	V	A	0.0000
204	D	A	-1.8245
205	H	A	0.0000
206	K	A	-2.6525
207	P	A	-1.5712
208	S	A	-1.8349
209	N	A	-2.6018
210	T	A	-2.0702
211	K	A	-2.6601
212	V	A	-1.7082
213	D	A	-2.7880
214	K	A	-2.5050
215	R	A	-2.8863
216	V	A	0.0000
217	E	A	-2.7817
218	S	A	-1.5399