Project name: 2b0c31dad1b9b6

Chain sequence(s)	C: EVQLVESGGGLVQPGGSLRLSCAASKSVSTMGWFRQAPGKGRELVAAIGGGTSTKGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAREGSGRFKYWGQGTQVTVSS
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:00)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:00)

• Minimal score value: -2.9358
• Maximal score value: 0.9985
• Average score: -0.985
• Total score value: -106.3851

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	C	-2.5887
2	V	C	0.0000
3	Q	C	-1.6933
4	L	C	0.0000
5	V	C	0.9985
6	E	C	0.0696
7	S	C	-0.6800
8	G	C	-0.9935
9	G	C	-0.8191
10	G	C	0.1236
11	L	C	0.8997
12	V	C	0.0000
13	Q	C	-1.4145
14	P	C	-1.5810
15	G	C	-1.4255
16	G	C	-0.9830
17	S	C	-1.3671
18	L	C	-0.9776
19	R	C	-2.1840
20	L	C	0.0000
21	S	C	-0.4413
22	C	C	0.0000
23	A	C	-0.5217
24	A	C	0.0000
25	S	C	-1.7614
26	K	C	-2.7616
27	S	C	-2.0824
28	V	C	0.0000
29	S	C	-1.3457
30	T	C	-1.0489
31	M	C	0.0000
32	G	C	0.0000
33	W	C	0.0000
34	F	C	-0.0919
35	R	C	-1.0899
36	Q	C	-1.8403
37	A	C	-1.8283
38	P	C	-1.1089
39	G	C	-1.7003
40	K	C	-2.8364
41	G	C	-2.5112
42	R	C	-2.3649
43	E	C	-1.7941
44	L	C	0.3878
45	V	C	0.0780
46	A	C	0.0000
47	A	C	-0.0512
48	I	C	0.0000
49	G	C	-1.0982
50	G	C	-1.3438
51	G	C	-1.1593
52	T	C	-0.6148
53	S	C	-0.7434
54	T	C	-1.0913
55	K	C	-1.7848
56	G	C	-1.5247
57	R	C	-1.4748
58	F	C	0.0000
59	T	C	-1.1246
60	I	C	0.0000
61	S	C	-0.7324
62	R	C	-1.5118
63	D	C	-2.0662
64	N	C	-2.7100
65	A	C	-1.8983
66	K	C	-2.9358
67	R	C	-2.9314
68	M	C	-1.5063
69	V	C	0.0000
70	Y	C	-0.6093
71	L	C	0.0000
72	Q	C	-1.5195
73	M	C	0.0000
74	N	C	-1.5651
75	S	C	-1.3115
76	L	C	0.0000
77	R	C	-2.2869
78	A	C	-1.7358
79	E	C	-2.2223
80	D	C	0.0000
81	T	C	-0.9135
82	A	C	0.0000
83	V	C	-0.5967
84	Y	C	0.0000
85	Y	C	-0.2303
86	C	C	0.0000
87	A	C	0.0000
88	A	C	0.0000
89	R	C	-2.3558
90	E	C	-2.8006
91	G	C	-1.7773
92	S	C	-1.4724
93	G	C	-2.0280
94	R	C	-2.8250
95	F	C	-2.0768
96	K	C	-2.7247
97	Y	C	0.0000
98	W	C	-0.3279
99	G	C	-0.2539
100	Q	C	-0.9394
101	G	C	-0.6150
102	T	C	-0.8056
103	Q	C	-1.0538
104	V	C	0.0000
105	T	C	-0.3598
106	V	C	0.0000
107	S	C	-0.8037
108	S	C	-0.5921