Project name: 2bdc74cab07f7f4

Chain sequence(s)	H: QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVSFLWYDGTNKNYVESVKGRFTISRDNSKNMLYLEMNSLRAEDTAVYYCARDHDFRSGYEGWFDPWGQGTLVTVSS; L: EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQHRSNWPPTFGGGTKVEIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:48)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:50)

• Minimal score value: -2.7564
• Maximal score value: 1.9308
• Average score: -0.5247
• Total score value: -120.692

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-0.9458
2	V	H	0.0367
3	Q	H	-0.5091
4	L	H	0.0000
5	V	H	0.4159
6	E	H	0.0000
7	S	H	-0.2031
8	G	H	-0.5105
9	G	H	0.3562
11	G	H	1.0143
12	V	H	1.9308
13	V	H	0.1755
14	Q	H	-1.0699
15	P	H	-1.9707
16	G	H	-2.0819
17	R	H	-2.6540
18	S	H	-1.7833
19	L	H	-0.8703
20	R	H	-1.3051
21	L	H	0.0000
22	S	H	-0.2505
23	C	H	0.0000
24	A	H	-0.2388
25	A	H	0.0000
26	S	H	-0.4026
27	G	H	-0.4336
28	F	H	-0.0148
29	T	H	-0.1009
30	F	H	0.0000
35	S	H	-0.4206
36	S	H	0.0853
37	Y	H	0.4394
38	G	H	0.0000
39	M	H	0.0000
40	H	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	0.0000
44	Q	H	-0.6105
45	A	H	-1.0157
46	P	H	-0.9543
47	G	H	-1.4577
48	K	H	-2.2682
49	G	H	-1.3737
50	L	H	0.0000
51	E	H	-0.8150
52	W	H	0.0000
53	V	H	0.0000
54	S	H	0.0000
55	F	H	0.0000
56	L	H	0.0000
57	W	H	0.1238
58	Y	H	0.6546
59	D	H	-0.3910
62	G	H	-0.5836
63	T	H	-0.5770
64	N	H	-1.0171
65	K	H	-1.5032
66	N	H	-1.1725
67	Y	H	-1.2506
68	V	H	-1.4421
69	E	H	-2.4157
70	S	H	-1.8887
71	V	H	0.0000
72	K	H	-2.6125
74	G	H	-1.7435
75	R	H	-1.6376
76	F	H	0.0000
77	T	H	-0.9979
78	I	H	0.0000
79	S	H	-0.4179
80	R	H	0.0000
81	D	H	-1.4378
82	N	H	-1.6266
83	S	H	-1.5636
84	K	H	-2.3747
85	N	H	-1.8095
86	M	H	-0.9040
87	L	H	0.0000
88	Y	H	-0.2450
89	L	H	0.0000
90	E	H	-0.9073
91	M	H	0.0000
92	N	H	-1.9761
93	S	H	-1.8100
94	L	H	0.0000
95	R	H	-2.3675
96	A	H	-1.5222
97	E	H	-2.1908
98	D	H	0.0000
99	T	H	-0.2483
100	A	H	0.0000
101	V	H	0.8166
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	R	H	-0.3546
107	D	H	0.0000
108	H	H	-0.0243
109	D	H	0.2738
110	F	H	1.0341
111	R	H	-0.5818
111A	S	H	-0.5639
112B	G	H	-0.3238
112A	Y	H	0.3525
112	E	H	0.0000
113	G	H	0.0000
114	W	H	0.0000
115	F	H	0.0000
116	D	H	-0.6098
117	P	H	-0.4345
118	W	H	0.0000
119	G	H	0.0000
120	Q	H	-1.1615
121	G	H	-0.1771
122	T	H	0.0000
123	L	H	1.6988
124	V	H	0.0000
125	T	H	0.6251
126	V	H	-0.4153
127	S	H	-0.0622
128	S	H	-0.1784
1	E	L	-1.4873
2	I	L	0.0000
3	V	L	0.9210
4	L	L	0.0000
5	T	L	-0.3308
6	Q	L	-0.4619
7	S	L	-0.5724
8	P	L	-0.3797
9	A	L	-0.3453
10	T	L	-0.4051
11	L	L	-0.1005
12	S	L	-0.2062
13	L	L	-0.4941
14	S	L	-0.9669
15	P	L	-1.4173
16	G	L	-1.8754
17	E	L	-2.1421
18	R	L	-2.6359
19	A	L	0.0000
20	T	L	-0.6366
21	L	L	0.0000
22	S	L	-0.5789
23	C	L	0.0000
24	R	L	-1.4484
25	A	L	0.0000
26	S	L	-0.4666
27	Q	L	-0.9436
28	S	L	-0.9345
29	V	L	0.0000
36	S	L	-0.5640
37	S	L	-0.4267
38	Y	L	-0.1165
39	L	L	0.0000
40	A	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	-0.7756
45	K	L	-1.1614
46	P	L	-0.8391
47	G	L	-1.3564
48	Q	L	-1.9753
49	A	L	-1.3574
50	P	L	0.0000
51	R	L	-1.2523
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	-0.5413
56	D	L	-0.6441
57	A	L	0.0000
65	S	L	-0.9941
66	N	L	-1.4872
67	R	L	-1.4785
68	A	L	0.0000
69	T	L	-0.6406
70	G	L	-0.6309
71	I	L	0.0000
72	P	L	-0.5423
74	A	L	-0.3522
75	R	L	-0.9461
76	F	L	0.0000
77	S	L	-0.7100
78	G	L	-0.7309
79	S	L	-0.6883
80	G	L	-0.8452
83	S	L	-0.8731
84	G	L	-0.8734
85	T	L	-1.2145
86	D	L	-1.5431
87	F	L	0.0000
88	T	L	-0.5799
89	L	L	0.0000
90	T	L	-0.6300
91	I	L	0.0000
92	S	L	-1.4707
93	S	L	-1.9372
94	L	L	0.0000
95	E	L	-2.7564
96	P	L	-1.7295
97	E	L	-2.3615
98	D	L	0.0000
99	F	L	-0.4318
100	A	L	0.0000
101	V	L	0.0177
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	H	L	0.0000
107	R	L	-0.3283
108	S	L	-0.4906
109	N	L	-1.0273
114	W	L	-0.4564
115	P	L	-0.8399
116	P	L	0.0000
117	T	L	-0.3894
118	F	L	0.0000
119	G	L	0.0000
120	G	L	-0.6474
121	G	L	-0.7520
122	T	L	0.0000
123	K	L	-0.8291
124	V	L	0.0000
125	E	L	0.1313
126	I	L	0.9295
127	K	L	-0.8954