Project name: 2c579cdf4c75e2a

Chain sequence(s)	H: QVKLQQSGAELVGSGASVKLSCTTSGFNIKDFYMHWVKQRPEQGLEWIGWIDPENGDSDYAPKFQGKATMTADSSSNTAYLQLSSLTSEDTAVYYCNAYYGDYEGYWGQGTTVTVSS; L: DIELTQSPAIMSASPGEKVTITCSASSSVSYMHWFQQKPGTSPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISRMEAEDAATYYCQQRSSYPFTFGSGTKLEIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:39)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:41)

• Minimal score value: -3.5674
• Maximal score value: 1.5274
• Average score: -0.5812
• Total score value: -129.6065

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5546
2	V	H	-1.3703
3	K	H	-1.8230
4	L	H	0.0000
5	Q	H	-1.4520
6	Q	H	-1.0232
7	S	H	-0.8585
8	G	H	-0.8465
9	A	H	0.0203
11	E	H	0.2181
12	L	H	1.3672
13	V	H	0.5886
14	G	H	-0.2388
15	S	H	-0.5435
16	G	H	-0.7964
17	A	H	-0.4463
18	S	H	-0.7011
19	V	H	-0.5001
20	K	H	-1.2895
21	L	H	0.0000
22	S	H	-0.4733
23	C	H	0.0000
24	T	H	-0.6578
25	T	H	0.0000
26	S	H	-1.2590
27	G	H	-1.2992
28	F	H	-1.3638
29	N	H	-2.1204
30	I	H	0.0000
35	K	H	-3.3120
36	D	H	-1.8602
37	F	H	-0.4587
38	Y	H	0.3942
39	M	H	0.0000
40	H	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	K	H	0.0000
44	Q	H	-1.0163
45	R	H	-1.6373
46	P	H	-1.5623
47	E	H	-2.4732
48	Q	H	-2.1547
49	G	H	-1.3791
50	L	H	0.0000
51	E	H	-1.3961
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	W	H	-0.1168
56	I	H	0.0000
57	D	H	0.0000
58	P	H	0.0000
59	E	H	-3.5674
62	N	H	-3.1362
63	G	H	-2.6906
64	D	H	-2.7755
65	S	H	-1.2798
66	D	H	-0.8182
67	Y	H	-0.6506
68	A	H	0.0000
69	P	H	-1.6911
70	K	H	-2.3445
71	F	H	0.0000
72	Q	H	-2.0813
74	G	H	-1.4591
75	K	H	-1.3665
76	A	H	0.0000
77	T	H	-0.7340
78	M	H	0.0000
79	T	H	-0.5854
80	A	H	-0.9695
81	D	H	-1.1949
82	S	H	-1.6028
83	S	H	-0.9099
84	S	H	-0.7049
85	N	H	-1.1664
86	T	H	0.0000
87	A	H	0.0000
88	Y	H	-0.2387
89	L	H	0.0000
90	Q	H	-1.0474
91	L	H	0.0000
92	S	H	-0.7643
93	S	H	-0.6575
94	L	H	0.0000
95	T	H	-1.0329
96	S	H	-1.2306
97	E	H	-1.9624
98	D	H	0.0000
99	T	H	-0.5778
100	A	H	0.0000
101	V	H	0.0144
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	N	H	0.0000
106	A	H	0.0000
107	Y	H	0.7068
108	Y	H	0.8556
109	G	H	-0.5603
113	D	H	-1.2912
114	Y	H	0.2400
115	E	H	-0.3242
116	G	H	0.0808
117	Y	H	-0.1072
118	W	H	-0.5724
119	G	H	0.0000
120	Q	H	-1.6000
121	G	H	-0.7835
122	T	H	0.0000
123	T	H	-0.0349
124	V	H	0.0000
125	T	H	0.2023
126	V	H	0.0000
127	S	H	-0.0738
128	S	H	-0.2090
1	D	L	-2.0359
2	I	L	-1.5961
3	E	L	-2.3216
4	L	L	0.0000
5	T	L	-0.6844
6	Q	L	0.0000
7	S	L	0.0158
8	P	L	0.3807
9	A	L	0.6915
10	I	L	1.5274
11	M	L	0.5167
12	S	L	-0.4900
13	A	L	0.0000
14	S	L	-1.8384
15	P	L	-2.0707
16	G	L	-2.3475
17	E	L	-2.8487
18	K	L	-2.9822
19	V	L	0.0000
20	T	L	-0.5786
21	I	L	0.0000
22	T	L	-0.2351
23	C	L	0.0000
24	S	L	-0.6777
25	A	L	0.0000
26	S	L	-1.1973
27	S	L	-0.9236
28	S	L	-0.3775
29	V	L	0.0000
37	S	L	0.1404
38	Y	L	0.9289
39	M	L	0.0000
40	H	L	0.1588
41	W	L	0.0000
42	F	L	0.0000
43	Q	L	0.0000
44	Q	L	-0.8062
45	K	L	-1.0283
46	P	L	-0.6907
47	G	L	-0.8807
48	T	L	-0.9175
49	S	L	-0.7962
50	P	L	0.0000
51	K	L	-1.0945
52	L	L	-0.3589
53	W	L	0.0000
54	I	L	0.0000
55	Y	L	-0.0557
56	S	L	0.1953
57	T	L	0.0300
65	S	L	-0.3864
66	N	L	-0.8482
67	L	L	0.0743
68	A	L	-0.3140
69	S	L	-0.2947
70	G	L	-0.3661
71	V	L	0.0000
72	P	L	-0.1683
74	A	L	-0.0961
75	R	L	-1.0527
76	F	L	0.0000
77	S	L	-0.3834
78	G	L	-0.4176
79	S	L	-0.4074
80	G	L	-0.4487
83	S	L	-0.3686
84	G	L	-0.3989
85	T	L	-0.4072
86	S	L	-0.5554
87	Y	L	0.0000
88	S	L	-0.3243
89	L	L	0.0000
90	T	L	-0.7519
91	I	L	0.0000
92	S	L	-2.0739
93	R	L	-3.3648
94	M	L	0.0000
95	E	L	-2.2391
96	A	L	-1.4422
97	E	L	-1.6933
98	D	L	0.0000
99	A	L	-1.2082
100	A	L	0.0000
101	T	L	-0.4686
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	Q	L	0.0000
107	R	L	0.0665
108	S	L	0.1220
109	S	L	-0.0805
114	Y	L	0.4738
115	P	L	-0.1533
116	F	L	-0.1886
117	T	L	-0.7840
118	F	L	0.0000
119	G	L	0.0000
120	S	L	-0.8783
121	G	L	0.0000
122	T	L	0.0000
123	K	L	-0.4026
124	L	L	0.0000
125	E	L	-1.0204
126	I	L	-1.2191
127	K	L	-1.7954