Project name: 2efa963c13c4830

Chain sequence(s)	H: SVEESGGRLVAPGTPLTLTCTVSGIDLSTYGMGWVRQAPGKGLEYIGIIDSGSTYYANWAKGRFTISKTSTTVDLKMTSLTTEDTATYFCARDRDPSSSGYYFKMWGPGTLVTVSL; L: ALVMTQTPSSVSAAVGGTVTINCQASQSIGSYLAWYQQKPGQPPRLLIYGASNLESGVPSRFKGSGSGTEFTLTISDLECDDAATYYCQTAFYIFSSDNAFGGGTEVVVK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:41)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:42)

• Minimal score value: -2.4786
• Maximal score value: 2.9083
• Average score: -0.4103
• Total score value: -92.7208

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
3	S	H	-0.7833
4	V	H	0.0000
5	E	H	-2.0089
6	E	H	0.0000
7	S	H	-0.8308
8	G	H	-0.4742
9	G	H	-0.2442
11	R	H	-0.5817
12	L	H	1.0919
13	V	H	0.0000
14	A	H	0.6593
15	P	H	0.0908
16	G	H	-0.6872
17	T	H	-0.4550
18	P	H	-0.6522
19	L	H	0.0000
20	T	H	-0.8245
21	L	H	0.0000
22	T	H	-0.8847
23	C	H	0.0000
24	T	H	-0.8409
25	V	H	0.0000
26	S	H	-1.1128
27	G	H	-0.9478
28	I	H	-1.1025
29	D	H	-1.9251
30	L	H	0.0000
35	S	H	-1.1201
36	T	H	-0.9869
37	Y	H	-0.9403
38	G	H	-0.7286
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	0.0000
44	Q	H	-0.7826
45	A	H	-1.1395
46	P	H	-0.9292
47	G	H	-1.5252
48	K	H	-2.2738
49	G	H	-1.4083
50	L	H	0.0000
51	E	H	-0.9119
52	Y	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	I	H	0.1314
56	I	H	0.0000
57	D	H	-1.2825
58	S	H	-1.1092
63	G	H	-1.0253
64	S	H	-0.6374
65	T	H	-0.1384
66	Y	H	0.8863
67	Y	H	0.0656
68	A	H	0.0000
69	N	H	-1.2225
70	W	H	-0.6567
71	A	H	0.0000
72	K	H	-2.1503
74	G	H	-1.6195
75	R	H	-1.3731
76	F	H	0.0000
77	T	H	-0.8277
78	I	H	0.0000
79	S	H	-0.8613
80	K	H	-1.0717
81	T	H	-0.5852
84	S	H	-0.7520
85	T	H	-0.7675
86	T	H	-0.6914
87	V	H	0.0000
88	D	H	-1.0123
89	L	H	0.0000
90	K	H	-1.4661
91	M	H	0.0000
92	T	H	-0.8328
93	S	H	-0.6232
94	L	H	0.0000
95	T	H	-0.8744
96	T	H	-0.9094
97	E	H	-1.8771
98	D	H	0.0000
99	T	H	-0.2667
100	A	H	0.0000
101	T	H	0.4353
102	Y	H	0.0000
103	F	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	R	H	-0.4602
107	D	H	0.0000
108	R	H	-1.4199
109	D	H	-1.3829
110	P	H	-0.9064
111	S	H	-0.6799
111A	S	H	-0.2919
112A	S	H	0.0605
112	G	H	0.0000
113	Y	H	0.6109
114	Y	H	0.0000
115	F	H	0.0000
116	K	H	-1.1174
117	M	H	-0.6039
118	W	H	-0.6544
119	G	H	0.0000
120	P	H	-0.8586
121	G	H	-0.4544
122	T	H	-0.0017
123	L	H	1.1639
124	V	H	0.0000
125	T	H	0.3948
126	V	H	0.0000
127	S	H	0.6982
128	L	H	1.6778
1	A	L	0.3099
2	L	L	0.7323
3	V	L	1.3939
4	M	L	0.0000
5	T	L	-0.3388
6	Q	L	-0.6916
7	T	L	-0.6666
8	P	L	-0.5482
9	S	L	-0.7156
10	S	L	-0.4535
11	V	L	0.0258
12	S	L	0.0126
13	A	L	-0.0771
14	A	L	-0.1286
15	V	L	0.3285
16	G	L	-0.7874
17	G	L	-0.7612
18	T	L	-0.6873
19	V	L	0.0000
20	T	L	-0.3209
21	I	L	0.0000
22	N	L	-1.0511
23	C	L	0.0000
24	Q	L	-1.5251
25	A	L	-0.7746
26	S	L	-0.4607
27	Q	L	-1.3208
28	S	L	-1.1056
29	I	L	0.0000
36	G	L	-0.5214
37	S	L	-0.1525
38	Y	L	0.6004
39	L	L	0.0000
40	A	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	0.0000
45	K	L	-1.6081
46	P	L	-1.1372
47	G	L	-1.3353
48	Q	L	-1.9223
49	P	L	-1.2614
50	P	L	0.0000
51	R	L	-1.7587
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	-0.1828
56	G	L	-0.4459
57	A	L	0.0000
65	S	L	-1.2858
66	N	L	-1.5049
67	L	L	-0.7296
68	E	L	-0.5372
69	S	L	-0.5220
70	G	L	-0.5095
71	V	L	-0.3780
72	P	L	-0.5352
74	S	L	-0.9224
75	R	L	-1.4109
76	F	L	0.0000
77	K	L	-2.0571
78	G	L	-1.2854
79	S	L	-1.2627
80	G	L	-1.1894
83	S	L	-1.0297
84	G	L	-1.2066
85	T	L	-1.7109
86	E	L	-2.4786
87	F	L	0.0000
88	T	L	-1.1182
89	L	L	0.0000
90	T	L	-0.9717
91	I	L	0.0000
92	S	L	-1.4618
93	D	L	-1.9908
94	L	L	0.0000
95	E	L	-1.4986
96	C	L	-0.6432
97	D	L	-1.6288
98	D	L	0.0000
99	A	L	-0.7085
100	A	L	0.0000
101	T	L	-0.6695
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	T	L	0.0000
107	A	L	0.0000
108	F	L	2.3083
109	Y	L	2.5980
110	I	L	2.9083
112	F	L	2.7625
113	S	L	0.8356
114	S	L	1.0343
115	D	L	0.5244
116	N	L	0.5334
117	A	L	0.3396
118	F	L	0.1155
119	G	L	0.0000
120	G	L	-0.8408
121	G	L	-0.9530
122	T	L	0.0000
123	E	L	-1.1380
124	V	L	0.0000
125	V	L	0.4758
126	V	L	-0.0933
127	K	L	-0.9467