Project name: 2510-21.pdb

Chain sequence(s)	H: QVQLVESGGGVVQPGGSLRLSCAASGFTFSIYAMGWARQAPGKGLEWVSGIYSDGSTYYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTAVYYCAPGGSTWSPNALDARGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:35)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:35)

• Minimal score value: -2.7087
• Maximal score value: 1.9259
• Average score: -0.4597
• Total score value: -55.161

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.3128
2	V	H	-0.9452
3	Q	H	-1.0895
4	L	H	0.0000
5	V	H	0.6537
6	E	H	0.1443
7	S	H	-0.2838
8	G	H	-0.8374
9	G	H	0.1751
11	G	H	1.0482
12	V	H	1.6970
13	V	H	0.0787
14	Q	H	-1.3206
15	P	H	-1.6964
16	G	H	-1.5276
17	G	H	-1.1119
18	S	H	-1.4322
19	L	H	-0.9239
20	R	H	-1.9505
21	L	H	0.0000
22	S	H	-0.4389
23	C	H	0.0000
24	A	H	-0.3358
25	A	H	0.0000
26	S	H	-0.8450
27	G	H	-0.8731
28	F	H	0.1017
29	T	H	0.5167
30	F	H	0.0000
35	S	H	0.4140
36	I	H	1.9259
37	Y	H	1.1314
38	A	H	0.4485
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	A	H	0.0000
43	R	H	0.0000
44	Q	H	-0.1555
45	A	H	0.0000
46	P	H	-1.0491
47	G	H	-1.0080
48	K	H	-1.1756
49	G	H	-0.4458
50	L	H	0.9116
51	E	H	0.2286
52	W	H	0.6511
53	V	H	0.0000
54	S	H	0.0000
55	G	H	0.5505
56	I	H	0.0000
57	Y	H	0.5714
58	S	H	-0.2077
59	D	H	-1.6080
63	G	H	-1.1780
64	S	H	-0.3661
65	T	H	0.3631
66	Y	H	0.9200
67	Y	H	-0.1611
68	A	H	-0.8920
69	D	H	-2.2011
70	S	H	-1.5520
71	V	H	0.0000
72	K	H	-2.0066
74	G	H	-1.6027
75	R	H	-1.5338
76	F	H	0.0000
77	T	H	-0.7167
78	I	H	0.0000
79	S	H	-0.4428
80	R	H	-1.1467
81	D	H	-1.8679
82	N	H	-2.4652
83	S	H	-1.9741
84	K	H	-2.7087
85	N	H	-2.2604
86	T	H	-1.3015
87	V	H	0.0000
88	Y	H	-0.5477
89	L	H	0.0000
90	Q	H	-1.3708
91	M	H	0.0000
92	N	H	-2.0252
93	S	H	-1.5183
94	L	H	0.0000
95	R	H	-2.3590
96	A	H	-1.6944
97	E	H	-2.2246
98	D	H	0.0000
99	T	H	-0.3612
100	A	H	0.0000
101	V	H	0.9597
102	Y	H	0.0000
103	Y	H	0.2359
104	C	H	0.0000
105	A	H	-0.6325
106	P	H	0.0000
107	G	H	-0.1065
108	G	H	-0.1792
109	S	H	0.1394
110	T	H	0.2862
111	W	H	0.6920
112A	S	H	-0.2108
112	P	H	-0.5621
113	N	H	-1.2936
114	A	H	-0.8374
115	L	H	-0.8197
116	D	H	-1.8976
117	A	H	-1.4984
118	R	H	-1.7471
119	G	H	0.0000
120	Q	H	-1.0300
121	G	H	0.0000
122	T	H	0.5960
123	L	H	1.6524
124	V	H	0.0000
125	T	H	0.5148
126	V	H	0.0000
127	S	H	-0.4366
128	S	H	-0.4645