Project name: 31848b0217f7c62

Chain sequence(s)	A: AEVRALVAELEATRARTDALIAAALPHLPADLRARFQAAYDAGVARADELAALVAAERWDEALALIEQLLADMETTSRPLVAAVVAALRAAGHDALADELEATFARNVELGRQLLAALRA
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:33)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:33)

• Minimal score value: -3.5437
• Maximal score value: 0.0
• Average score: -1.261
• Total score value: -151.3207

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-1.0579
2	E	A	-1.9888
3	V	A	-1.2555
4	R	A	-1.5452
5	A	A	-1.4410
6	L	A	-1.3653
7	V	A	-1.3583
8	A	A	-1.5735
9	E	A	-2.3626
10	L	A	0.0000
11	E	A	-2.3083
12	A	A	-1.6356
13	T	A	0.0000
14	R	A	-1.8515
15	A	A	-1.7710
16	R	A	-2.5839
17	T	A	0.0000
18	D	A	-2.3007
19	A	A	-1.2353
20	L	A	-0.9854
21	I	A	0.0000
22	A	A	-0.3758
23	A	A	-0.1381
24	A	A	0.0000
25	L	A	-0.2738
26	P	A	-0.4770
27	H	A	-0.7708
28	L	A	0.0000
29	P	A	-0.9039
30	A	A	-1.3544
31	D	A	-2.3602
32	L	A	-1.6313
33	R	A	-1.8285
34	A	A	-1.8055
35	R	A	-2.4543
36	F	A	0.0000
37	Q	A	-1.5199
38	A	A	-1.3427
39	A	A	-1.0216
40	Y	A	-1.1591
41	D	A	-1.9059
42	A	A	-0.9772
43	G	A	-1.2196
44	V	A	-1.5406
45	A	A	-1.6790
46	R	A	-2.3074
47	A	A	0.0000
48	D	A	-2.9716
49	E	A	-2.9669
50	L	A	0.0000
51	A	A	-1.6895
52	A	A	-1.5406
53	L	A	0.0000
54	V	A	0.0000
55	A	A	-0.9944
56	A	A	-1.1622
57	E	A	-2.6577
58	R	A	-2.7812
59	W	A	-2.0111
60	D	A	-2.7021
61	E	A	-2.5057
62	A	A	0.0000
63	L	A	-1.3984
64	A	A	-1.1916
65	L	A	-1.4672
66	I	A	0.0000
67	E	A	-2.4125
68	Q	A	-2.1222
69	L	A	0.0000
70	L	A	0.0000
71	A	A	-1.1882
72	D	A	-1.3245
73	M	A	-0.9078
74	E	A	-1.2959
75	T	A	-0.8554
76	T	A	-0.9367
77	S	A	-1.0919
78	R	A	-1.8139
79	P	A	-0.9091
80	L	A	-0.7960
81	V	A	0.0000
82	A	A	-0.5575
83	A	A	-0.1751
84	V	A	0.0000
85	V	A	0.0000
86	A	A	-0.5089
87	A	A	-0.6052
88	L	A	0.0000
89	R	A	-2.0193
90	A	A	-0.8935
91	A	A	-0.9199
92	G	A	-1.4521
93	H	A	-1.8800
94	D	A	-2.9889
95	A	A	-2.0260
96	L	A	-1.9481
97	A	A	0.0000
98	D	A	-3.5437
99	E	A	-3.3565
100	L	A	0.0000
101	E	A	-2.8924
102	A	A	-2.0486
103	T	A	0.0000
104	F	A	-1.4988
105	A	A	-1.7976
106	R	A	-2.6524
107	N	A	0.0000
108	V	A	0.0000
109	E	A	-3.1408
110	L	A	0.0000
111	G	A	0.0000
112	R	A	-3.1410
113	Q	A	-2.3547
114	L	A	0.0000
115	L	A	-1.5050
116	A	A	-1.0973
117	A	A	-1.2268
118	L	A	-1.1665
119	R	A	-1.8259
120	A	A	-0.7375