Project name: 35c8352f0856718

Chain sequence(s)	H: QVQLVQSGAEVKKPGASVKVSCKASGYTFTNYWMHWVRQAPGQGLEWIGEINPINGRSNYAEKFQGRVTLTVDTSSSTAYMELSRLRSDDTAVYYCARGTRAMHYWGQGTLVTVSS; L: DIQMTQSPSSLSASVGDRVTITCRTSENIYNNLAWYQQKPGKSPKLLIYAATNLADGVPSRFSGSGSGTDYTLTISSLQPEDFATYYCQHFWGTPLTFGGGTKVEIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:21)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:24)

• Minimal score value: -3.347
• Maximal score value: 1.1845
• Average score: -0.6168
• Total score value: -137.5388

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5541
2	V	H	-1.0632
3	Q	H	-1.3131
4	L	H	0.0000
5	V	H	0.7102
6	Q	H	0.0000
7	S	H	-0.3390
8	G	H	-0.3127
9	A	H	0.4237
11	E	H	0.1745
12	V	H	1.0752
13	K	H	-0.9114
14	K	H	-2.3357
15	P	H	-2.5661
16	G	H	-2.2853
17	A	H	-1.7700
18	S	H	-1.8078
19	V	H	0.0000
20	K	H	-1.9513
21	V	H	0.0000
22	S	H	-0.4117
23	C	H	0.0000
24	K	H	-0.7281
25	A	H	0.0000
26	S	H	-0.8808
27	G	H	-1.1068
28	Y	H	-0.5985
29	T	H	-0.3934
30	F	H	0.0000
35	T	H	0.0469
36	N	H	-0.6392
37	Y	H	-0.0021
38	W	H	-0.0209
39	M	H	0.0000
40	H	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	0.0000
44	Q	H	-0.4991
45	A	H	-0.9022
46	P	H	-0.9203
47	G	H	-1.2197
48	Q	H	-1.7444
49	G	H	-1.1540
50	L	H	0.0000
51	E	H	-0.8287
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	E	H	0.0000
56	I	H	0.0000
57	N	H	-0.6166
58	P	H	0.0000
59	I	H	0.8035
62	N	H	-1.0733
63	G	H	-1.3463
64	R	H	-2.1760
65	S	H	-1.2669
66	N	H	-0.9032
67	Y	H	-0.9886
68	A	H	0.0000
69	E	H	-3.2939
70	K	H	-2.9913
71	F	H	0.0000
72	Q	H	-2.5732
74	G	H	-1.8128
75	R	H	-1.8300
76	V	H	0.0000
77	T	H	-0.7056
78	L	H	0.0000
79	T	H	-0.3418
80	V	H	-0.0728
81	D	H	-0.6746
82	T	H	-0.2460
83	S	H	-0.4313
84	S	H	-0.5859
85	S	H	-0.6564
86	T	H	0.0000
87	A	H	0.0000
88	Y	H	-0.4324
89	M	H	0.0000
90	E	H	-1.2711
91	L	H	0.0000
92	S	H	-1.8463
93	R	H	-2.8255
94	L	H	0.0000
95	R	H	-3.3470
96	S	H	-2.3256
97	D	H	-2.5365
98	D	H	0.0000
99	T	H	-0.6743
100	A	H	0.0000
101	V	H	0.5887
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	R	H	0.0000
107	G	H	0.0000
108	T	H	-0.8125
109	R	H	-1.5971
114	A	H	0.0000
115	M	H	0.0000
116	H	H	-0.4847
117	Y	H	-0.1630
118	W	H	-0.1485
119	G	H	0.0000
120	Q	H	-1.1752
121	G	H	-0.3622
122	T	H	0.0000
123	L	H	1.1845
124	V	H	0.0000
125	T	H	-0.0270
126	V	H	0.0000
127	S	H	-1.1339
128	S	H	-0.8556
1	D	L	-2.4850
2	I	L	0.0000
3	Q	L	-2.2781
4	M	L	0.0000
5	T	L	-1.4078
6	Q	L	-1.1203
7	S	L	-0.8594
8	P	L	-0.6570
9	S	L	-0.9168
10	S	L	-1.2565
11	L	L	-0.7775
12	S	L	-0.8717
13	A	L	0.0000
14	S	L	-0.0517
15	V	L	0.9449
16	G	L	-0.3205
17	D	L	-1.3407
18	R	L	-2.0609
19	V	L	0.0000
20	T	L	-0.5788
21	I	L	0.0000
22	T	L	-0.8280
23	C	L	0.0000
24	R	L	-2.8348
25	T	L	0.0000
26	S	L	-2.1328
27	E	L	-2.1355
28	N	L	-1.3102
29	I	L	0.0000
36	Y	L	0.8069
37	N	L	0.0465
38	N	L	-0.0201
39	L	L	0.0000
40	A	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	-0.8933
44	Q	L	-1.3873
45	K	L	-1.8900
46	P	L	-1.2977
47	G	L	-1.6829
48	K	L	-2.6118
49	S	L	-1.5993
50	P	L	0.0000
51	K	L	-1.0848
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	0.0997
56	A	L	-0.1689
57	A	L	0.0000
65	T	L	-0.3057
66	N	L	-0.5032
67	L	L	-0.1115
68	A	L	0.0000
69	D	L	-1.9246
70	G	L	-1.1809
71	V	L	-0.5997
72	P	L	-0.4428
74	S	L	-0.3372
75	R	L	-0.7464
76	F	L	0.0000
77	S	L	-0.3076
78	G	L	0.0000
79	S	L	-0.6457
80	G	L	-0.8447
83	S	L	-0.7849
84	G	L	-0.9460
85	T	L	-1.6823
86	D	L	-2.1429
87	Y	L	0.0000
88	T	L	-0.6758
89	L	L	0.0000
90	T	L	0.0000
91	I	L	0.0000
92	S	L	-1.2576
93	S	L	-0.9276
94	L	L	0.0000
95	Q	L	-0.3628
96	P	L	-0.5976
97	E	L	-1.6335
98	D	L	0.0000
99	F	L	-0.6551
100	A	L	0.0000
101	T	L	-1.2314
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	H	L	0.0000
107	F	L	0.0000
108	W	L	0.3373
109	G	L	-0.1491
114	T	L	-0.5524
115	P	L	-0.9947
116	L	L	0.0000
117	T	L	-0.6702
118	F	L	0.0000
119	G	L	0.0000
120	G	L	-1.1816
121	G	L	-1.0344
122	T	L	0.0000
123	K	L	-2.1987
124	V	L	0.0000
125	E	L	-1.2816
126	I	L	0.7258
127	K	L	-0.8723