Project name: 1350

Chain sequence(s)	H: EVQLLESGGGSVQPGGSLRLSCAASGVTYSHYWLGWFRQAPGKEREGVATIYTNDGTTYYADSVKGRFTISLDNSKNTLYLQMSSLTAEDTAVYYCALRPNDGSWFSPLQPYHYNYRGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:39)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:40)

• Minimal score value: -3.4241
• Maximal score value: 1.8702
• Average score: -0.792
• Total score value: -100.5842

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0032
2	V	H	-1.5834
3	Q	H	-1.4817
4	L	H	0.0000
5	L	H	0.6612
6	E	H	0.0000
7	S	H	-0.3796
8	G	H	-0.8697
9	G	H	-0.8682
11	G	H	-0.6960
12	S	H	-0.6914
13	V	H	-0.7441
14	Q	H	-1.5451
15	P	H	-1.2045
16	G	H	-1.0773
17	G	H	-0.9099
18	S	H	-0.8764
19	L	H	-0.8339
20	R	H	-1.3579
21	L	H	0.0000
22	S	H	-0.1114
23	C	H	0.0000
24	A	H	-0.1349
25	A	H	-0.5060
26	S	H	-0.6772
27	G	H	-0.8544
28	V	H	-0.4927
29	T	H	-0.1423
30	Y	H	-0.3696
35	S	H	-1.0895
36	H	H	-1.7785
37	Y	H	0.0000
38	W	H	0.0000
39	L	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.8154
45	A	H	-1.7124
46	P	H	-1.2735
47	G	H	-1.8059
48	K	H	-3.2360
49	E	H	-3.4241
50	R	H	-2.3060
51	E	H	-2.6182
52	G	H	-1.1671
53	V	H	0.0000
54	A	H	0.0000
55	T	H	0.0000
56	I	H	0.0000
57	Y	H	-0.6247
58	T	H	-1.4657
59	N	H	-2.3750
62	D	H	-2.5471
63	G	H	-1.4295
64	T	H	-0.6331
65	T	H	-0.0996
66	Y	H	0.2252
67	Y	H	-0.6443
68	A	H	-1.3770
69	D	H	-2.4347
70	S	H	-1.7789
71	V	H	0.0000
72	K	H	-2.4864
74	G	H	-1.7031
75	R	H	-1.4983
76	F	H	0.0000
77	T	H	-0.7297
78	I	H	0.0000
79	S	H	-0.2392
80	L	H	-0.6185
81	D	H	-1.6056
82	N	H	-2.2945
83	S	H	-1.8973
84	K	H	-2.6172
85	N	H	-2.0483
86	T	H	-1.0564
87	L	H	0.0000
88	Y	H	-0.1331
89	L	H	0.0000
90	Q	H	-0.9948
91	M	H	0.0000
92	S	H	-0.8400
93	S	H	-0.8550
94	L	H	0.0000
95	T	H	-1.1358
96	A	H	-1.1531
97	E	H	-1.8507
98	D	H	0.0000
99	T	H	-0.7029
100	A	H	0.0000
101	V	H	-0.1558
102	Y	H	0.0000
103	Y	H	-0.5582
104	C	H	0.0000
105	A	H	0.0000
106	L	H	0.0000
107	R	H	-1.2377
108	P	H	-1.3373
109	N	H	-2.1382
110	D	H	-2.4957
111	G	H	-1.2565
111A	S	H	-0.0969
111B	W	H	1.4911
111C	F	H	1.8702
112D	S	H	1.1394
112C	P	H	0.0000
112B	L	H	0.3501
112A	Q	H	-0.5410
112	P	H	-0.7454
113	Y	H	0.6934
114	H	H	-0.3451
115	Y	H	0.0000
116	N	H	-1.4839
117	Y	H	-1.4485
118	R	H	-1.9340
119	G	H	-1.0251
120	Q	H	-1.2908
121	G	H	-0.6680
122	T	H	-0.4863
123	Q	H	-0.7936
124	V	H	0.0000
125	T	H	-0.7223
126	V	H	0.0000
127	S	H	-0.9677
128	S	H	-0.7799