Project name: FIX??

Chain sequence(s)	A: IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTKLT
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:31)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:32)

• Minimal score value: -3.3832
• Maximal score value: 0.9803
• Average score: -0.738
• Total score value: -173.4306

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	I	A	0.0000
2	V	A	0.0000
3	G	A	-0.9107
4	G	A	-1.6198
5	E	A	-2.7476
6	N	A	-2.3816
7	A	A	0.0000
8	K	A	-2.3247
9	P	A	-1.2025
10	G	A	-0.9045
11	Q	A	-1.1089
12	F	A	0.0000
13	P	A	-0.1275
14	W	A	0.0735
15	Q	A	0.0000
16	V	A	0.0000
17	L	A	0.0000
18	L	A	0.0000
19	N	A	-1.5312
20	G	A	-1.6410
21	K	A	-1.8051
22	I	A	0.3434
23	D	A	-1.3740
24	A	A	-0.6136
25	F	A	-0.3352
26	C	A	0.0000
27	G	A	0.0000
28	G	A	0.0000
29	S	A	0.0000
30	I	A	0.0000
31	I	A	-0.1474
32	N	A	-0.3328
33	E	A	-0.7718
34	K	A	-1.1421
35	W	A	0.0000
36	V	A	0.0000
37	V	A	0.0000
38	T	A	0.0000
39	A	A	0.0000
40	A	A	0.0000
41	H	A	-0.9206
42	C	A	0.0000
43	I	A	-0.6036
44	E	A	-1.8625
45	P	A	-1.1288
46	G	A	-1.2410
47	V	A	-1.4475
48	K	A	-1.9359
49	I	A	0.0000
50	T	A	-1.3082
51	V	A	0.0000
52	V	A	0.0000
53	A	A	0.0000
54	G	A	0.0000
55	E	A	-0.7590
56	Y	A	-0.8493
57	N	A	-1.0915
58	T	A	-1.4753
59	E	A	-2.7175
60	E	A	-2.8455
61	T	A	-1.6470
62	E	A	-1.3448
63	P	A	-0.7550
64	T	A	-0.7086
65	E	A	-1.0085
66	Q	A	-1.1785
67	R	A	-2.3650
68	R	A	0.0000
69	N	A	-1.3250
70	V	A	-0.2096
71	I	A	0.6745
72	R	A	-0.3784
73	A	A	0.0697
74	I	A	-0.2718
75	P	A	-0.4607
76	H	A	-0.7112
77	H	A	-1.1919
78	S	A	-0.8764
79	Y	A	-0.8616
80	N	A	-0.9343
81	A	A	-0.2188
82	T	A	0.2458
83	V	A	0.9126
84	N	A	-0.4290
85	K	A	-1.6191
86	Y	A	-0.7200
87	S	A	-0.5557
88	H	A	-1.0607
89	D	A	0.0000
90	I	A	0.0000
91	A	A	0.0000
92	L	A	0.0000
93	L	A	0.0000
94	E	A	0.0000
95	L	A	0.0000
96	D	A	-1.4874
97	E	A	-2.5309
98	P	A	-1.5338
99	L	A	0.0000
100	T	A	-0.2083
101	L	A	0.4460
102	N	A	-0.2950
103	S	A	-0.3230
104	Y	A	-0.0729
105	V	A	0.0000
106	T	A	0.0184
107	P	A	0.1230
108	I	A	0.0000
109	C	A	0.1162
110	I	A	-0.3176
111	A	A	-1.1575
112	D	A	-3.0701
113	K	A	-3.2721
114	E	A	-2.6048
115	Y	A	-0.4774
116	T	A	0.0000
117	N	A	-1.2537
118	I	A	0.0323
119	F	A	0.0000
120	L	A	0.0000
121	K	A	-0.8147
122	F	A	0.9803
123	G	A	0.1090
124	S	A	-0.5228
125	G	A	0.0000
126	Y	A	-0.6594
127	V	A	0.0000
128	S	A	0.0000
129	G	A	0.0000
130	W	A	0.0000
131	G	A	0.0000
132	R	A	-1.5591
133	V	A	-0.6821
134	F	A	0.1287
135	N	A	-1.4600
136	R	A	-2.7105
137	G	A	-1.7731
138	R	A	-2.2941
139	S	A	-1.4146
140	A	A	0.0000
141	T	A	-0.8704
142	I	A	-0.6800
143	L	A	0.0000
144	Q	A	0.0000
145	Y	A	-1.2159
146	L	A	0.0000
147	K	A	-1.5976
148	V	A	0.0000
149	P	A	-0.4297
150	L	A	-0.5019
151	V	A	0.0000
152	D	A	-2.2141
153	R	A	-2.4838
154	A	A	-1.5058
155	T	A	-1.5685
156	C	A	0.0000
157	L	A	-1.2557
158	R	A	-2.2312
159	S	A	-1.5699
160	T	A	-1.4109
161	K	A	-1.8431
162	F	A	-0.5817
163	T	A	-0.2563
164	I	A	0.0000
165	Y	A	0.2206
166	S	A	-0.5004
167	N	A	-0.5696
168	M	A	0.0000
169	F	A	0.0000
170	C	A	0.0000
171	A	A	0.0000
172	G	A	0.0000
173	F	A	-1.2854
174	H	A	-2.3224
175	E	A	-3.1611
176	G	A	-2.4067
177	G	A	-1.4739
178	K	A	-1.7316
179	D	A	0.0000
180	S	A	0.0000
181	C	A	-1.2911
182	Q	A	-1.6804
183	G	A	-0.8042
184	D	A	0.0000
185	S	A	-0.2788
186	G	A	0.0000
187	G	A	0.0000
188	P	A	0.0000
189	H	A	0.0000
190	V	A	0.0000
191	T	A	0.0000
192	E	A	-1.9504
193	V	A	-1.3037
194	E	A	-2.3727
195	G	A	-1.7372
196	T	A	-1.1523
197	S	A	0.0000
198	F	A	0.0664
199	L	A	0.0000
200	T	A	0.0000
201	G	A	0.0000
202	I	A	0.0000
203	I	A	0.0000
204	S	A	0.0000
205	W	A	-0.7222
206	G	A	-1.2851
207	E	A	-1.8964
208	E	A	-2.4622
209	C	A	0.0000
210	A	A	-1.3053
211	V	A	-1.6509
212	K	A	-2.8594
213	G	A	-2.1064
214	K	A	-2.1436
215	Y	A	0.0000
216	G	A	0.0000
217	I	A	0.0000
218	Y	A	0.0000
219	T	A	0.0000
220	K	A	-0.7578
221	V	A	0.0000
222	S	A	0.0000
223	R	A	-2.5727
224	Y	A	0.0000
225	V	A	0.0000
226	N	A	-2.6636
227	W	A	0.0000
228	I	A	0.0000
229	K	A	-3.3832
230	E	A	-3.3669
231	K	A	-2.4000
232	T	A	0.0000
233	K	A	-2.0879
234	L	A	0.2619
235	T	A	0.1838