Project name: AAB-PP3136

Chain sequence(s)	H: QVQLVESGGGVVQPGESLKISCAASGFTFSSYAMHWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARSTYYYSGSGYDYYFSPWGPGTLVTVSS; L: DIQMTQSPSSLSASVGDRVTITCRASQHIRSSLAWYQQKPGKAPKLLIYGASSRATGIPDRFSGSGSGTDFTLTISSLQPEDFATYYCQHTYITPYTFGQGTKVEIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	No
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       runJob:   FoldX not utilized. Treating input pdb file as it was already optimized.    (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:00)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:02)

• Minimal score value: -3.1592
• Maximal score value: 2.2876
• Average score: -0.5522
• Total score value: -128.1188

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
0	Q	H	-1.3202
1	V	H	-0.6603
2	Q	H	-0.7863
3	L	H	0.0000
4	V	H	1.4094
5	E	H	0.0000
6	S	H	-0.1168
7	G	H	-0.7689
8	G	H	0.1467
9	G	H	0.9357
10	V	H	1.5578
11	V	H	0.0000
12	Q	H	-1.7854
13	P	H	-1.9044
14	G	H	-2.0580
15	E	H	-2.2305
16	S	H	-1.6169
17	L	H	-1.0046
18	K	H	-1.9370
19	I	H	0.0000
20	S	H	-0.3146
21	C	H	0.0000
22	A	H	0.0337
23	A	H	0.0000
24	S	H	-0.5579
25	G	H	-0.8650
26	F	H	-0.3016
27	T	H	-0.1827
28	F	H	0.0000
29	S	H	-0.8178
30	S	H	-0.0829
31	Y	H	0.2925
32	A	H	0.1588
33	M	H	0.0000
34	H	H	0.0000
35	W	H	0.0000
36	V	H	0.0000
37	R	H	0.0000
38	Q	H	-0.7139
39	A	H	-1.0389
40	P	H	-0.9808
41	G	H	-1.5053
42	K	H	-2.3825
43	G	H	-1.6177
44	L	H	0.0000
45	E	H	-1.2231
46	W	H	0.0000
47	V	H	0.0000
48	S	H	0.0000
49	A	H	0.0000
50	I	H	0.0000
51	S	H	-0.2778
52	G	H	-0.4672
53	S	H	-0.7135
54	G	H	-0.8170
55	G	H	-0.7433
56	S	H	-0.2712
57	T	H	0.2830
58	Y	H	0.6671
59	Y	H	-0.3169
60	A	H	-1.1567
61	D	H	-2.3318
62	S	H	-1.7123
63	V	H	0.0000
64	K	H	-2.4210
65	G	H	-1.6970
66	R	H	-1.2516
67	F	H	0.0000
68	T	H	-0.6642
69	I	H	0.0000
70	S	H	-0.4646
71	R	H	-1.0829
72	D	H	-1.6529
73	N	H	-1.8137
74	S	H	-1.6409
75	K	H	-2.4423
76	N	H	-1.8730
77	T	H	-1.0092
78	L	H	0.0000
79	Y	H	-0.4660
80	L	H	0.0000
81	Q	H	-1.1229
82	M	H	0.0000
83	N	H	-1.7213
84	S	H	-1.6523
85	L	H	0.0000
86	R	H	-2.7468
87	A	H	-1.8985
88	E	H	-2.3049
89	D	H	0.0000
90	T	H	-0.4242
91	A	H	0.0000
92	V	H	0.9036
93	Y	H	0.0000
94	Y	H	0.0000
95	C	H	0.0000
96	A	H	0.0000
97	R	H	-0.2023
98	S	H	0.0000
99	T	H	1.0594
100	Y	H	2.2876
101	Y	H	2.2181
102	Y	H	1.7705
103	S	H	0.2281
104	G	H	-0.4643
105	S	H	-0.2739
106	G	H	0.1692
107	Y	H	1.7943
108	D	H	1.5877
109	Y	H	1.6072
110	Y	H	0.7342
111	F	H	0.0000
112	S	H	-0.2184
113	P	H	-0.4834
114	W	H	-0.3677
115	G	H	0.0000
116	P	H	-0.3505
117	G	H	0.1926
118	T	H	0.7510
119	L	H	1.7415
120	V	H	0.0000
121	T	H	0.3771
122	V	H	0.0000
123	S	H	-0.6586
124	S	H	-0.5988
125	D	L	-2.0071
126	I	L	0.0000
127	Q	L	-2.1936
128	M	L	0.0000
129	T	L	-1.2805
130	Q	L	0.0000
131	S	L	-0.7313
132	P	L	-0.5981
133	S	L	-0.9592
134	S	L	-1.1325
135	L	L	-0.6517
136	S	L	-0.7039
137	A	L	0.0000
138	S	L	-0.1485
139	V	L	0.7188
140	G	L	-0.7067
141	D	L	-1.6686
142	R	L	-2.3428
143	V	L	0.0000
144	T	L	-0.6350
145	I	L	0.0000
146	T	L	-0.9483
147	C	L	0.0000
148	R	L	-3.0416
149	A	L	0.0000
150	S	L	-2.2568
151	Q	L	-2.8593
152	H	L	-2.5706
153	I	L	0.0000
154	R	L	-2.5968
155	S	L	-1.4645
156	S	L	-0.3889
157	L	L	0.0000
158	A	L	0.0000
159	W	L	0.0000
160	Y	L	0.0000
161	Q	L	-1.0061
162	Q	L	0.0000
163	K	L	-2.0262
164	P	L	-1.4698
165	G	L	-1.6564
166	K	L	-2.5542
167	A	L	-1.5274
168	P	L	0.0000
169	K	L	-1.9921
170	L	L	-0.7939
171	L	L	0.0000
172	I	L	0.0000
173	Y	L	-0.1841
174	G	L	-0.8096
175	A	L	0.0000
176	S	L	-0.7904
177	S	L	-0.8352
178	R	L	-1.6610
179	A	L	-0.8894
180	T	L	-0.5883
181	G	L	-0.9209
182	I	L	0.0000
183	P	L	-1.3870
184	D	L	-2.3069
185	R	L	-1.6180
186	F	L	0.0000
187	S	L	-1.0293
188	G	L	-0.5935
189	S	L	-0.8338
190	G	L	-1.4388
191	S	L	-1.8332
192	G	L	-2.4331
193	T	L	-2.6644
194	D	L	-3.1592
195	F	L	0.0000
196	T	L	-0.9090
197	L	L	0.0000
198	T	L	-0.6142
199	I	L	0.0000
200	S	L	-1.6832
201	S	L	-1.2900
202	L	L	0.0000
203	Q	L	-0.7758
204	P	L	-0.6465
205	E	L	-1.8864
206	D	L	0.0000
207	F	L	-0.5659
208	A	L	0.0000
209	T	L	-1.2462
210	Y	L	0.0000
211	Y	L	0.0000
212	C	L	0.0000
213	Q	L	0.0000
214	H	L	0.0000
215	T	L	1.2003
216	Y	L	1.5394
217	I	L	2.0530
218	T	L	0.8456
219	P	L	0.0153
220	Y	L	0.0000
221	T	L	-0.4581
222	F	L	-0.4808
223	G	L	0.0000
224	Q	L	-1.5889
225	G	L	0.0000
226	T	L	0.0000
227	K	L	-2.0579
228	V	L	0.0000
229	E	L	-0.9095
230	I	L	0.9387
231	K	L	-0.7860