Project name: LVAS

Chain sequence(s)	H: EVQLLESGGGLVQPGGSLRLSCAASGYTNRLKCMGWFRQAPGKERELVASISTGTGNTYYADSVKGRFTISRDNSKNTLYLQMNSLKAEDTAVYYCAADVRPDGTTCHYNSRGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:49)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:49)

• Minimal score value: -3.1589
• Maximal score value: 1.8277
• Average score: -0.842
• Total score value: -102.7258

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0241
2	V	H	-1.5696
3	Q	H	-1.5653
4	L	H	0.0000
5	L	H	0.7127
6	E	H	0.0000
7	S	H	-0.1503
8	G	H	-0.6924
9	G	H	0.1869
11	G	H	0.7148
12	L	H	1.4572
13	V	H	-0.0065
14	Q	H	-1.3747
15	P	H	-1.7098
16	G	H	-1.4946
17	G	H	-0.9940
18	S	H	-1.1972
19	L	H	-0.7363
20	R	H	-1.8768
21	L	H	0.0000
22	S	H	-0.3810
23	C	H	0.0000
24	A	H	-0.3208
25	A	H	-0.4891
26	S	H	-0.7690
27	G	H	-1.1050
28	Y	H	-0.9824
29	T	H	-1.1789
30	N	H	-1.9425
35	R	H	-2.0534
36	L	H	-1.1370
37	K	H	-1.8726
38	C	H	-0.9021
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	-0.1873
43	R	H	0.0000
44	Q	H	-1.2135
45	A	H	-1.4167
46	P	H	-1.2839
47	G	H	-1.8878
48	K	H	-3.1396
49	E	H	-3.1589
50	R	H	-1.9225
51	E	H	-1.2496
52	L	H	0.0978
53	V	H	0.0000
54	A	H	0.0000
55	S	H	0.3383
56	I	H	0.0000
57	S	H	-0.9443
58	T	H	-1.3657
59	G	H	-1.0519
62	T	H	-1.0112
63	G	H	-1.1834
64	N	H	-1.2696
65	T	H	-0.0713
66	Y	H	0.7350
67	Y	H	-0.1588
68	A	H	-1.0165
69	D	H	-2.3724
70	S	H	-1.9907
71	V	H	0.0000
72	K	H	-2.4371
74	G	H	-1.7677
75	R	H	-1.7636
76	F	H	0.0000
77	T	H	-0.6496
78	I	H	0.0000
79	S	H	-0.7033
80	R	H	-1.4848
81	D	H	-2.1243
82	N	H	-2.6688
83	S	H	-2.1516
84	K	H	-2.9617
85	N	H	-2.7290
86	T	H	0.0000
87	L	H	0.0000
88	Y	H	-0.5393
89	L	H	0.0000
90	Q	H	-1.1548
91	M	H	0.0000
92	N	H	-1.3907
93	S	H	-1.3390
94	L	H	0.0000
95	K	H	-2.5879
96	A	H	-1.8292
97	E	H	-2.3486
98	D	H	0.0000
99	T	H	-0.3655
100	A	H	0.0000
101	V	H	0.9613
102	Y	H	0.0000
103	Y	H	-0.0465
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	D	H	0.0000
108	V	H	-0.8287
109	R	H	-1.4789
110	P	H	-1.5427
111	D	H	-2.1955
111A	G	H	-1.5040
112A	T	H	-1.1567
112	T	H	-0.7480
113	C	H	-1.0621
114	H	H	-1.3364
115	Y	H	0.0000
116	N	H	-1.7816
117	S	H	-1.8171
118	R	H	-2.2936
119	G	H	-1.2531
120	Q	H	-1.3334
121	G	H	0.0000
122	T	H	0.6892
123	L	H	1.8277
124	V	H	0.0000
125	T	H	0.4126
126	V	H	0.0000
127	S	H	-0.6204
128	S	H	-0.4431