Project name: 3feaaae97f0da0a

Chain sequence(s)	H: EVQLVESGGGVVQPGGSLKLSCVASGTDFSINFIRWYRQAPGKQREFVAGFTATGNTNYADSMKGRFTISRDNTKNAVYLQIDSLKPEDTAVYYCYMLDKWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:14)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:15)

• Minimal score value: -2.9844
• Maximal score value: 1.5345
• Average score: -0.7981
• Total score value: -88.5899

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1364
2	V	H	-1.9092
3	Q	H	-1.0983
4	L	H	0.4377
5	V	H	1.5345
6	E	H	0.4717
7	S	H	-0.3773
9	G	H	-1.1411
10	G	H	-0.6913
11	G	H	0.3192
12	V	H	1.2976
13	V	H	0.0398
14	Q	H	-1.3439
15	P	H	-1.3753
16	G	H	-1.4599
17	G	H	-0.9006
18	S	H	-1.0740
19	L	H	-0.7856
20	K	H	-1.8873
21	L	H	0.0000
22	S	H	-0.1019
23	C	H	0.0000
24	V	H	0.8886
25	A	H	0.0000
26	S	H	-1.0291
27	G	H	-1.6394
29	T	H	-1.6571
30	D	H	-1.9031
31	F	H	0.0000
32	S	H	-0.7881
33	I	H	-0.0645
39	N	H	-0.1923
40	F	H	0.5283
41	I	H	0.0000
42	R	H	-0.0210
43	W	H	0.0000
44	Y	H	-0.3447
45	R	H	0.0000
46	Q	H	-1.6842
47	A	H	-1.6943
48	P	H	-1.1699
49	G	H	-1.6934
50	K	H	-2.9844
51	Q	H	-2.8153
52	R	H	-2.1062
53	E	H	-1.7734
54	F	H	-0.6096
55	V	H	0.0000
56	A	H	0.0000
57	G	H	0.0000
58	F	H	-0.5538
59	T	H	-0.6363
60	A	H	-0.4888
65	T	H	-0.5505
66	G	H	-1.1613
67	N	H	-1.5763
68	T	H	-1.2047
69	N	H	-1.8076
70	Y	H	-1.2919
71	A	H	-1.4982
72	D	H	-2.4977
73	S	H	-1.5903
74	M	H	0.0000
75	K	H	-2.7333
76	G	H	-1.7820
77	R	H	-1.4422
78	F	H	0.0000
79	T	H	-0.8994
80	I	H	0.0000
81	S	H	-0.4902
82	R	H	-1.0225
83	D	H	-1.5617
84	N	H	-2.2975
85	T	H	-1.7435
86	K	H	-2.3244
87	N	H	-1.7742
88	A	H	0.0000
89	V	H	0.0000
90	Y	H	-0.1320
91	L	H	0.0000
92	Q	H	-1.0513
93	I	H	0.0000
94	D	H	-1.5883
95	S	H	-1.3488
96	L	H	0.0000
97	K	H	-2.5121
98	P	H	-2.0442
99	E	H	-2.3865
100	D	H	0.0000
101	T	H	-0.8407
102	A	H	0.0000
103	V	H	-0.2786
104	Y	H	0.0000
105	Y	H	-0.0558
106	C	H	0.0000
107	Y	H	-0.1053
108	M	H	0.0000
109	L	H	-0.3659
137	D	H	-1.8372
138	K	H	-1.5857
139	W	H	-0.3922
140	G	H	-0.1828
141	Q	H	-0.7188
142	G	H	-0.4504
143	T	H	-0.6504
144	Q	H	-0.7186
145	V	H	0.0000
146	T	H	-0.1820
147	V	H	0.0000
148	S	H	-0.7921
149	S	H	-0.5072