| Chain sequence(s) |
A: MTSLFAAIQPYKTHLLRVSPLHRLSIKEYGNPQGKPVVFLHGGPGGGASDSDARRFNPTTYRIVLFDQRGSGESTPASCLEDNTTQALVEDIEKIREFLQVGAAWHVFGGSWGSTLALAYAQAHPARVKSLTLRGIFTLRKKELDFFYQGPGSSFIFPEYWEEYLDPIPVAERGDMVKAYYERLTGSDEKVRAEAGRAWSRWEMATSRLHVDPDYISKADAPGFADAFARIESHYFVNGGFMPEGELLKPENIAKISHIPAVIVQGRYDMVCPITTAYELTKLWPEAKFVVIPDAGHSAIEAGTEKALVEATEEFAKLA
B: MTSLFAAIQPYKTHLLRVSPLHRLSIKEYGNPQGKPVVFLHGGPGGGASDSDARRFNPTTYRIVLFDQRGSGESTPASCLEDNTTQALVEDIEKIREFLQVGAAWHVFGGSWGSTLALAYAQAHPARVKSLTLRGIFTLRKKELDFFYQGPGSSFIFPEYWEEYLDPIPVAERGDMVKAYYERLTGSDEKVRAEAGRAWSRWEMATSRLHVDPDYISKADAPGFADAFARIESHYFVNGGFMPEGELLKPENIAKISHIPAVIVQGRYDMVCPITTAYELTKLWPEAKFVVIPDAGHSAIEAGTEKALVEATEEFAKLA input PDB |
| Selected Chain(s) | A,B |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | FR155B,IK156B,RA267B,EA159B,EA162B,EA159A,EA162A,KA282A,FR155A,KA282B,IK156A,RA267A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 23.6773 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:02)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:02)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:02)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:02)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:02)
[INFO] FoldX: Building mutant model (00:14:22)
[INFO] FoldX: Starting FoldX energy minimalization (00:27:33)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:35:04)
[INFO] Main: Simulation completed successfully. (00:35:12)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | 0.9394 | |
| 2 | T | A | 0.4634 | |
| 3 | S | A | -0.3191 | |
| 4 | L | A | 0.2057 | |
| 5 | F | A | 0.3342 | |
| 6 | A | A | 0.1231 | |
| 7 | A | A | -0.1722 | |
| 8 | I | A | -0.4185 | |
| 9 | Q | A | -1.3754 | |
| 10 | P | A | -0.9967 | |
| 11 | Y | A | -0.5001 | |
| 12 | K | A | -1.4438 | |
| 13 | T | A | -0.5452 | |
| 14 | H | A | -0.0134 | |
| 15 | L | A | 0.6120 | |
| 16 | L | A | -0.2364 | |
| 17 | R | A | -1.8066 | |
| 18 | V | A | 0.0000 | |
| 19 | S | A | -0.8034 | |
| 20 | P | A | -0.4208 | |
| 21 | L | A | -0.4573 | |
| 22 | H | A | 0.0000 | |
| 23 | R | A | -1.3572 | |
| 24 | L | A | 0.0000 | |
| 25 | S | A | 0.0000 | |
| 26 | I | A | 0.0000 | |
| 27 | K | A | -0.9230 | |
| 28 | E | A | 0.0000 | |
| 29 | Y | A | 0.0000 | |
| 30 | G | A | -0.8136 | |
| 31 | N | A | -1.0169 | |
| 32 | P | A | -1.2164 | |
| 33 | Q | A | -1.6195 | |
| 34 | G | A | -1.2019 | |
| 35 | K | A | -1.1524 | |
| 36 | P | A | -0.8722 | |
| 37 | V | A | 0.0000 | |
| 38 | V | A | 0.0000 | |
| 39 | F | A | 0.0000 | |
| 40 | L | A | 0.0000 | |
| 41 | H | A | 0.0000 | |
| 42 | G | A | -0.1724 | |
| 43 | G | A | 0.0000 | |
| 44 | P | A | 0.0000 | |
| 45 | G | A | 0.0000 | |
| 46 | G | A | -0.2289 | |
| 47 | G | A | -0.6459 | |
| 48 | A | A | -0.7677 | |
| 49 | S | A | -0.7915 | |
| 50 | D | A | -1.2371 | |
| 51 | S | A | -0.7974 | |
| 52 | D | A | -0.5423 | |
| 53 | A | A | 0.0000 | |
| 54 | R | A | -0.5360 | |
| 55 | R | A | 0.0000 | |
| 56 | F | A | 0.0000 | |
| 57 | N | A | -0.4485 | |
| 58 | P | A | -0.3492 | |
| 59 | T | A | -0.5842 | |
| 60 | T | A | -0.9192 | |
| 61 | Y | A | 0.0000 | |
| 62 | R | A | -0.9637 | |
| 63 | I | A | 0.0000 | |
| 64 | V | A | 0.0000 | |
| 65 | L | A | 0.0000 | |
| 66 | F | A | 0.0000 | |
| 67 | D | A | 0.0000 | |
| 68 | Q | A | 0.0000 | |
| 69 | R | A | 0.0000 | |
| 70 | G | A | 0.0000 | |
| 71 | S | A | 0.0000 | |
| 72 | G | A | -1.3999 | |
| 73 | E | A | -1.9897 | |
| 74 | S | A | 0.0000 | |
| 75 | T | A | -0.7844 | |
| 76 | P | A | -0.5640 | |
| 77 | A | A | -0.5297 | |
| 78 | S | A | -0.3237 | |
| 79 | C | A | -0.5601 | |
| 80 | L | A | -1.0901 | |
| 81 | E | A | -2.3185 | |
| 82 | D | A | -2.2926 | |
| 83 | N | A | 0.0000 | |
| 84 | T | A | -0.9513 | |
| 85 | T | A | 0.0000 | |
| 86 | Q | A | -1.5058 | |
| 87 | A | A | 0.0000 | |
| 88 | L | A | 0.0000 | |
| 89 | V | A | 0.0000 | |
| 90 | E | A | -2.2534 | |
| 91 | D | A | 0.0000 | |
| 92 | I | A | 0.0000 | |
| 93 | E | A | -1.6490 | |
| 94 | K | A | -1.9853 | |
| 95 | I | A | 0.0000 | |
| 96 | R | A | 0.0000 | |
| 97 | E | A | -2.2080 | |
| 98 | F | A | -0.6165 | |
| 99 | L | A | 0.0000 | |
| 100 | Q | A | -1.7703 | |
| 101 | V | A | 0.0000 | |
| 102 | G | A | -1.2266 | |
| 103 | A | A | -0.7877 | |
| 104 | A | A | -0.6135 | |
| 105 | W | A | 0.0000 | |
| 106 | H | A | 0.0000 | |
| 107 | V | A | 0.0000 | |
| 108 | F | A | 0.0000 | |
| 109 | G | A | 0.0000 | |
| 110 | G | A | 0.0000 | |
| 111 | S | A | 0.0000 | |
| 112 | W | A | 0.0000 | |
| 113 | G | A | 0.0000 | |
| 114 | S | A | 0.0000 | |
| 115 | T | A | 0.0000 | |
| 116 | L | A | 0.0000 | |
| 117 | A | A | 0.0000 | |
| 118 | L | A | 0.0000 | |
| 119 | A | A | -0.2339 | |
| 120 | Y | A | 0.0000 | |
| 121 | A | A | 0.0000 | |
| 122 | Q | A | 0.0000 | |
| 123 | A | A | -0.6403 | |
| 124 | H | A | -0.8125 | |
| 125 | P | A | -0.8332 | |
| 126 | A | A | -0.5645 | |
| 127 | R | A | -0.8876 | |
| 128 | V | A | 0.0000 | |
| 129 | K | A | -0.8254 | |
| 130 | S | A | 0.0000 | |
| 131 | L | A | 0.0000 | |
| 132 | T | A | 0.0000 | |
| 133 | L | A | 0.0000 | |
| 134 | R | A | -0.0994 | |
| 135 | G | A | 0.0000 | |
| 136 | I | A | 0.0000 | |
| 137 | F | A | 0.0000 | |
| 138 | T | A | 0.0000 | |
| 139 | L | A | 0.0000 | |
| 140 | R | A | 0.0000 | |
| 141 | K | A | -2.9162 | |
| 142 | K | A | -2.7359 | |
| 143 | E | A | 0.0000 | |
| 144 | L | A | 0.0000 | |
| 145 | D | A | -1.9068 | |
| 146 | F | A | 0.0000 | |
| 147 | F | A | 0.0000 | |
| 148 | Y | A | 0.0000 | |
| 149 | Q | A | -1.2264 | |
| 150 | G | A | -0.7360 | |
| 151 | P | A | -0.6814 | |
| 152 | G | A | 0.0000 | |
| 153 | S | A | 0.0000 | |
| 154 | S | A | 0.0000 | |
| 155 | R | A | -0.3297 | mutated: FR155A |
| 156 | K | A | 0.0000 | mutated: IK156A |
| 157 | F | A | 0.0000 | |
| 158 | P | A | -0.0761 | |
| 159 | A | A | -0.0309 | mutated: EA159A |
| 160 | Y | A | -0.1545 | |
| 161 | W | A | -0.3016 | |
| 162 | A | A | -0.6330 | mutated: EA162A |
| 163 | E | A | -1.2923 | |
| 164 | Y | A | 0.0000 | |
| 165 | L | A | -0.7320 | |
| 166 | D | A | -1.7834 | |
| 167 | P | A | -1.0561 | |
| 168 | I | A | 0.0000 | |
| 169 | P | A | -0.0200 | |
| 170 | V | A | 0.9717 | |
| 171 | A | A | 0.0057 | |
| 172 | E | A | -1.2581 | |
| 173 | R | A | -1.4053 | |
| 174 | G | A | -1.6082 | |
| 175 | D | A | -2.4523 | |
| 176 | M | A | 0.0000 | |
| 177 | V | A | -1.0715 | |
| 178 | K | A | -1.8346 | |
| 179 | A | A | 0.0000 | |
| 180 | Y | A | 0.0000 | |
| 181 | Y | A | -1.0456 | |
| 182 | E | A | -2.2218 | |
| 183 | R | A | -2.1886 | |
| 184 | L | A | 0.0000 | |
| 185 | T | A | -1.2993 | |
| 186 | G | A | -1.9012 | |
| 187 | S | A | -2.0046 | |
| 188 | D | A | -3.0375 | |
| 189 | E | A | -3.6831 | |
| 190 | K | A | -3.3489 | |
| 191 | V | A | -2.1255 | |
| 192 | R | A | -2.8373 | |
| 193 | A | A | -2.7518 | |
| 194 | E | A | -3.0114 | |
| 195 | A | A | 0.0000 | |
| 196 | G | A | 0.0000 | |
| 197 | R | A | -2.3841 | |
| 198 | A | A | -1.7134 | |
| 199 | W | A | 0.0000 | |
| 200 | S | A | 0.0000 | |
| 201 | R | A | -1.0794 | |
| 202 | W | A | 0.0000 | |
| 203 | E | A | 0.0000 | |
| 204 | M | A | 0.0000 | |
| 205 | A | A | 0.0000 | |
| 206 | T | A | 0.0000 | |
| 207 | S | A | 0.0000 | |
| 208 | R | A | -0.5397 | |
| 209 | L | A | -1.0494 | |
| 210 | H | A | -1.4342 | |
| 211 | V | A | -0.5125 | |
| 212 | D | A | -1.0212 | |
| 213 | P | A | -1.2733 | |
| 214 | D | A | -2.0153 | |
| 215 | Y | A | -1.2321 | |
| 216 | I | A | -1.1836 | |
| 217 | S | A | -1.8293 | |
| 218 | K | A | -1.9432 | |
| 219 | A | A | 0.0000 | |
| 220 | D | A | -2.5644 | |
| 221 | A | A | -1.4143 | |
| 222 | P | A | -1.4323 | |
| 223 | G | A | -0.7938 | |
| 224 | F | A | -0.5815 | |
| 225 | A | A | 0.0000 | |
| 226 | D | A | -0.9179 | |
| 227 | A | A | 0.0000 | |
| 228 | F | A | 0.0000 | |
| 229 | A | A | 0.0000 | |
| 230 | R | A | -0.5038 | |
| 231 | I | A | 0.0000 | |
| 232 | E | A | 0.0000 | |
| 233 | S | A | 0.0000 | |
| 234 | H | A | -0.3605 | |
| 235 | Y | A | 0.0000 | |
| 236 | F | A | 0.0000 | |
| 237 | V | A | -0.3738 | |
| 238 | N | A | -0.6257 | |
| 239 | G | A | -1.0131 | |
| 240 | G | A | 0.0000 | |
| 241 | F | A | -0.2672 | |
| 242 | M | A | -0.6789 | |
| 243 | P | A | -1.2872 | |
| 244 | E | A | -2.6667 | |
| 245 | G | A | -1.8295 | |
| 246 | E | A | -1.6022 | |
| 247 | L | A | 0.0000 | |
| 248 | L | A | 0.0000 | |
| 249 | K | A | -1.7651 | |
| 250 | P | A | -1.5570 | |
| 251 | E | A | -2.4641 | |
| 252 | N | A | 0.0000 | |
| 253 | I | A | 0.0000 | |
| 254 | A | A | -1.3327 | |
| 255 | K | A | -1.6925 | |
| 256 | I | A | 0.0000 | |
| 257 | S | A | -1.2333 | |
| 258 | H | A | -1.5867 | |
| 259 | I | A | 0.0000 | |
| 260 | P | A | -0.9736 | |
| 261 | A | A | 0.0000 | |
| 262 | V | A | 0.0000 | |
| 263 | I | A | 0.0000 | |
| 264 | V | A | 0.0000 | |
| 265 | Q | A | 0.0000 | |
| 266 | G | A | 0.0000 | |
| 267 | A | A | -0.1900 | mutated: RA267A |
| 268 | Y | A | 0.0000 | |
| 269 | D | A | 0.0000 | |
| 270 | M | A | 0.0000 | |
| 271 | V | A | 0.0000 | |
| 272 | C | A | 0.0000 | |
| 273 | P | A | 0.0000 | |
| 274 | I | A | 0.0000 | |
| 275 | T | A | -0.1593 | |
| 276 | T | A | 0.0000 | |
| 277 | A | A | 0.0000 | |
| 278 | Y | A | 0.2443 | |
| 279 | E | A | -0.4391 | |
| 280 | L | A | 0.0000 | |
| 281 | T | A | -0.3348 | |
| 282 | A | A | -0.0769 | mutated: KA282A |
| 283 | L | A | 0.0901 | |
| 284 | W | A | 0.0000 | |
| 285 | P | A | -1.0953 | |
| 286 | E | A | -2.2981 | |
| 287 | A | A | 0.0000 | |
| 288 | K | A | -1.3299 | |
| 289 | F | A | 0.0913 | |
| 290 | V | A | 0.6488 | |
| 291 | V | A | 0.7808 | |
| 292 | I | A | 0.0000 | |
| 293 | P | A | -0.5679 | |
| 294 | D | A | -1.7027 | |
| 295 | A | A | 0.0000 | |
| 296 | G | A | 0.0000 | |
| 297 | H | A | 0.0000 | |
| 298 | S | A | 0.0000 | |
| 299 | A | A | 0.1361 | |
| 300 | I | A | 0.6555 | |
| 301 | E | A | 0.0000 | |
| 302 | A | A | -0.1464 | |
| 303 | G | A | -0.5471 | |
| 304 | T | A | 0.0000 | |
| 305 | E | A | -0.6912 | |
| 306 | K | A | -1.4944 | |
| 307 | A | A | -1.2380 | |
| 308 | L | A | 0.0000 | |
| 309 | V | A | 0.0000 | |
| 310 | E | A | -2.6970 | |
| 311 | A | A | 0.0000 | |
| 312 | T | A | 0.0000 | |
| 313 | E | A | -2.2332 | |
| 314 | E | A | -2.4045 | |
| 315 | F | A | 0.0000 | |
| 316 | A | A | -1.6110 | |
| 317 | K | A | -2.0515 | |
| 318 | L | A | -0.9128 | |
| 319 | A | A | -0.3415 | |
| 1 | M | B | 0.9346 | |
| 2 | T | B | 0.4523 | |
| 3 | S | B | -0.2943 | |
| 4 | L | B | 0.1777 | |
| 5 | F | B | 0.3348 | |
| 6 | A | B | 0.1267 | |
| 7 | A | B | -0.1692 | |
| 8 | I | B | -0.3800 | |
| 9 | Q | B | -1.2862 | |
| 10 | P | B | -0.8165 | |
| 11 | Y | B | -0.1749 | |
| 12 | K | B | -1.1345 | |
| 13 | T | B | -0.4224 | |
| 14 | H | B | -0.0198 | |
| 15 | L | B | 0.4981 | |
| 16 | L | B | -0.2853 | |
| 17 | R | B | -1.8264 | |
| 18 | V | B | 0.0000 | |
| 19 | S | B | -0.7977 | |
| 20 | P | B | -0.4240 | |
| 21 | L | B | -0.4619 | |
| 22 | H | B | 0.0000 | |
| 23 | R | B | -1.3761 | |
| 24 | L | B | 0.0000 | |
| 25 | S | B | 0.0000 | |
| 26 | I | B | 0.0000 | |
| 27 | K | B | -0.8182 | |
| 28 | E | B | 0.0000 | |
| 29 | Y | B | 0.0000 | |
| 30 | G | B | -0.7257 | |
| 31 | N | B | -0.9387 | |
| 32 | P | B | -1.0712 | |
| 33 | Q | B | -1.5613 | |
| 34 | G | B | -1.1519 | |
| 35 | K | B | -1.0619 | |
| 36 | P | B | -0.7582 | |
| 37 | V | B | 0.0000 | |
| 38 | V | B | 0.0000 | |
| 39 | F | B | 0.0000 | |
| 40 | L | B | 0.0000 | |
| 41 | H | B | 0.0000 | |
| 42 | G | B | -0.1673 | |
| 43 | G | B | 0.0000 | |
| 44 | P | B | 0.0000 | |
| 45 | G | B | 0.0000 | |
| 46 | G | B | -0.2025 | |
| 47 | G | B | -0.6306 | |
| 48 | A | B | -0.7655 | |
| 49 | S | B | -0.7876 | |
| 50 | D | B | -1.2270 | |
| 51 | S | B | -0.7973 | |
| 52 | D | B | -0.5997 | |
| 53 | A | B | 0.0000 | |
| 54 | R | B | -0.5319 | |
| 55 | R | B | 0.0000 | |
| 56 | F | B | 0.0000 | |
| 57 | N | B | -0.5032 | |
| 58 | P | B | -0.3302 | |
| 59 | T | B | -0.5708 | |
| 60 | T | B | -0.9423 | |
| 61 | Y | B | 0.0000 | |
| 62 | R | B | -0.8887 | |
| 63 | I | B | 0.0000 | |
| 64 | V | B | 0.0000 | |
| 65 | L | B | 0.0000 | |
| 66 | F | B | 0.0000 | |
| 67 | D | B | 0.0000 | |
| 68 | Q | B | 0.0000 | |
| 69 | R | B | 0.0000 | |
| 70 | G | B | 0.0000 | |
| 71 | S | B | 0.0000 | |
| 72 | G | B | -1.3883 | |
| 73 | E | B | -2.0037 | |
| 74 | S | B | 0.0000 | |
| 75 | T | B | -0.7940 | |
| 76 | P | B | -0.5609 | |
| 77 | A | B | -0.5143 | |
| 78 | S | B | 0.0000 | |
| 79 | C | B | -0.5458 | |
| 80 | L | B | -1.0785 | |
| 81 | E | B | -2.3045 | |
| 82 | D | B | -2.2684 | |
| 83 | N | B | 0.0000 | |
| 84 | T | B | -0.9416 | |
| 85 | T | B | 0.0000 | |
| 86 | Q | B | -1.5645 | |
| 87 | A | B | -1.4291 | |
| 88 | L | B | 0.0000 | |
| 89 | V | B | 0.0000 | |
| 90 | E | B | -2.3819 | |
| 91 | D | B | 0.0000 | |
| 92 | I | B | 0.0000 | |
| 93 | E | B | -1.6830 | |
| 94 | K | B | -1.9873 | |
| 95 | I | B | 0.0000 | |
| 96 | R | B | 0.0000 | |
| 97 | E | B | -2.1491 | |
| 98 | F | B | -0.5657 | |
| 99 | L | B | 0.0000 | |
| 100 | Q | B | -1.6670 | |
| 101 | V | B | -1.0837 | |
| 102 | G | B | -1.1237 | |
| 103 | A | B | -0.7233 | |
| 104 | A | B | -0.5142 | |
| 105 | W | B | 0.0000 | |
| 106 | H | B | 0.0000 | |
| 107 | V | B | 0.0000 | |
| 108 | F | B | 0.0000 | |
| 109 | G | B | 0.0000 | |
| 110 | G | B | 0.0000 | |
| 111 | S | B | 0.0000 | |
| 112 | W | B | 0.0000 | |
| 113 | G | B | 0.0000 | |
| 114 | S | B | 0.0000 | |
| 115 | T | B | 0.0000 | |
| 116 | L | B | 0.0000 | |
| 117 | A | B | 0.0000 | |
| 118 | L | B | 0.0000 | |
| 119 | A | B | -0.2376 | |
| 120 | Y | B | 0.0000 | |
| 121 | A | B | 0.0000 | |
| 122 | Q | B | 0.0000 | |
| 123 | A | B | -0.6555 | |
| 124 | H | B | -0.8186 | |
| 125 | P | B | -0.7997 | |
| 126 | A | B | -0.5265 | |
| 127 | R | B | -0.8408 | |
| 128 | V | B | 0.0000 | |
| 129 | K | B | -0.5855 | |
| 130 | S | B | 0.0000 | |
| 131 | L | B | 0.0000 | |
| 132 | T | B | 0.0000 | |
| 133 | L | B | 0.0000 | |
| 134 | R | B | -0.0988 | |
| 135 | G | B | 0.0000 | |
| 136 | I | B | 0.0000 | |
| 137 | F | B | 0.0000 | |
| 138 | T | B | 0.0000 | |
| 139 | L | B | 0.0000 | |
| 140 | R | B | 0.0000 | |
| 141 | K | B | -2.7644 | |
| 142 | K | B | -2.4568 | |
| 143 | E | B | 0.0000 | |
| 144 | L | B | 0.0000 | |
| 145 | D | B | -1.7571 | |
| 146 | F | B | 0.0000 | |
| 147 | F | B | 0.0000 | |
| 148 | Y | B | 0.0000 | |
| 149 | Q | B | -1.1778 | |
| 150 | G | B | -0.6908 | |
| 151 | P | B | -0.7163 | |
| 152 | G | B | 0.0000 | |
| 153 | S | B | 0.0000 | |
| 154 | S | B | 0.0000 | |
| 155 | R | B | -0.2185 | mutated: FR155B |
| 156 | K | B | 0.0000 | mutated: IK156B |
| 157 | F | B | 0.0000 | |
| 158 | P | B | -0.1026 | |
| 159 | A | B | -0.0587 | mutated: EA159B |
| 160 | Y | B | -0.1790 | |
| 161 | W | B | -0.3243 | |
| 162 | A | B | -0.6603 | mutated: EA162B |
| 163 | E | B | -1.3626 | |
| 164 | Y | B | 0.0000 | |
| 165 | L | B | -0.7540 | |
| 166 | D | B | -1.8058 | |
| 167 | P | B | -1.1178 | |
| 168 | I | B | 0.0000 | |
| 169 | P | B | -0.0658 | |
| 170 | V | B | 0.9740 | |
| 171 | A | B | 0.0072 | |
| 172 | E | B | -1.2512 | |
| 173 | R | B | -1.4046 | |
| 174 | G | B | -1.6249 | |
| 175 | D | B | -2.4544 | |
| 176 | M | B | 0.0000 | |
| 177 | V | B | -1.0559 | |
| 178 | K | B | -1.8214 | |
| 179 | A | B | 0.0000 | |
| 180 | Y | B | 0.0000 | |
| 181 | Y | B | -1.0449 | |
| 182 | E | B | -2.2252 | |
| 183 | R | B | -2.1801 | |
| 184 | L | B | 0.0000 | |
| 185 | T | B | -1.2929 | |
| 186 | G | B | -1.8810 | |
| 187 | S | B | -1.9691 | |
| 188 | D | B | -2.9649 | |
| 189 | E | B | -3.6521 | |
| 190 | K | B | -3.3213 | |
| 191 | V | B | -2.0881 | |
| 192 | R | B | -2.8451 | |
| 193 | A | B | -2.7561 | |
| 194 | E | B | -3.0182 | |
| 195 | A | B | 0.0000 | |
| 196 | G | B | 0.0000 | |
| 197 | R | B | -2.3937 | |
| 198 | A | B | -1.7324 | |
| 199 | W | B | 0.0000 | |
| 200 | S | B | 0.0000 | |
| 201 | R | B | -1.0797 | |
| 202 | W | B | 0.0000 | |
| 203 | E | B | 0.0000 | |
| 204 | M | B | 0.0000 | |
| 205 | A | B | 0.0000 | |
| 206 | T | B | 0.0000 | |
| 207 | S | B | 0.0000 | |
| 208 | R | B | -0.5071 | |
| 209 | L | B | -0.9101 | |
| 210 | H | B | -1.0375 | |
| 211 | V | B | -0.1517 | |
| 212 | D | B | -0.8411 | |
| 213 | P | B | -1.1847 | |
| 214 | D | B | -1.9790 | |
| 215 | Y | B | -1.1798 | |
| 216 | I | B | -1.1407 | |
| 217 | S | B | -1.8227 | |
| 218 | K | B | -1.9145 | |
| 219 | A | B | 0.0000 | |
| 220 | D | B | -2.5623 | |
| 221 | A | B | -1.4010 | |
| 222 | P | B | -1.4237 | |
| 223 | G | B | -0.7721 | |
| 224 | F | B | -0.5377 | |
| 225 | A | B | 0.0000 | |
| 226 | D | B | -0.9151 | |
| 227 | A | B | 0.0000 | |
| 228 | F | B | 0.0000 | |
| 229 | A | B | 0.0000 | |
| 230 | R | B | -0.5013 | |
| 231 | I | B | 0.0000 | |
| 232 | E | B | 0.0000 | |
| 233 | S | B | 0.0000 | |
| 234 | H | B | -0.3381 | |
| 235 | Y | B | 0.0000 | |
| 236 | F | B | 0.0000 | |
| 237 | V | B | -0.3319 | |
| 238 | N | B | -0.5416 | |
| 239 | G | B | -0.9706 | |
| 240 | G | B | 0.0000 | |
| 241 | F | B | -0.2371 | |
| 242 | M | B | -0.6658 | |
| 243 | P | B | -1.2760 | |
| 244 | E | B | -2.6490 | |
| 245 | G | B | -1.8275 | |
| 246 | E | B | -1.6316 | |
| 247 | L | B | 0.0000 | |
| 248 | L | B | 0.0000 | |
| 249 | K | B | -1.8665 | |
| 250 | P | B | -1.6079 | |
| 251 | E | B | -2.4963 | |
| 252 | N | B | 0.0000 | |
| 253 | I | B | 0.0000 | |
| 254 | A | B | -1.3479 | |
| 255 | K | B | -1.6932 | |
| 256 | I | B | 0.0000 | |
| 257 | S | B | -1.2415 | |
| 258 | H | B | -1.5928 | |
| 259 | I | B | 0.0000 | |
| 260 | P | B | -0.9627 | |
| 261 | A | B | 0.0000 | |
| 262 | V | B | 0.0000 | |
| 263 | I | B | 0.0000 | |
| 264 | V | B | 0.0000 | |
| 265 | Q | B | 0.0000 | |
| 266 | G | B | 0.0000 | |
| 267 | A | B | -0.3648 | mutated: RA267B |
| 268 | Y | B | 0.0000 | |
| 269 | D | B | 0.0000 | |
| 270 | M | B | 0.0000 | |
| 271 | V | B | 0.0000 | |
| 272 | C | B | 0.0000 | |
| 273 | P | B | 0.0000 | |
| 274 | I | B | 0.0000 | |
| 275 | T | B | 0.0000 | |
| 276 | T | B | 0.0000 | |
| 277 | A | B | 0.0000 | |
| 278 | Y | B | 0.2897 | |
| 279 | E | B | -0.3363 | |
| 280 | L | B | 0.0000 | |
| 281 | T | B | -0.3455 | |
| 282 | A | B | -0.0407 | mutated: KA282B |
| 283 | L | B | 0.1054 | |
| 284 | W | B | 0.0000 | |
| 285 | P | B | -1.1437 | |
| 286 | E | B | -2.3640 | |
| 287 | A | B | 0.0000 | |
| 288 | K | B | -1.6152 | |
| 289 | F | B | -0.0879 | |
| 290 | V | B | 0.4897 | |
| 291 | V | B | 0.6533 | |
| 292 | I | B | 0.0000 | |
| 293 | P | B | -0.9359 | |
| 294 | D | B | -2.2138 | |
| 295 | A | B | 0.0000 | |
| 296 | G | B | 0.0000 | |
| 297 | H | B | 0.0000 | |
| 298 | S | B | 0.0000 | |
| 299 | A | B | 0.0522 | |
| 300 | I | B | 0.4286 | |
| 301 | E | B | 0.0000 | |
| 302 | A | B | -0.2400 | |
| 303 | G | B | -0.6500 | |
| 304 | T | B | 0.0000 | |
| 305 | E | B | 0.0000 | |
| 306 | K | B | -1.4424 | |
| 307 | A | B | -1.2255 | |
| 308 | L | B | 0.0000 | |
| 309 | V | B | 0.0000 | |
| 310 | E | B | -2.8199 | |
| 311 | A | B | 0.0000 | |
| 312 | T | B | 0.0000 | |
| 313 | E | B | -2.6074 | |
| 314 | E | B | -2.7253 | |
| 315 | F | B | 0.0000 | |
| 316 | A | B | -1.7523 | |
| 317 | K | B | -2.1429 | |
| 318 | L | B | -0.8922 | |
| 319 | A | B | -0.2830 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine