Project name: gp63_004

Chain sequence(s)	H: QVQLVESGGGLVQPGGSLRLSCAASGDSSFDFSQYSLGWFRQAPGQGLEAVAAISADGSQTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAASKSTQLKNILPESFDYWGQGTLVTVS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:10)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:11)

• Minimal score value: -3.1343
• Maximal score value: 1.6185
• Average score: -0.8899
• Total score value: -113.0144

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5727
2	V	H	-1.1357
3	Q	H	-0.7625
4	L	H	0.0000
5	V	H	1.1479
6	E	H	0.0000
7	S	H	-0.1886
8	G	H	-0.7307
9	G	H	0.1776
10	G	H	0.7503
11	L	H	1.4414
12	V	H	-0.0694
13	Q	H	-1.4157
14	P	H	-1.8777
15	G	H	-1.6970
16	G	H	-1.2032
17	S	H	-1.4287
18	L	H	-1.0187
19	R	H	-2.2271
20	L	H	0.0000
21	S	H	-0.4459
22	C	H	0.0000
23	A	H	-0.1601
24	A	H	-0.4776
25	S	H	-0.9762
26	G	H	-1.3939
27	D	H	-1.7920
28	S	H	-1.0363
29	S	H	-0.6942
30	F	H	-0.7508
31	D	H	-1.5206
32	F	H	0.0000
33	S	H	-2.1201
34	Q	H	-2.2900
35	Y	H	0.0000
36	S	H	0.0000
37	L	H	0.0000
38	G	H	0.0000
39	W	H	0.0000
40	F	H	0.0000
41	R	H	0.0000
42	Q	H	-0.7157
43	A	H	-0.9900
44	P	H	-0.9779
45	G	H	-1.2998
46	Q	H	-1.8473
47	G	H	-1.2534
48	L	H	-0.4102
49	E	H	-0.7477
50	A	H	-0.1918
51	V	H	0.0000
52	A	H	0.0000
53	A	H	0.0000
54	I	H	0.0000
55	S	H	-1.7117
56	A	H	-2.1878
57	D	H	-2.6771
58	G	H	-1.8816
59	S	H	-1.4935
60	Q	H	-2.0095
61	T	H	-0.8599
62	Y	H	0.0000
63	Y	H	-0.7328
64	A	H	-1.3451
65	D	H	-2.4537
66	S	H	-1.7666
67	V	H	0.0000
68	K	H	-2.5894
69	G	H	-1.8664
70	R	H	-1.8629
71	F	H	0.0000
72	T	H	-1.0853
73	I	H	0.0000
74	S	H	-0.6724
75	R	H	-1.6085
76	D	H	-2.4375
77	N	H	-3.1343
78	S	H	-2.1100
79	K	H	-2.7973
80	N	H	-2.3572
81	T	H	-1.3794
82	L	H	0.0000
83	Y	H	0.0000
84	L	H	0.0000
85	Q	H	-1.6954
86	M	H	0.0000
87	N	H	-2.2741
88	S	H	-1.7327
89	L	H	0.0000
90	R	H	-3.0199
91	A	H	-2.0327
92	E	H	-2.4587
93	D	H	0.0000
94	T	H	-0.5169
95	A	H	0.0000
96	V	H	0.7995
97	Y	H	0.0000
98	Y	H	0.3328
99	C	H	0.0000
100	A	H	0.0000
101	A	H	0.0000
102	S	H	0.0000
103	K	H	-2.6608
104	S	H	-1.7572
105	T	H	-1.8936
106	Q	H	-2.2078
107	L	H	-1.8247
108	K	H	-2.5882
109	N	H	-2.2190
110	I	H	-1.0739
111	L	H	-0.5658
112	P	H	-0.9371
113	E	H	-2.0694
114	S	H	-1.6531
115	F	H	0.0000
116	D	H	-2.2240
117	Y	H	-0.9174
118	W	H	-0.0463
119	G	H	-0.0016
120	Q	H	-0.6595
121	G	H	0.1049
122	T	H	0.6420
123	L	H	1.6185
124	V	H	0.0000
125	T	H	0.3046
126	V	H	0.0000
127	S	H	-0.8650