Project name: gp63_004

Chain sequence(s)	H: QVQLVESGGGLVQPGGSLRLSCAASGSMSAPFSSYSLGWFRQAPGQGLEAVAAIDPDGSVTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAASPNPHAQLMSPSAYDYWGQGTLVTVS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:29)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:30)

• Minimal score value: -2.4658
• Maximal score value: 1.7109
• Average score: -0.5969
• Total score value: -75.8004

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.6536
2	V	H	0.0000
3	Q	H	-1.0986
4	L	H	0.0000
5	V	H	0.8358
6	E	H	0.0000
7	S	H	-0.2594
8	G	H	-0.6260
9	G	H	0.1331
10	G	H	0.6830
11	L	H	1.3870
12	V	H	-0.0197
13	Q	H	-1.3287
14	P	H	-1.6705
15	G	H	-1.5293
16	G	H	-1.0819
17	S	H	-1.3343
18	L	H	-1.0660
19	R	H	-2.3618
20	L	H	0.0000
21	S	H	-0.5309
22	C	H	0.0000
23	A	H	-0.2352
24	A	H	0.0000
25	S	H	-1.0242
26	G	H	-1.3503
27	S	H	-1.0591
28	M	H	-0.7677
29	S	H	-0.5230
30	A	H	-0.3027
31	P	H	-0.5781
32	F	H	0.0000
33	S	H	-1.3130
34	S	H	-0.9016
35	Y	H	0.0000
36	S	H	0.0000
37	L	H	0.0000
38	G	H	0.0000
39	W	H	0.0000
40	F	H	0.0000
41	R	H	0.0000
42	Q	H	-0.7368
43	A	H	-1.0223
44	P	H	-0.9257
45	G	H	-1.2963
46	Q	H	-1.8481
47	G	H	-1.2512
48	L	H	-0.5290
49	E	H	-0.9181
50	A	H	-0.1738
51	V	H	0.0000
52	A	H	0.0000
53	A	H	0.0000
54	I	H	0.0000
55	D	H	-1.0239
56	P	H	-1.5096
57	D	H	-2.0449
58	G	H	-1.0836
59	S	H	-0.3085
60	V	H	0.7172
61	T	H	0.8183
62	Y	H	0.9613
63	Y	H	-0.3081
64	A	H	-1.2059
65	D	H	-2.3185
66	S	H	-1.7955
67	V	H	0.0000
68	K	H	-2.4444
69	G	H	-1.8022
70	R	H	-1.5404
71	F	H	0.0000
72	T	H	-0.9979
73	I	H	0.0000
74	S	H	-0.7956
75	R	H	-1.4030
76	D	H	-2.0126
77	N	H	-2.1069
78	S	H	-1.6872
79	K	H	-2.4658
80	N	H	-1.8806
81	T	H	-1.1364
82	L	H	0.0000
83	Y	H	0.0000
84	L	H	0.0000
85	Q	H	-1.7424
86	M	H	0.0000
87	N	H	-2.0967
88	S	H	-1.4988
89	L	H	0.0000
90	R	H	-2.4160
91	A	H	-1.7447
92	E	H	-2.2595
93	D	H	0.0000
94	T	H	-0.4369
95	A	H	0.0000
96	V	H	0.7492
97	Y	H	0.0000
98	Y	H	0.3110
99	C	H	0.0000
100	A	H	0.0000
101	A	H	0.0000
102	S	H	0.0000
103	P	H	-1.3562
104	N	H	-1.9639
105	P	H	-1.6739
106	H	H	-1.2870
107	A	H	0.0000
108	Q	H	0.1006
109	L	H	1.1935
110	M	H	0.8057
111	S	H	0.2701
112	P	H	-0.2340
113	S	H	-0.3971
114	A	H	-0.6101
115	Y	H	0.0000
116	D	H	-1.8231
117	Y	H	-0.8182
118	W	H	-0.1509
119	G	H	-0.1011
120	Q	H	-0.8540
121	G	H	0.0000
122	T	H	0.6245
123	L	H	1.7109
124	V	H	0.0000
125	T	H	0.3417
126	V	H	0.0000
127	S	H	-0.7904