Project name: clone35

Chain sequence(s)	H: QVQLQESGPGLVKPSETLSLTCSVSGASIKSYYWSWFRQPPGKRLEWIGYYYYSETSNYNPSLKSRVTMSLDTSKNHFSLRLRSVTAADTAIYYCAKQGGGWSAGFAEFWCAKQGGGWSAGFAEFWGQGLLVTVSS; L: QIVMTQSPATLSVSPGERATLSCRASLSVTNNLAWYQQKPGQAPRLLIYGASTRATGIPVRFSGGGSGTEFTLTISNVQSEDFAVYTCQQYNMWPLSFGGGTKVEIR
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:09)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:10)

• Minimal score value: -2.8252
• Maximal score value: 1.5166
• Average score: -0.4867
• Total score value: -118.2775

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5842
2	V	H	0.0000
3	Q	H	-1.7503
4	L	H	0.0000
5	Q	H	-1.3220
6	E	H	0.0000
7	S	H	-0.5726
8	G	H	-0.3496
9	P	H	0.0463
11	G	H	0.4553
12	L	H	0.8883
13	V	H	0.0000
14	K	H	-1.6507
15	P	H	-1.3675
16	S	H	-1.5554
17	E	H	-2.2466
18	T	H	-1.8851
19	L	H	0.0000
20	S	H	-1.2679
21	L	H	0.0000
22	T	H	-0.7196
23	C	H	0.0000
24	S	H	-1.1008
25	V	H	0.0000
26	S	H	-1.2414
27	G	H	-1.2955
28	A	H	-1.0097
29	S	H	-1.0732
30	I	H	0.0000
35	K	H	-1.3924
36	S	H	-0.5409
37	Y	H	0.1617
38	Y	H	0.0910
39	W	H	0.0000
40	S	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-0.9621
45	P	H	-0.9901
46	P	H	-1.0357
47	G	H	-1.6737
48	K	H	-2.7310
49	R	H	-2.3101
50	L	H	0.0000
51	E	H	-0.9311
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	Y	H	0.0000
56	Y	H	0.0000
57	Y	H	-0.2159
58	Y	H	-0.5443
59	S	H	-0.7933
63	E	H	-1.4092
64	T	H	-0.6938
65	S	H	-0.4986
66	N	H	-0.5556
67	Y	H	-0.5974
68	N	H	0.0000
69	P	H	-1.1092
70	S	H	-0.8863
71	L	H	0.0000
72	K	H	-2.0565
74	S	H	-1.3823
75	R	H	-1.6794
76	V	H	0.0000
77	T	H	-1.2538
78	M	H	0.0000
79	S	H	-0.7083
80	L	H	-0.9435
81	D	H	-1.4421
82	T	H	-1.3741
83	S	H	-1.3575
84	K	H	-2.2447
85	N	H	-1.8424
86	H	H	-1.3807
87	F	H	0.0000
88	S	H	-0.7301
89	L	H	0.0000
90	R	H	-2.1883
91	L	H	0.0000
92	R	H	-1.9210
93	S	H	-1.5916
94	V	H	0.0000
95	T	H	-0.6475
96	A	H	-0.2046
97	A	H	0.0538
98	D	H	0.0000
99	T	H	0.2611
100	A	H	0.0000
101	I	H	0.5120
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	K	H	0.0000
107	Q	H	0.0000
108	G	H	0.0363
109	G	H	0.3067
110	G	H	0.4398
111	W	H	1.0709
111A	S	H	0.5070
111B	A	H	0.3627
111C	G	H	0.0954
111D	F	H	0.4453
111E	A	H	-0.3021
111F	E	H	-0.5578
111G	F	H	1.5166
111H	W	H	1.3128
112I	C	H	0.3917
112H	A	H	-0.4898
112G	K	H	-1.9999
112F	Q	H	-2.0853
112E	G	H	-1.5983
112D	G	H	-0.8124
112C	G	H	0.1353
112B	W	H	0.8279
112A	S	H	0.0000
112	A	H	0.2507
113	G	H	0.0000
114	F	H	0.0000
115	A	H	0.0000
116	E	H	-0.4643
117	F	H	-0.3172
118	W	H	-0.5835
119	G	H	0.0000
120	Q	H	-1.5070
121	G	H	-0.5357
122	L	H	0.2135
123	L	H	0.8785
124	V	H	0.0000
125	T	H	0.3938
126	V	H	0.0000
127	S	H	-0.4067
128	S	H	-0.5730
1	Q	L	-0.4947
2	I	L	0.0000
3	V	L	0.9914
4	M	L	0.0000
5	T	L	-0.6706
6	Q	L	-0.8750
7	S	L	-0.8002
8	P	L	-0.4443
9	A	L	-0.3687
10	T	L	-0.4625
11	L	L	-0.1414
12	S	L	-0.3316
13	V	L	0.0000
14	S	L	-1.0625
15	P	L	-1.4240
16	G	L	-1.8823
17	E	L	-2.3479
18	R	L	-2.8252
19	A	L	0.0000
20	T	L	-0.6243
21	L	L	0.0000
22	S	L	-0.9325
23	C	L	0.0000
24	R	L	-2.0747
25	A	L	0.0000
26	S	L	0.1625
27	L	L	0.8904
28	S	L	-0.2116
29	V	L	0.0000
36	T	L	-0.8382
37	N	L	-1.4839
38	N	L	-0.8258
39	L	L	0.0000
40	A	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	-0.5368
44	Q	L	-0.7892
45	K	L	-1.2241
46	P	L	-0.8306
47	G	L	-1.3105
48	Q	L	-1.7639
49	A	L	-1.1065
50	P	L	0.0000
51	R	L	-1.0016
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	-0.1448
56	G	L	-0.5999
57	A	L	0.0000
65	S	L	-0.7580
66	T	L	-0.5768
67	R	L	-0.5846
68	A	L	0.0000
69	T	L	-0.5191
70	G	L	-0.3353
71	I	L	-0.0114
72	P	L	0.4608
74	V	L	1.3750
75	R	L	-0.1235
76	F	L	0.0000
77	S	L	-0.1083
78	G	L	-0.5029
79	G	L	-0.8754
80	G	L	-1.4485
83	S	L	-1.4698
84	G	L	-0.9498
85	T	L	-1.1637
86	E	L	-2.0060
87	F	L	0.0000
88	T	L	-0.8461
89	L	L	0.0000
90	T	L	-0.7334
91	I	L	0.0000
92	S	L	-1.7479
93	N	L	-2.5254
94	V	L	0.0000
95	Q	L	-1.5950
96	S	L	-0.9245
97	E	L	-1.8637
98	D	L	0.0000
99	F	L	-0.2938
100	A	L	0.0000
101	V	L	-0.1461
102	Y	L	0.0000
103	T	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	Q	L	0.0000
107	Y	L	0.0000
108	N	L	-0.0821
109	M	L	0.5254
114	W	L	0.4437
115	P	L	0.0000
116	L	L	0.0000
117	S	L	0.0000
118	F	L	0.0000
119	G	L	0.0000
120	G	L	-1.0139
121	G	L	-0.9636
122	T	L	0.0000
123	K	L	-0.8466
124	V	L	0.0000
125	E	L	-0.0206
126	I	L	0.7414
127	R	L	-1.0127