Chain sequence(s) |
G: MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
input PDB |
Selected Chain(s) | G |
Distance of aggregation | 10 Å |
FoldX usage | Yes |
Dynamic mode | No |
Automated mutations | No |
Downloads | Download all the data |
Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00) [WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow to prevent this behavior) (00:00:00) [INFO] runJob: Starting aggrescan3d job on: input.pdb with G chain(s) selected (00:00:00) [INFO] runJob: Creating pdb object from: input.pdb (00:00:00) [INFO] FoldX: Starting FoldX energy minimalization (00:00:00) [INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:01:36) [INFO] Main: Simulation completed successfully. (00:01:37) |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
1 | M | G | -0.3978 | |
2 | D | G | -1.2453 | |
3 | V | G | -0.0162 | |
4 | T | G | 0.1825 | |
5 | I | G | 1.6151 | |
6 | Q | G | -0.0233 | |
7 | H | G | -0.2564 | |
8 | P | G | 0.0000 | |
9 | W | G | 1.5520 | |
10 | F | G | 1.9997 | |
11 | K | G | 0.0000 | |
12 | R | G | 0.0000 | |
13 | T | G | 0.0000 | |
14 | L | G | 0.8708 | |
15 | G | G | 0.4970 | |
16 | P | G | 0.0000 | |
17 | F | G | 0.9788 | |
18 | Y | G | 0.5142 | |
19 | P | G | 0.0000 | |
20 | S | G | 0.0000 | |
21 | R | G | -0.5662 | |
22 | L | G | -0.0816 | |
23 | F | G | 0.0000 | |
24 | D | G | -0.5516 | |
25 | Q | G | -1.3273 | |
26 | F | G | 0.0420 | |
27 | F | G | -0.2549 | |
28 | G | G | -0.9034 | |
29 | E | G | -1.5240 | |
30 | G | G | -0.2685 | |
31 | L | G | 1.2317 | |
32 | F | G | 1.1634 | |
33 | E | G | -0.3900 | |
34 | Y | G | 0.4901 | |
35 | D | G | 0.4056 | |
36 | L | G | 1.8493 | |
37 | L | G | 1.5860 | |
38 | P | G | 1.3791 | |
39 | F | G | 1.6838 | |
40 | L | G | 1.5054 | |
41 | S | G | 1.1272 | |
42 | S | G | 0.7898 | |
43 | T | G | 0.2229 | |
44 | I | G | 0.0000 | |
45 | S | G | 0.0830 | |
46 | P | G | 0.2364 | |
47 | Y | G | 0.3795 | |
48 | Y | G | 0.3545 | |
49 | R | G | -1.2903 | |
50 | Q | G | -0.8492 | |
51 | S | G | -0.7859 | |
52 | L | G | -0.1151 | |
53 | F | G | 0.0000 | |
54 | R | G | -1.9672 | |
55 | T | G | -0.9664 | |
56 | V | G | -0.2947 | |
57 | L | G | -0.8632 | |
58 | D | G | -1.9680 | |
59 | S | G | -1.3346 | |
60 | G | G | -1.0969 | |
61 | I | G | -0.6683 | |
62 | S | G | 0.0000 | |
63 | E | G | -1.0763 | |
64 | V | G | 0.0000 | |
65 | R | G | -0.5729 | |
66 | S | G | 0.0000 | |
67 | D | G | -1.7350 | |
68 | R | G | -2.6336 | |
69 | D | G | -1.7263 | |
70 | K | G | -1.9043 | |
71 | F | G | 0.0000 | |
72 | V | G | -0.0774 | |
73 | I | G | 0.0000 | |
74 | F | G | 0.0657 | |
75 | L | G | 0.0000 | |
76 | D | G | -2.0517 | |
77 | V | G | -1.7222 | |
78 | K | G | -2.8133 | |
79 | H | G | -2.8802 | |
80 | F | G | 0.0000 | |
81 | S | G | -1.9475 | |
82 | P | G | -1.6422 | |
83 | E | G | -2.3010 | |
84 | D | G | -2.1797 | |
85 | L | G | 0.0000 | |
86 | T | G | -0.8616 | |
87 | V | G | 0.0000 | |
88 | K | G | -2.4309 | |
89 | V | G | -2.5468 | |
90 | Q | G | -2.3650 | |
91 | D | G | -1.6255 | |
92 | D | G | 0.0000 | |
93 | F | G | -1.2709 | |
94 | V | G | 0.0000 | |
95 | E | G | -2.4237 | |
96 | I | G | 0.0000 | |
97 | H | G | -2.0521 | |
98 | G | G | 0.0000 | |
99 | K | G | -3.8596 | |
100 | H | G | -3.1539 | |
101 | N | G | -2.3314 | |
102 | E | G | -2.1474 | |
103 | R | G | -3.1730 | |
104 | Q | G | -3.4716 | |
105 | D | G | -3.9293 | |
106 | D | G | -3.6937 | |
107 | H | G | -2.6356 | |
108 | G | G | -1.3907 | |
109 | Y | G | 0.4649 | |
110 | I | G | -0.3215 | |
111 | S | G | -1.8616 | |
112 | R | G | -3.7542 | |
113 | E | G | -3.8058 | |
114 | F | G | -2.0700 | |
115 | H | G | -2.4302 | |
116 | R | G | -2.1999 | |
117 | R | G | -2.9470 | |
118 | Y | G | -1.0354 | |
119 | R | G | 0.0000 | |
120 | L | G | 0.0000 | |
121 | P | G | 0.0000 | |
122 | S | G | 0.0516 | |
123 | N | G | -0.8092 | |
124 | V | G | 0.0000 | |
125 | D | G | -0.9682 | |
126 | Q | G | 0.0000 | |
127 | S | G | -1.4428 | |
128 | A | G | -0.5724 | |
129 | L | G | 0.0000 | |
130 | S | G | -0.1281 | |
131 | C | G | 0.0000 | |
132 | S | G | 0.0000 | |
133 | L | G | 0.0000 | |
134 | S | G | -1.7653 | |
135 | A | G | -1.4244 | |
136 | D | G | -2.1083 | |
137 | G | G | 0.0000 | |
138 | M | G | -0.9495 | |
139 | L | G | 0.0000 | |
140 | T | G | 0.0000 | |
141 | F | G | 0.0000 | |
142 | C | G | -0.6242 | |
143 | G | G | -0.1819 | |
144 | P | G | -0.0450 | |
145 | K | G | -0.0333 | |
146 | I | G | 1.1912 | |
147 | Q | G | -0.7603 | |
148 | T | G | -1.0050 | |
149 | G | G | -0.5954 | |
150 | L | G | 0.0161 | |
151 | D | G | -1.3579 | |
152 | A | G | -0.5228 | |
153 | T | G | -0.1719 | |
154 | H | G | 0.0000 | |
155 | A | G | -1.0099 | |
156 | E | G | -3.0410 | |
157 | R | G | -3.0286 | |
158 | A | G | -1.6135 | |
159 | I | G | 0.0000 | |
160 | P | G | -0.0456 | |
161 | V | G | 0.7497 | |
162 | S | G | -0.5272 | |
163 | R | G | -2.4835 | |
164 | E | G | -2.3333 | |
165 | E | G | -3.2117 | |
166 | K | G | -2.8638 | |
167 | P | G | -2.0946 | |
168 | T | G | -1.3229 | |
169 | S | G | -1.2948 | |
170 | A | G | -0.2135 | |
171 | P | G | -0.2129 | |
172 | S | G | -0.4304 | |
173 | S | G | -0.3961 |