Project name: 49746bb6e12bd82

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYGMGWFRQAPGKGRELVAAINSNGGSTYYPDSVEGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCASGDYWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:48)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:49)

• Minimal score value: -2.7646
• Maximal score value: 1.226
• Average score: -0.7529
• Total score value: -84.3233

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.1501
2	V	A	-1.1512
3	Q	A	-1.1129
4	L	A	0.0000
5	V	A	1.2260
6	E	A	0.0000
7	S	A	-0.4884
8	G	A	-1.0694
9	G	A	-0.7911
10	G	A	-0.0662
11	L	A	0.9311
12	V	A	0.0000
13	Q	A	-1.3677
14	P	A	-1.5602
15	G	A	-1.4464
16	G	A	-1.0758
17	S	A	-1.4177
18	L	A	-0.9112
19	R	A	-1.8791
20	L	A	0.0000
21	S	A	-0.2348
22	C	A	0.0000
23	A	A	-0.1471
24	A	A	0.0000
25	S	A	-0.8642
26	G	A	-1.2298
27	F	A	-0.4190
28	T	A	-0.1062
29	F	A	0.0000
30	S	A	-0.7883
31	S	A	-0.1441
32	Y	A	0.5120
33	G	A	-0.3900
34	M	A	0.0000
35	G	A	0.0000
36	W	A	0.0000
37	F	A	0.0839
38	R	A	0.0000
39	Q	A	-1.7592
40	A	A	-1.7954
41	P	A	-1.2883
42	G	A	-1.7231
43	K	A	-2.7646
44	G	A	-2.4205
45	R	A	-2.4253
46	E	A	-1.3378
47	L	A	0.1916
48	V	A	0.0000
49	A	A	0.0000
50	A	A	0.3867
51	I	A	0.0000
52	N	A	-0.9407
53	S	A	-0.9833
54	N	A	-1.8384
55	G	A	-1.5495
56	G	A	-1.2236
57	S	A	-0.6500
58	T	A	0.2247
59	Y	A	0.8694
60	Y	A	-0.2864
61	P	A	-1.1142
62	D	A	-2.4810
63	S	A	-1.8513
64	V	A	0.0000
65	E	A	-2.6230
66	G	A	-1.9661
67	R	A	-1.8870
68	F	A	0.0000
69	T	A	-0.8499
70	I	A	0.0000
71	S	A	-0.5283
72	R	A	-1.3209
73	D	A	-1.7042
74	N	A	-2.0120
75	A	A	-1.4916
76	K	A	-2.4416
77	R	A	-2.1495
78	M	A	-1.0114
79	V	A	0.0000
80	Y	A	-0.4701
81	L	A	0.0000
82	Q	A	-1.4028
83	M	A	0.0000
84	N	A	-2.0491
85	S	A	-1.4770
86	L	A	0.0000
87	R	A	-2.1267
88	A	A	-1.6156
89	E	A	-2.1696
90	D	A	0.0000
91	T	A	-0.8804
92	A	A	0.0000
93	V	A	-0.7255
94	Y	A	0.0000
95	Y	A	-0.0735
96	C	A	0.0000
97	A	A	0.0000
98	S	A	0.0000
99	G	A	-0.7904
100	D	A	-1.4209
101	Y	A	0.0365
102	W	A	0.3160
103	G	A	0.1639
104	Q	A	-0.8476
105	G	A	-0.4739
106	T	A	-0.7524
107	Q	A	-1.1031
108	V	A	0.0000
109	T	A	-0.3593
110	V	A	0.0000
111	S	A	-0.7669
112	S	A	-0.5313