Project name: 295

Chain sequence(s)	H: EVQLVESGGGVVQAGESLRLSCAASGRSFSDYEMGWFRQAPGTEREFVASINRRGSSTFYADSVKGRFTISRDNTKNTVYLQMSSLKPEDTAVYLCAAGWLFPSSRSRDYDYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:56)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:57)

• Minimal score value: -3.0757
• Maximal score value: 2.4726
• Average score: -0.7498
• Total score value: -92.2213

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.8316
2	V	H	0.0000
3	Q	H	-1.6326
4	L	H	0.0000
5	V	H	1.0582
6	E	H	0.1803
7	S	H	-0.3740
8	G	H	-0.8055
9	G	H	-0.4302
11	G	H	0.3571
12	V	H	1.2796
13	V	H	0.0000
14	Q	H	-1.6494
15	A	H	-1.8983
16	G	H	-1.8117
17	E	H	-2.1260
18	S	H	-1.2961
19	L	H	-0.5400
20	R	H	-0.9307
21	L	H	0.0000
22	S	H	-0.0544
23	C	H	0.0000
24	A	H	-0.1588
25	A	H	0.0000
26	S	H	-1.6603
27	G	H	-2.3316
28	R	H	-2.8410
29	S	H	-1.7888
30	F	H	0.0000
35	S	H	-2.3126
36	D	H	-2.1537
37	Y	H	0.0000
38	E	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.4226
45	A	H	-1.1530
46	P	H	-0.7906
47	G	H	-1.1126
48	T	H	-1.5921
49	E	H	-2.5192
50	R	H	-1.9956
51	E	H	-1.8555
52	F	H	-0.8079
53	V	H	0.0000
54	A	H	0.0000
55	S	H	0.0000
56	I	H	0.0000
57	N	H	-0.9081
58	R	H	-2.2361
59	R	H	-3.0757
62	G	H	-1.8402
63	S	H	-1.2002
64	S	H	-0.5164
65	T	H	0.2698
66	F	H	0.3277
67	Y	H	-0.5833
68	A	H	-1.2760
69	D	H	-2.4451
70	S	H	-1.6153
71	V	H	0.0000
72	K	H	-2.5436
74	G	H	-1.7194
75	R	H	-1.4062
76	F	H	0.0000
77	T	H	-0.5587
78	I	H	0.0000
79	S	H	-0.2717
80	R	H	-1.3594
81	D	H	-1.7560
82	N	H	-2.2158
83	T	H	-1.4230
84	K	H	-2.3427
85	N	H	-2.0060
86	T	H	-0.9329
87	V	H	0.0000
88	Y	H	-0.1055
89	L	H	0.0000
90	Q	H	-0.5542
91	M	H	0.0000
92	S	H	-1.0973
93	S	H	-1.3292
94	L	H	0.0000
95	K	H	-2.1987
96	P	H	-1.6542
97	E	H	-1.8688
98	D	H	0.0000
99	T	H	-0.6493
100	A	H	0.0000
101	V	H	-0.2111
102	Y	H	0.0000
103	L	H	-0.1344
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	G	H	0.0000
108	W	H	1.6139
109	L	H	2.4726
110	F	H	2.0843
111	P	H	1.1024
111A	S	H	0.0120
112B	S	H	-1.0313
112A	R	H	-2.2642
112	S	H	-2.1994
113	R	H	-2.6493
114	D	H	-1.6413
115	Y	H	0.0000
116	D	H	-0.9961
117	Y	H	-0.8234
118	W	H	-0.0925
119	G	H	-0.1991
120	Q	H	-0.9662
121	G	H	-0.4585
122	T	H	-0.4848
123	Q	H	-0.6402
124	V	H	0.0000
125	T	H	-0.0627
126	V	H	0.0000
127	S	H	-0.7065
128	S	H	-0.8528