Project name: 49f92401207be81

Chain sequence(s)	A: EQAALIAEAERIAARVRANMAEAEAVIREGDAASQAHLPAFRAQAAELDALTAELLAALRAEDWEAAAATLRRLLAAGEEYIAIMEKAKVPQELIDRARQIRAEGERLLEKLAAAVAAHS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:01)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:01)

• Minimal score value: -3.6933
• Maximal score value: 0.0
• Average score: -1.5532
• Total score value: -186.3805

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.0887
2	Q	A	-2.0402
3	A	A	-1.1243
4	A	A	-0.8947
5	L	A	0.0000
6	I	A	-1.4816
7	A	A	-1.2975
8	E	A	-1.9496
9	A	A	0.0000
10	E	A	-2.7044
11	R	A	-2.9419
12	I	A	-1.8533
13	A	A	-1.6587
14	A	A	-1.5075
15	R	A	-1.5019
16	V	A	-1.2638
17	R	A	-1.0223
18	A	A	-0.8020
19	N	A	0.0000
20	M	A	0.0000
21	A	A	-0.9146
22	E	A	-1.6957
23	A	A	0.0000
24	E	A	-1.8968
25	A	A	-1.5193
26	V	A	-1.6148
27	I	A	0.0000
28	R	A	-3.2259
29	E	A	-3.1898
30	G	A	-2.8862
31	D	A	-2.9055
32	A	A	-1.6359
33	A	A	-1.2340
34	S	A	-2.4707
35	Q	A	-2.4943
36	A	A	-1.1337
37	H	A	-1.4346
38	L	A	-1.2051
39	P	A	-0.9744
40	A	A	-0.8094
41	F	A	0.0000
42	R	A	-2.1311
43	A	A	-1.3876
44	Q	A	-1.6270
45	A	A	-1.6086
46	A	A	-1.6109
47	E	A	-2.2155
48	L	A	0.0000
49	D	A	-2.1550
50	A	A	-1.5726
51	L	A	0.0000
52	T	A	-1.5399
53	A	A	-1.4153
54	E	A	-2.0628
55	L	A	0.0000
56	L	A	-1.1997
57	A	A	-1.4560
58	A	A	-2.0414
59	L	A	0.0000
60	R	A	-2.6927
61	A	A	-2.0674
62	E	A	-3.4140
63	D	A	-2.9323
64	W	A	0.0000
65	E	A	-2.3720
66	A	A	-1.8243
67	A	A	0.0000
68	A	A	-1.7164
69	A	A	-1.4670
70	T	A	-1.7804
71	L	A	0.0000
72	R	A	-2.7813
73	R	A	-2.7716
74	L	A	-2.4276
75	L	A	0.0000
76	A	A	-2.0238
77	A	A	0.0000
78	G	A	-2.3268
79	E	A	-2.8014
80	E	A	-2.5753
81	Y	A	0.0000
82	I	A	0.0000
83	A	A	-2.1401
84	I	A	-2.0504
85	M	A	0.0000
86	E	A	-3.4931
87	K	A	-2.9995
88	A	A	0.0000
89	K	A	-3.2888
90	V	A	0.0000
91	P	A	-2.1849
92	Q	A	-3.1905
93	E	A	-3.3255
94	L	A	0.0000
95	I	A	0.0000
96	D	A	-3.6536
97	R	A	-3.1568
98	A	A	0.0000
99	R	A	-3.6933
100	Q	A	-2.8079
101	I	A	0.0000
102	R	A	-2.5388
103	A	A	-2.2133
104	E	A	-2.4784
105	G	A	0.0000
106	E	A	-3.1706
107	R	A	-3.4809
108	L	A	0.0000
109	L	A	-2.4803
110	E	A	-3.1726
111	K	A	-2.4333
112	L	A	0.0000
113	A	A	-1.1780
114	A	A	-0.7258
115	A	A	-1.3816
116	V	A	-1.0240
117	A	A	-0.3703
118	A	A	-0.2857
119	H	A	-1.3811
120	S	A	-0.7106