Project name: 4a3033c8cc24ecb

Chain sequence(s)	H: PLVLQESGPGLVKPSEALSLTCTVSGDSINTILYYWSWIRQPPGKGLEWIGYIYYSGSTYGNPSLKSRVTISVNTSKNQFYSKLSSVTAADTAVYYCARVPLVVNPWGQGTLVTVSS; L: PSALTQPPSASGSLGQSVTISCTGTSSDVGGYNYVSWYQQHAGKAPKVIIYEVNKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYEGSDNFVFGTGTKVTVL
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:17)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:19)

• Minimal score value: -2.3548
• Maximal score value: 2.7137
• Average score: -0.3809
• Total score value: -86.4605

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	P	H	-0.0287
2	L	H	0.4400
3	V	H	1.1795
4	L	H	0.0000
5	Q	H	-0.6906
6	E	H	0.0000
7	S	H	-0.7053
8	G	H	-0.4846
9	P	H	-0.1204
11	G	H	0.2079
12	L	H	0.7778
13	V	H	0.0000
14	K	H	-1.3731
15	P	H	-1.1451
16	S	H	-1.3174
17	E	H	-1.9443
18	A	H	-1.2210
19	L	H	0.0000
20	S	H	-0.7925
21	L	H	0.0000
22	T	H	-0.4026
23	C	H	0.0000
24	T	H	-0.4988
25	V	H	0.0000
26	S	H	-0.2843
27	G	H	-0.3893
28	D	H	-0.6611
29	S	H	-0.7591
30	I	H	0.0000
31	N	H	-0.1468
34	T	H	1.0629
35	I	H	2.7137
36	L	H	2.6458
37	Y	H	1.7323
38	Y	H	1.3118
39	W	H	0.0000
40	S	H	0.0000
41	W	H	0.0000
42	I	H	0.0000
43	R	H	0.0000
44	Q	H	-0.6588
45	P	H	-0.8043
46	P	H	-0.9658
47	G	H	-1.4563
48	K	H	-2.1673
49	G	H	-1.3009
50	L	H	0.0000
51	E	H	-0.6661
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	Y	H	0.0000
56	I	H	0.0000
57	Y	H	0.8264
58	Y	H	0.3798
59	S	H	-0.0732
63	G	H	-0.4594
64	S	H	-0.1664
65	T	H	0.0603
66	Y	H	0.0939
67	G	H	0.0000
68	N	H	0.0000
69	P	H	-0.8779
70	S	H	-0.8290
71	L	H	0.0000
72	K	H	-1.5581
74	S	H	-1.0651
75	R	H	-1.0312
76	V	H	-0.7949
77	T	H	-0.5567
78	I	H	0.0000
79	S	H	-0.1854
80	V	H	-0.3657
81	N	H	-1.1002
82	T	H	-1.1037
83	S	H	-1.3658
84	K	H	-2.1036
85	N	H	-1.5791
86	Q	H	-1.0885
87	F	H	0.0000
88	Y	H	-0.0695
89	S	H	0.0000
90	K	H	-0.9189
91	L	H	0.0000
92	S	H	-0.9169
93	S	H	-0.9875
94	V	H	0.0000
95	T	H	-0.5670
96	A	H	-0.1833
97	A	H	0.0372
98	D	H	0.0000
99	T	H	0.2339
100	A	H	0.0000
101	V	H	0.3414
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	R	H	0.2541
107	V	H	0.0000
108	P	H	0.6271
109	L	H	0.9197
114	V	H	0.0000
115	V	H	0.0000
116	N	H	-0.3744
117	P	H	-0.2283
118	W	H	0.0000
119	G	H	0.0000
120	Q	H	-1.5115
121	G	H	0.0000
122	T	H	-0.1355
123	L	H	0.6888
124	V	H	0.0000
125	T	H	0.3469
126	V	H	0.0000
127	S	H	-0.3293
128	S	H	-0.5078
1	P	L	-0.4941
2	S	L	-0.3692
3	A	L	-0.2004
4	L	L	0.0000
5	T	L	-0.2121
6	Q	L	0.0000
7	P	L	-0.4227
8	P	L	-0.6615
9	S	L	-0.7514
11	A	L	-0.4677
12	S	L	0.0496
13	G	L	0.1613
14	S	L	0.6741
15	L	L	1.0637
16	G	L	-0.4304
17	Q	L	-1.0515
18	S	L	-0.7729
19	V	L	-0.3792
20	T	L	-0.1333
21	I	L	0.0000
22	S	L	-0.2280
23	C	L	0.0000
24	T	L	-0.4750
25	G	L	-0.6008
26	T	L	-0.6929
27	S	L	-0.8395
28	S	L	-0.6655
29	D	L	0.0000
30	V	L	0.0000
31	G	L	-1.1338
35	G	L	-0.8980
36	Y	L	-0.4597
37	N	L	-1.0948
38	Y	L	0.1586
39	V	L	0.0000
40	S	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	0.0000
45	H	L	-1.6023
46	A	L	-1.0856
47	G	L	-1.4532
48	K	L	-2.3548
49	A	L	-1.4745
50	P	L	0.0000
51	K	L	-1.1059
52	V	L	0.0000
53	I	L	0.0000
54	I	L	0.0000
55	Y	L	-0.7118
56	E	L	-0.9951
57	V	L	-1.2077
65	N	L	-2.1940
66	K	L	-2.2905
67	R	L	-2.3243
68	P	L	-1.1735
69	S	L	-0.8037
70	G	L	-0.9180
71	V	L	-1.1524
72	P	L	-1.3684
74	D	L	-2.3421
75	R	L	-1.4494
76	F	L	0.0000
77	S	L	-1.4079
78	G	L	-1.2200
79	S	L	-1.1113
80	K	L	-1.2417
83	S	L	-0.8407
84	G	L	-1.1102
85	N	L	-1.1654
86	T	L	-0.7698
87	A	L	0.0000
88	S	L	-0.4480
89	L	L	0.0000
90	T	L	-0.3457
91	V	L	0.0000
92	S	L	-0.9846
93	G	L	-0.9759
94	L	L	0.0000
95	Q	L	-0.9990
96	A	L	-0.7178
97	E	L	-1.9705
98	D	L	0.0000
99	E	L	-1.6146
100	A	L	0.0000
101	D	L	-1.2186
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	S	L	0.0000
106	S	L	0.0000
107	Y	L	0.0602
108	E	L	-0.4481
109	G	L	-0.5699
113	S	L	-0.4760
114	D	L	-0.4736
115	N	L	0.0000
116	F	L	0.1083
117	V	L	0.0000
118	F	L	0.0000
119	G	L	0.0000
120	T	L	-0.5918
121	G	L	0.0000
122	T	L	0.0000
123	K	L	-1.2939
124	V	L	0.0000
125	T	L	-0.1944
126	V	L	0.4097
127	L	L	1.6221