| Chain sequence(s) |
A: MTSLFAAIQPYKTHLLRVSPLHRLSIKEYGNPQGKPVVFLHGGPGGGASDSDARRFNPTTYRIVLFDQRGSGESTPASCLEDNTTQALVEDIEKIREFLQVGAAWHVFGGSWGSTLALAYAQAHPARVKSLTLRGIFTLRKKELDFFYQGPGSSRKFPAYWAEYLDPIPVAERGDMVKAYYERLTGSDEKVRAEAGRAWSRWEMATSRLHVDPDYISKADAPGFADAFARIESHYFVNGGFMPEGELLKPENIAKISHIPAVIVQGAYDMVCPITTAYELTALWPEAKFVVIPDAGHSAIEAGTEKALVEATEEFAKLA
B: MTSLFAAIQPYKTHLLRVSPLHRLSIKEYGNPQGKPVVFLHGGPGGGASDSDARRFNPTTYRIVLFDQRGSGESTPASCLEDNTTQALVEDIEKIREFLQVGAAWHVFGGSWGSTLALAYAQAHPARVKSLTLRGIFTLRKKELDFFYQGPGSSRKFPAYWAEYLDPIPVAERGDMVKAYYERLTGSDEKVRAEAGRAWSRWEMATSRLHVDPDYISKADAPGFADAFARIESHYFVNGGFMPEGELLKPENIAKISHIPAVIVQGAYDMVCPITTAYELTALWPEAKFVVIPDAGHSAIEAGTEKALVEATEEFAKLA input PDB |
| Selected Chain(s) | A,B |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | AG267B,AG159B,AG162B,AG159A,AG162A,AG282A,AG282B,AG267A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 7.43084 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:01)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:01)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:01)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:01)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:01)
[INFO] FoldX: Building mutant model (00:06:11)
[INFO] FoldX: Starting FoldX energy minimalization (00:07:06)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:13:11)
[INFO] Main: Simulation completed successfully. (00:13:19)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | 0.9399 | |
| 2 | T | A | 0.4516 | |
| 3 | S | A | -0.3198 | |
| 4 | L | A | 0.1888 | |
| 5 | F | A | 0.3240 | |
| 6 | A | A | 0.1163 | |
| 7 | A | A | -0.1787 | |
| 8 | I | A | -0.4289 | |
| 9 | Q | A | -1.3804 | |
| 10 | P | A | -1.0001 | |
| 11 | Y | A | -0.5013 | |
| 12 | K | A | -1.4444 | |
| 13 | T | A | -0.5472 | |
| 14 | H | A | -0.0180 | |
| 15 | L | A | 0.5950 | |
| 16 | L | A | -0.2517 | |
| 17 | R | A | -1.8315 | |
| 18 | V | A | 0.0000 | |
| 19 | S | A | -0.8126 | |
| 20 | P | A | -0.4271 | |
| 21 | L | A | -0.4640 | |
| 22 | H | A | 0.0000 | |
| 23 | R | A | -1.4129 | |
| 24 | L | A | 0.0000 | |
| 25 | S | A | 0.0000 | |
| 26 | I | A | 0.0000 | |
| 27 | K | A | -0.9261 | |
| 28 | E | A | 0.0000 | |
| 29 | Y | A | 0.0000 | |
| 30 | G | A | -0.8175 | |
| 31 | N | A | -1.0179 | |
| 32 | P | A | -1.2122 | |
| 33 | Q | A | -1.6181 | |
| 34 | G | A | -1.2036 | |
| 35 | K | A | -1.1534 | |
| 36 | P | A | -0.8721 | |
| 37 | V | A | 0.0000 | |
| 38 | V | A | 0.0000 | |
| 39 | F | A | 0.0000 | |
| 40 | L | A | 0.0000 | |
| 41 | H | A | 0.0000 | |
| 42 | G | A | -0.1717 | |
| 43 | G | A | 0.0000 | |
| 44 | P | A | 0.0000 | |
| 45 | G | A | 0.0000 | |
| 46 | G | A | -0.2277 | |
| 47 | G | A | -0.6450 | |
| 48 | A | A | -0.7688 | |
| 49 | S | A | -0.7932 | |
| 50 | D | A | -1.2411 | |
| 51 | S | A | -0.8021 | |
| 52 | D | A | -0.5587 | |
| 53 | A | A | 0.0000 | |
| 54 | R | A | -0.5452 | |
| 55 | R | A | 0.0000 | |
| 56 | F | A | 0.0000 | |
| 57 | N | A | -0.4677 | |
| 58 | P | A | -0.3566 | |
| 59 | T | A | -0.5874 | |
| 60 | T | A | -0.9283 | |
| 61 | Y | A | 0.0000 | |
| 62 | R | A | -0.9656 | |
| 63 | I | A | 0.0000 | |
| 64 | V | A | 0.0000 | |
| 65 | L | A | 0.0000 | |
| 66 | F | A | 0.0000 | |
| 67 | D | A | 0.0000 | |
| 68 | Q | A | 0.0000 | |
| 69 | R | A | 0.0000 | |
| 70 | G | A | 0.0000 | |
| 71 | S | A | 0.0000 | |
| 72 | G | A | -1.3986 | |
| 73 | E | A | -1.9964 | |
| 74 | S | A | 0.0000 | |
| 75 | T | A | -0.8016 | |
| 76 | P | A | -0.5718 | |
| 77 | A | A | -0.5337 | |
| 78 | S | A | -0.3226 | |
| 79 | C | A | -0.5580 | |
| 80 | L | A | -1.0884 | |
| 81 | E | A | -2.3140 | |
| 82 | D | A | -2.2886 | |
| 83 | N | A | 0.0000 | |
| 84 | T | A | -0.9620 | |
| 85 | T | A | 0.0000 | |
| 86 | Q | A | -1.5543 | |
| 87 | A | A | 0.0000 | |
| 88 | L | A | 0.0000 | |
| 89 | V | A | 0.0000 | |
| 90 | E | A | -2.3081 | |
| 91 | D | A | 0.0000 | |
| 92 | I | A | 0.0000 | |
| 93 | E | A | -1.6642 | |
| 94 | K | A | -1.9871 | |
| 95 | I | A | 0.0000 | |
| 96 | R | A | 0.0000 | |
| 97 | E | A | -2.1920 | |
| 98 | F | A | -0.5802 | |
| 99 | L | A | 0.0000 | |
| 100 | Q | A | -1.7596 | |
| 101 | V | A | 0.0000 | |
| 102 | G | A | -1.2317 | |
| 103 | A | A | -0.7897 | |
| 104 | A | A | -0.6121 | |
| 105 | W | A | 0.0000 | |
| 106 | H | A | 0.0000 | |
| 107 | V | A | 0.0000 | |
| 108 | F | A | 0.0000 | |
| 109 | G | A | 0.0000 | |
| 110 | G | A | 0.0000 | |
| 111 | S | A | 0.0000 | |
| 112 | W | A | 0.0000 | |
| 113 | G | A | 0.0000 | |
| 114 | S | A | 0.0000 | |
| 115 | T | A | 0.0000 | |
| 116 | L | A | 0.0000 | |
| 117 | A | A | 0.0000 | |
| 118 | L | A | 0.0000 | |
| 119 | A | A | -0.2369 | |
| 120 | Y | A | 0.0000 | |
| 121 | A | A | 0.0000 | |
| 122 | Q | A | 0.0000 | |
| 123 | A | A | -0.6387 | |
| 124 | H | A | -0.8012 | |
| 125 | P | A | -0.8180 | |
| 126 | A | A | -0.5566 | |
| 127 | R | A | -0.8877 | |
| 128 | V | A | 0.0000 | |
| 129 | K | A | -0.8116 | |
| 130 | S | A | 0.0000 | |
| 131 | L | A | 0.0000 | |
| 132 | T | A | 0.0000 | |
| 133 | L | A | 0.0000 | |
| 134 | R | A | -0.0903 | |
| 135 | G | A | 0.0000 | |
| 136 | I | A | 0.0000 | |
| 137 | F | A | 0.0000 | |
| 138 | T | A | 0.0000 | |
| 139 | L | A | 0.0000 | |
| 140 | R | A | 0.0000 | |
| 141 | K | A | -2.8914 | |
| 142 | K | A | -2.6813 | |
| 143 | E | A | 0.0000 | |
| 144 | L | A | 0.0000 | |
| 145 | D | A | -1.8877 | |
| 146 | F | A | 0.0000 | |
| 147 | F | A | 0.0000 | |
| 148 | Y | A | 0.0000 | |
| 149 | Q | A | -1.2139 | |
| 150 | G | A | -0.7198 | |
| 151 | P | A | -0.6730 | |
| 152 | G | A | 0.0000 | |
| 153 | S | A | 0.0000 | |
| 154 | S | A | 0.0000 | |
| 155 | R | A | -0.3601 | |
| 156 | K | A | 0.0000 | |
| 157 | F | A | 0.0000 | |
| 158 | P | A | -0.2755 | |
| 159 | G | A | -0.4061 | mutated: AG159A |
| 160 | Y | A | -0.3518 | |
| 161 | W | A | -0.5152 | |
| 162 | G | A | -0.9926 | mutated: AG162A |
| 163 | E | A | -1.4925 | |
| 164 | Y | A | 0.0000 | |
| 165 | L | A | -0.8179 | |
| 166 | D | A | -1.8527 | |
| 167 | P | A | -1.0886 | |
| 168 | I | A | 0.0000 | |
| 169 | P | A | -0.0130 | |
| 170 | V | A | 0.9812 | |
| 171 | A | A | 0.0125 | |
| 172 | E | A | -1.2472 | |
| 173 | R | A | -1.3849 | |
| 174 | G | A | -1.6051 | |
| 175 | D | A | -2.4647 | |
| 176 | M | A | 0.0000 | |
| 177 | V | A | -1.0714 | |
| 178 | K | A | -1.8334 | |
| 179 | A | A | 0.0000 | |
| 180 | Y | A | 0.0000 | |
| 181 | Y | A | -1.0424 | |
| 182 | E | A | -2.2207 | |
| 183 | R | A | -2.1870 | |
| 184 | L | A | 0.0000 | |
| 185 | T | A | -1.2992 | |
| 186 | G | A | -1.8991 | |
| 187 | S | A | -2.0009 | |
| 188 | D | A | -3.0292 | |
| 189 | E | A | -3.6785 | |
| 190 | K | A | -3.3455 | |
| 191 | V | A | -2.1257 | |
| 192 | R | A | -2.8381 | |
| 193 | A | A | -2.7564 | |
| 194 | E | A | -3.0205 | |
| 195 | A | A | 0.0000 | |
| 196 | G | A | 0.0000 | |
| 197 | R | A | -2.4138 | |
| 198 | A | A | -1.7272 | |
| 199 | W | A | 0.0000 | |
| 200 | S | A | 0.0000 | |
| 201 | R | A | -1.0834 | |
| 202 | W | A | 0.0000 | |
| 203 | E | A | 0.0000 | |
| 204 | M | A | 0.0000 | |
| 205 | A | A | 0.0000 | |
| 206 | T | A | 0.0000 | |
| 207 | S | A | 0.0000 | |
| 208 | R | A | -0.6051 | |
| 209 | L | A | -1.0894 | |
| 210 | H | A | -1.4649 | |
| 211 | V | A | -0.5392 | |
| 212 | D | A | -1.0386 | |
| 213 | P | A | -1.2765 | |
| 214 | D | A | -2.0170 | |
| 215 | Y | A | -1.2401 | |
| 216 | I | A | -1.1863 | |
| 217 | S | A | -1.8255 | |
| 218 | K | A | -1.9374 | |
| 219 | A | A | 0.0000 | |
| 220 | D | A | -2.5540 | |
| 221 | A | A | -1.4082 | |
| 222 | P | A | -1.4320 | |
| 223 | G | A | -0.7884 | |
| 224 | F | A | -0.5770 | |
| 225 | A | A | 0.0000 | |
| 226 | D | A | -0.9228 | |
| 227 | A | A | 0.0000 | |
| 228 | F | A | 0.0000 | |
| 229 | A | A | 0.0000 | |
| 230 | R | A | -0.5046 | |
| 231 | I | A | 0.0000 | |
| 232 | E | A | 0.0000 | |
| 233 | S | A | 0.0000 | |
| 234 | H | A | -0.3601 | |
| 235 | Y | A | 0.0000 | |
| 236 | F | A | 0.0000 | |
| 237 | V | A | -0.3730 | |
| 238 | N | A | -0.6250 | |
| 239 | G | A | -1.0132 | |
| 240 | G | A | 0.0000 | |
| 241 | F | A | -0.2762 | |
| 242 | M | A | -0.6822 | |
| 243 | P | A | -1.2852 | |
| 244 | E | A | -2.6609 | |
| 245 | G | A | -1.8243 | |
| 246 | E | A | -1.6005 | |
| 247 | L | A | 0.0000 | |
| 248 | L | A | 0.0000 | |
| 249 | K | A | -1.7713 | |
| 250 | P | A | -1.5502 | |
| 251 | E | A | -2.4592 | |
| 252 | N | A | 0.0000 | |
| 253 | I | A | 0.0000 | |
| 254 | A | A | -1.3119 | |
| 255 | K | A | -1.6528 | |
| 256 | I | A | 0.0000 | |
| 257 | S | A | -1.2177 | |
| 258 | H | A | -1.5784 | |
| 259 | I | A | 0.0000 | |
| 260 | P | A | -0.9637 | |
| 261 | A | A | 0.0000 | |
| 262 | V | A | 0.0000 | |
| 263 | I | A | 0.0000 | |
| 264 | V | A | 0.0000 | |
| 265 | Q | A | 0.0000 | |
| 266 | G | A | 0.0000 | |
| 267 | G | A | -0.2273 | mutated: AG267A |
| 268 | Y | A | 0.0000 | |
| 269 | D | A | 0.0000 | |
| 270 | M | A | 0.0000 | |
| 271 | V | A | 0.0000 | |
| 272 | C | A | 0.0000 | |
| 273 | P | A | 0.0000 | |
| 274 | I | A | 0.0000 | |
| 275 | T | A | -0.2042 | |
| 276 | T | A | 0.0000 | |
| 277 | A | A | 0.0000 | |
| 278 | Y | A | 0.1714 | |
| 279 | E | A | -0.7323 | |
| 280 | L | A | 0.0000 | |
| 281 | T | A | -0.5642 | |
| 282 | G | A | -0.5971 | mutated: AG282A |
| 283 | L | A | -0.1502 | |
| 284 | W | A | 0.0000 | |
| 285 | P | A | -1.2401 | |
| 286 | E | A | -2.3524 | |
| 287 | A | A | 0.0000 | |
| 288 | K | A | -1.3247 | |
| 289 | F | A | 0.1422 | |
| 290 | V | A | 0.6850 | |
| 291 | V | A | 0.8771 | |
| 292 | I | A | 0.0000 | |
| 293 | P | A | -0.5539 | |
| 294 | D | A | -1.7084 | |
| 295 | A | A | 0.0000 | |
| 296 | G | A | 0.0000 | |
| 297 | H | A | 0.0000 | |
| 298 | S | A | 0.0000 | |
| 299 | A | A | 0.0799 | |
| 300 | I | A | 0.5431 | |
| 301 | E | A | 0.0000 | |
| 302 | A | A | -0.1740 | |
| 303 | G | A | -0.5509 | |
| 304 | T | A | 0.0000 | |
| 305 | E | A | -0.7249 | |
| 306 | K | A | -1.5033 | |
| 307 | A | A | -1.2292 | |
| 308 | L | A | 0.0000 | |
| 309 | V | A | 0.0000 | |
| 310 | E | A | -2.7038 | |
| 311 | A | A | 0.0000 | |
| 312 | T | A | 0.0000 | |
| 313 | E | A | -2.2658 | |
| 314 | E | A | -2.4017 | |
| 315 | F | A | 0.0000 | |
| 316 | A | A | -1.6195 | |
| 317 | K | A | -2.0533 | |
| 318 | L | A | -0.9101 | |
| 319 | A | A | -0.3397 | |
| 1 | M | B | 0.9327 | |
| 2 | T | B | 0.4491 | |
| 3 | S | B | -0.2995 | |
| 4 | L | B | 0.1736 | |
| 5 | F | B | 0.3323 | |
| 6 | A | B | 0.1256 | |
| 7 | A | B | -0.1681 | |
| 8 | I | B | -0.4000 | |
| 9 | Q | B | -1.3147 | |
| 10 | P | B | -0.8698 | |
| 11 | Y | B | -0.3046 | |
| 12 | K | B | -1.1310 | |
| 13 | T | B | -0.4128 | |
| 14 | H | B | 0.0043 | |
| 15 | L | B | 0.5580 | |
| 16 | L | B | -0.2638 | |
| 17 | R | B | -1.8237 | |
| 18 | V | B | 0.0000 | |
| 19 | S | B | -0.8036 | |
| 20 | P | B | -0.4303 | |
| 21 | L | B | -0.4691 | |
| 22 | H | B | 0.0000 | |
| 23 | R | B | -1.3886 | |
| 24 | L | B | 0.0000 | |
| 25 | S | B | 0.0000 | |
| 26 | I | B | 0.0000 | |
| 27 | K | B | -0.8237 | |
| 28 | E | B | 0.0000 | |
| 29 | Y | B | 0.0000 | |
| 30 | G | B | -0.7533 | |
| 31 | N | B | -0.9689 | |
| 32 | P | B | -1.0764 | |
| 33 | Q | B | -1.5580 | |
| 34 | G | B | -1.1512 | |
| 35 | K | B | -1.0606 | |
| 36 | P | B | -0.7561 | |
| 37 | V | B | 0.0000 | |
| 38 | V | B | 0.0000 | |
| 39 | F | B | 0.0000 | |
| 40 | L | B | 0.0000 | |
| 41 | H | B | 0.0000 | |
| 42 | G | B | -0.1673 | |
| 43 | G | B | 0.0000 | |
| 44 | P | B | 0.0000 | |
| 45 | G | B | 0.0000 | |
| 46 | G | B | -0.2024 | |
| 47 | G | B | -0.6305 | |
| 48 | A | B | -0.7645 | |
| 49 | S | B | -0.7844 | |
| 50 | D | B | -1.2203 | |
| 51 | S | B | -0.7930 | |
| 52 | D | B | -0.5960 | |
| 53 | A | B | 0.0000 | |
| 54 | R | B | -0.5301 | |
| 55 | R | B | 0.0000 | |
| 56 | F | B | 0.0000 | |
| 57 | N | B | -0.4677 | |
| 58 | P | B | -0.3328 | |
| 59 | T | B | -0.5736 | |
| 60 | T | B | -0.9185 | |
| 61 | Y | B | 0.0000 | |
| 62 | R | B | -0.8851 | |
| 63 | I | B | 0.0000 | |
| 64 | V | B | 0.0000 | |
| 65 | L | B | 0.0000 | |
| 66 | F | B | 0.0000 | |
| 67 | D | B | 0.0000 | |
| 68 | Q | B | 0.0000 | |
| 69 | R | B | 0.0000 | |
| 70 | G | B | 0.0000 | |
| 71 | S | B | 0.0000 | |
| 72 | G | B | -1.3879 | |
| 73 | E | B | -1.9971 | |
| 74 | S | B | 0.0000 | |
| 75 | T | B | -0.7930 | |
| 76 | P | B | -0.5646 | |
| 77 | A | B | -0.5159 | |
| 78 | S | B | 0.0000 | |
| 79 | C | B | -0.5433 | |
| 80 | L | B | -1.0748 | |
| 81 | E | B | -2.2976 | |
| 82 | D | B | -2.2559 | |
| 83 | N | B | 0.0000 | |
| 84 | T | B | -0.9411 | |
| 85 | T | B | 0.0000 | |
| 86 | Q | B | -1.5686 | |
| 87 | A | B | 0.0000 | |
| 88 | L | B | 0.0000 | |
| 89 | V | B | 0.0000 | |
| 90 | E | B | -2.3758 | |
| 91 | D | B | 0.0000 | |
| 92 | I | B | 0.0000 | |
| 93 | E | B | -1.6787 | |
| 94 | K | B | -1.9842 | |
| 95 | I | B | 0.0000 | |
| 96 | R | B | 0.0000 | |
| 97 | E | B | -2.1441 | |
| 98 | F | B | -0.5734 | |
| 99 | L | B | 0.0000 | |
| 100 | Q | B | -1.6665 | |
| 101 | V | B | -1.0807 | |
| 102 | G | B | -1.1219 | |
| 103 | A | B | -0.7219 | |
| 104 | A | B | -0.5141 | |
| 105 | W | B | 0.0000 | |
| 106 | H | B | 0.0000 | |
| 107 | V | B | 0.0000 | |
| 108 | F | B | 0.0000 | |
| 109 | G | B | 0.0000 | |
| 110 | G | B | 0.0000 | |
| 111 | S | B | 0.0000 | |
| 112 | W | B | 0.0000 | |
| 113 | G | B | 0.0000 | |
| 114 | S | B | 0.0000 | |
| 115 | T | B | 0.0000 | |
| 116 | L | B | 0.0000 | |
| 117 | A | B | 0.0000 | |
| 118 | L | B | 0.0000 | |
| 119 | A | B | -0.2388 | |
| 120 | Y | B | 0.0000 | |
| 121 | A | B | 0.0000 | |
| 122 | Q | B | 0.0000 | |
| 123 | A | B | -0.6534 | |
| 124 | H | B | -0.8161 | |
| 125 | P | B | -0.7972 | |
| 126 | A | B | -0.5253 | |
| 127 | R | B | -0.8408 | |
| 128 | V | B | 0.0000 | |
| 129 | K | B | -0.5846 | |
| 130 | S | B | 0.0000 | |
| 131 | L | B | 0.0000 | |
| 132 | T | B | 0.0000 | |
| 133 | L | B | 0.0000 | |
| 134 | R | B | -0.0772 | |
| 135 | G | B | 0.0000 | |
| 136 | I | B | 0.0000 | |
| 137 | F | B | 0.0000 | |
| 138 | T | B | 0.0000 | |
| 139 | L | B | 0.0000 | |
| 140 | R | B | 0.0000 | |
| 141 | K | B | -2.7928 | |
| 142 | K | B | -2.5071 | |
| 143 | E | B | 0.0000 | |
| 144 | L | B | 0.0000 | |
| 145 | D | B | -1.7904 | |
| 146 | F | B | 0.0000 | |
| 147 | F | B | 0.0000 | |
| 148 | Y | B | 0.0000 | |
| 149 | Q | B | -1.1776 | |
| 150 | G | B | -0.6890 | |
| 151 | P | B | -0.6939 | |
| 152 | G | B | 0.0000 | |
| 153 | S | B | 0.0000 | |
| 154 | S | B | 0.0000 | |
| 155 | R | B | -0.2497 | |
| 156 | K | B | 0.0000 | |
| 157 | F | B | 0.0000 | |
| 158 | P | B | -0.3373 | |
| 159 | G | B | -0.4954 | mutated: AG159B |
| 160 | Y | B | -0.4337 | |
| 161 | W | B | -0.5674 | |
| 162 | G | B | -1.0477 | mutated: AG162B |
| 163 | E | B | -1.5673 | |
| 164 | Y | B | 0.0000 | |
| 165 | L | B | -0.8418 | |
| 166 | D | B | -1.8756 | |
| 167 | P | B | -1.1437 | |
| 168 | I | B | 0.0000 | |
| 169 | P | B | -0.0633 | |
| 170 | V | B | 0.9766 | |
| 171 | A | B | 0.0082 | |
| 172 | E | B | -1.2515 | |
| 173 | R | B | -1.3996 | |
| 174 | G | B | -1.6250 | |
| 175 | D | B | -2.4630 | |
| 176 | M | B | 0.0000 | |
| 177 | V | B | -1.0609 | |
| 178 | K | B | -1.8297 | |
| 179 | A | B | 0.0000 | |
| 180 | Y | B | 0.0000 | |
| 181 | Y | B | -1.0455 | |
| 182 | E | B | -2.2268 | |
| 183 | R | B | -2.1763 | |
| 184 | L | B | 0.0000 | |
| 185 | T | B | -1.2916 | |
| 186 | G | B | -1.8782 | |
| 187 | S | B | -1.9668 | |
| 188 | D | B | -2.9592 | |
| 189 | E | B | -3.6466 | |
| 190 | K | B | -3.3124 | |
| 191 | V | B | -2.0729 | |
| 192 | R | B | -2.8405 | |
| 193 | A | B | -2.7591 | |
| 194 | E | B | -3.0229 | |
| 195 | A | B | 0.0000 | |
| 196 | G | B | 0.0000 | |
| 197 | R | B | -2.4222 | |
| 198 | A | B | -1.7409 | |
| 199 | W | B | 0.0000 | |
| 200 | S | B | 0.0000 | |
| 201 | R | B | -1.0801 | |
| 202 | W | B | 0.0000 | |
| 203 | E | B | 0.0000 | |
| 204 | M | B | 0.0000 | |
| 205 | A | B | 0.0000 | |
| 206 | T | B | 0.0000 | |
| 207 | S | B | 0.0000 | |
| 208 | R | B | -0.4529 | |
| 209 | L | B | -0.8852 | |
| 210 | H | B | -0.9795 | |
| 211 | V | B | -0.0378 | |
| 212 | D | B | -0.7913 | |
| 213 | P | B | -1.1671 | |
| 214 | D | B | -1.9725 | |
| 215 | Y | B | -1.1681 | |
| 216 | I | B | -1.1445 | |
| 217 | S | B | -1.8367 | |
| 218 | K | B | -1.9249 | |
| 219 | A | B | 0.0000 | |
| 220 | D | B | -2.5804 | |
| 221 | A | B | -1.4121 | |
| 222 | P | B | -1.4323 | |
| 223 | G | B | -0.7732 | |
| 224 | F | B | -0.5427 | |
| 225 | A | B | 0.0000 | |
| 226 | D | B | -0.9208 | |
| 227 | A | B | 0.0000 | |
| 228 | F | B | 0.0000 | |
| 229 | A | B | 0.0000 | |
| 230 | R | B | -0.5011 | |
| 231 | I | B | 0.0000 | |
| 232 | E | B | 0.0000 | |
| 233 | S | B | 0.0000 | |
| 234 | H | B | -0.3379 | |
| 235 | Y | B | 0.0000 | |
| 236 | F | B | 0.0000 | |
| 237 | V | B | -0.3317 | |
| 238 | N | B | -0.5411 | |
| 239 | G | B | -0.9699 | |
| 240 | G | B | 0.0000 | |
| 241 | F | B | -0.2379 | |
| 242 | M | B | -0.6674 | |
| 243 | P | B | -1.2772 | |
| 244 | E | B | -2.6593 | |
| 245 | G | B | -1.8439 | |
| 246 | E | B | -1.6469 | |
| 247 | L | B | 0.0000 | |
| 248 | L | B | 0.0000 | |
| 249 | K | B | -1.9011 | |
| 250 | P | B | -1.6181 | |
| 251 | E | B | -2.5063 | |
| 252 | N | B | 0.0000 | |
| 253 | I | B | 0.0000 | |
| 254 | A | B | -1.3441 | |
| 255 | K | B | -1.6826 | |
| 256 | I | B | 0.0000 | |
| 257 | S | B | -1.2351 | |
| 258 | H | B | -1.5906 | |
| 259 | I | B | 0.0000 | |
| 260 | P | B | -0.9284 | |
| 261 | A | B | 0.0000 | |
| 262 | V | B | 0.0000 | |
| 263 | I | B | 0.0000 | |
| 264 | V | B | 0.0000 | |
| 265 | Q | B | 0.0000 | |
| 266 | G | B | 0.0000 | |
| 267 | G | B | -0.3996 | mutated: AG267B |
| 268 | Y | B | 0.0000 | |
| 269 | D | B | 0.0000 | |
| 270 | M | B | 0.0000 | |
| 271 | V | B | 0.0000 | |
| 272 | C | B | 0.0000 | |
| 273 | P | B | 0.0000 | |
| 274 | I | B | 0.0000 | |
| 275 | T | B | 0.0000 | |
| 276 | T | B | 0.0000 | |
| 277 | A | B | 0.0000 | |
| 278 | Y | B | 0.2346 | |
| 279 | E | B | -0.6141 | |
| 280 | L | B | 0.0000 | |
| 281 | T | B | -0.5359 | |
| 282 | G | B | -0.5562 | mutated: AG282B |
| 283 | L | B | -0.1355 | |
| 284 | W | B | 0.0000 | |
| 285 | P | B | -1.2502 | |
| 286 | E | B | -2.3694 | |
| 287 | A | B | 0.0000 | |
| 288 | K | B | -1.3858 | |
| 289 | F | B | 0.1084 | |
| 290 | V | B | 0.6604 | |
| 291 | V | B | 0.7846 | |
| 292 | I | B | 0.0000 | |
| 293 | P | B | -0.9377 | |
| 294 | D | B | -2.2195 | |
| 295 | A | B | 0.0000 | |
| 296 | G | B | 0.0000 | |
| 297 | H | B | 0.0000 | |
| 298 | S | B | 0.0000 | |
| 299 | A | B | 0.0575 | |
| 300 | I | B | 0.4366 | |
| 301 | E | B | 0.0000 | |
| 302 | A | B | -0.2413 | |
| 303 | G | B | -0.6353 | |
| 304 | T | B | 0.0000 | |
| 305 | E | B | 0.0000 | |
| 306 | K | B | -1.4539 | |
| 307 | A | B | -1.1861 | |
| 308 | L | B | 0.0000 | |
| 309 | V | B | 0.0000 | |
| 310 | E | B | -2.7263 | |
| 311 | A | B | 0.0000 | |
| 312 | T | B | 0.0000 | |
| 313 | E | B | -2.3632 | |
| 314 | E | B | -2.5126 | |
| 315 | F | B | 0.0000 | |
| 316 | A | B | -1.6497 | |
| 317 | K | B | -2.0685 | |
| 318 | L | B | -0.8503 | |
| 319 | A | B | -0.2829 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine